E-GEOD-43269 - Genome wide-DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients (methylation)

Status
Released on 1 April 2013, last updated on 2 June 2014
Organism
Homo sapiens
Samples (41)
Array (1)
Protocols (46)
Description
The aim of this study is to identify, for the first time, the genome-wide DNA methylation profiles of human articular chondrocytes from OA and healtly cartilage samples. Genome wide DNA methylation profiling of normal and osteoarthritic samples. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in cartilage knee samples. Samples included 18 healthy controls and 23 OA patients. Bisulphite converted DNA from the 31 samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip v1.2
Experiment type
methylation profiling by array 
Contacts
Juan Fernandez Tajes <jfernandezt@udc.es>, Francisco J Blanco, Ignacio Rego-Perez, Juan Fernández-Tajes
Citation
Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients. Fern�ndez-Tajes J, Soto-Hermida A, V�zquez-Mosquera ME, Cort�s-Pereira E, Mosquera A, Fern�ndez-Moreno M, Oreiro N, Fern�ndez-L�pez C, Fern�ndez JL, Rego-P�rez I, Blanco FJ. , Europe PMC 23505229
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-43269.idf.txt
Sample and data relationshipE-GEOD-43269.sdrf.txt
Processed data (1)E-GEOD-43269.processed.1.zip
Array designA-GEOD-8490.adf.txt
Links