E-GEOD-39937 - Brd2 regulates gene expression and alternative splicing

Status
Released on 3 December 2013, last updated on 9 December 2013
Organism
Homo sapiens
Samples (6)
Array (1)
Protocols (7)
Description
We analyzed a role of Brd2 protein in transcription and alternative splicing. 289 genes change alternative splicing after Brd2 knockdown and 1459 genes alter gene expression compared to cells treated with negative control siRNA. 6 samples (3 independent samples of cells treated with Brd2 siRNA, 3 samples of cells treated with negative control siRNA)
Experiment type
transcription profiling by array 
Contacts
David Stanek <stanek@img.cas.cz>, D Stanek, J Hnilicova, J Jarrells
Citation
The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing. Hnilicov� J, Hozeifi S, Stejskalov� E, Duskov� E, Poser I, Humpol�ckov� J, Hof M, Stanek D. , Europe PMC 24048450
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-39937.idf.txt
Sample and data relationshipE-GEOD-39937.sdrf.txt
Raw data (2)E-GEOD-39937.raw.1.zip, E-GEOD-39937.raw.2.zip
Processed data (1)E-GEOD-39937.processed.1.zip
Array designA-AFFY-143.adf.txt
Links