E-GEOD-41152 - HPV-related methylation in Oropharyngeal squamous cell carcinomas (OPSCC)

Status
Released on 16 September 2013, last updated on 2 June 2014
Organism
Homo sapiens
Samples (30)
Array (1)
Protocols (6)
Description
Using MCIp, we enriched highly methylated DNA from a normal mucosa control and from three OPSCC patient subgroups regarding the HPV status: group A, DNA-RNA- (Tu1-Tu5); group B, DNA+RNA- (Tu6-Tu10); group C, DNA+RNA+ (Tu11-Tu15). 3 groups of tumor biopsies, 5 samples each regarding HPV status: DNA-RNA-, DNA+RNA-, DNA+RNA+ and a control sample (normal mucosa from healthy individual): 15 tumor samples/ 1 control sample
Experiment type
methylation profiling by array 
Contacts
Dr Efterpi Kostareli <e.kostareli@dkfz.de>, Dieter Weichenhan, Efterpi Kostareli, Jochen Hess
Citation
HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas. Kostareli E, Holzinger D, Bogatyrova O, Hielscher T, Wichmann G, Keck M, Lahrmann B, Grabe N, Flechtenmacher C, Schmidt CR, Seiwert T, Dyckhoff G, Dietz A, H�fler D, Pawlita M, Benner A, Bosch FX, Plinkert P, Plass C, Weichenhan D, Hess J. , Europe PMC 23635773
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