E-GEOD-42987 - Hippocampal expression data from WT, KO, R270X, and G273X mice at 4 and 9 weeks

Status
Released on 22 March 2013, last updated on 31 March 2013
Organism
Mus musculus
Samples (32)
Array (1)
Protocols (7)
Description
Mecp2 loss-of-function has been associated with altered gene expression in many tissues. We characterized gene expression changes within the hippocampi of 3 different Mecp2 loss-of-function mouse models. These studies were used to identify transcriptional differences between these mutants when the mice are largely asymptomatic (4 weeks of age) or have developed overt phenotypes (9 weeks). Hippocampal expression data from WT (Mecp2+/y), KO (Mecp2-/y), R270X (Mecp2-/y,R270XTg), and G273X (Mecp2-/y,G273XTg) mice at 4 and 9 weeks At total of 32 microarrays were performed: 4 animals of each genotype at both 4 weeks and 9 weeks of age.
Experiment type
transcription profiling by array 
Contacts
Peng Yu <geo@ncbi.nlm.nih.gov>, Huda Zoghbi, Steven Baker
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-42987.idf.txt
Sample and data relationshipE-GEOD-42987.sdrf.txt
Raw data (1)E-GEOD-42987.raw.1.zip
Processed data (1)E-GEOD-42987.processed.1.zip
Array designA-AFFY-130.adf.txt
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