E-GEOD-41266 - Comparative analysis between wild type and hap5-null mutant in response to rapamycin treatment

Status
Released on 24 March 2013, last updated on 2 June 2014
Organism
Candida albicans
Samples (8)
Array (1)
Protocols (8)
Description
To identify the potential Hap5-regulated genes, we treated wild type cells and hap5 mutant cells with rapamycin and their corespondent transcriptional profiles were compared. Total 608 significant genes were identified. Among them, 343 genes are upregulated in hap5 mutant in repsonse to rapamycin while 265 genes are downregulated in comparison with the wild type. Rapamycin induced gene expression in wild type and hap5-null mutant was measured after 4.5 h growth in YPD followed by 0.5 h of incubation in the presence of 0.2 ug/ml rapamycin. Four independent experiments were performed for each strain.
Experiment type
transcription profiling by array 
Contacts
Chung-Yu Lan, Po-Chen Hsu
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-41266.idf.txt
Sample and data relationshipE-GEOD-41266.sdrf.txt
Raw data (1)E-GEOD-41266.raw.1.zip
Processed data (1)E-GEOD-41266.processed.1.zip
Array designA-GEOD-14575.adf.txt
Links