E-GEOD-41459 - Transcription profiling by array of ACH-3P cells with RNAi knock-down of PRR15
Released on 11 October 2012, last updated on 30 April 2015
Proline rich 15 (PRR15) is a small nuclear protein required for normal conceptus development in the sheep. We used microarrays to assess the changes in the trophoblast transcriptome when PRR15 expression was diminished. The human first-trimester trophoblast cell line, ACH-3P, was infected with control lentivirus expressing no shRNA or lentivirus expressing shRNA to target PRR15 mRNA for degradation, with three biological replicates per treatment.
transcription profiling by array, genetic modification design
Katherine Gates <email@example.com>, Jeremy D Cantlon, Katherine C Gates, Lindsey N Goetzmann, Russell V Anthony