E-GEOD-41387 - Regulation of gene expression by YAP1

Status
Released on 1 October 2013, last updated on 2 June 2014
Organism
Homo sapiens
Samples (9)
Array (1)
Protocols (5)
Description
In order to define YAP1-specific gene expression patterns in gastric cancer, the constitutively active mutant YAP1 (YAP1-S127A) was over-expressed in MKN45 gastric cancer cells. Defined gene expression signature was later used to stratify gastric cancer patients according to the presence of the YAP1-activated signature. Three groups of samples are included: 1. Mock control; 2. Vector control; 3. YAP-S127A expression. Gene expression profiles of YAP-S127A mutant-expressing cells were compared to that of mock and vector control. Experiments were done in MKN45 gastric cancer cells.
Experiment type
transcription profiling by array 
Contacts
Sangbae Kim <skim9@mdanderson.org>, Ju S Lee, Sung S Lee, Woojin Jeong
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-41387.idf.txt
Sample and data relationshipE-GEOD-41387.sdrf.txt
Processed data (1)E-GEOD-41387.processed.1.zip
Array designA-GEOD-10558.adf.txt
Links