E-GEOD-39591 - Tumoral transcriptome profiling of tPTEN-/- mice.

Status
Released on 3 February 2014, last updated on 18 February 2014
Organism
Mus musculus
Samples (7)
Array (1)
Protocols (5)
Description
tPTEN-/- mice display a deletion of the PTEN tumor suppressor gene specifically in T cells (cross PTEN flox/flox x lck-Cre). They develop T cell lymphoma with a primary thymic tumor and invasion of most organ at late stage of the disease. Gene profiling was performed on whole tumors (ST3 stage 3 invasive lymphoma) and normal thymocytes (wt) using Affymetrix-MoGene-1_0-st-v1 chips.
Experiment type
transcription profiling by array 
Contacts
Kevin Lebrigand <mari@ipmc.cnrs.fr>, B Mari, C Moreilhon, J F Peyron, K Lebrigand, P Barbry, V Imbert-rezzonico
Citation
Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas. Lounnas N, Rosilio C, Nebout M, Mary D, Griessinger E, Neffati Z, Chiche J, Spits H, Hagenbeek TJ, Asnafi V, Poulsen SA, Supuran CT, Peyron JF, Imbert V. , Europe PMC 23348702
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-39591.idf.txt
Sample and data relationshipE-GEOD-39591.sdrf.txt
Raw data (1)E-GEOD-39591.raw.1.zip
Processed data (1)E-GEOD-39591.processed.1.zip
Array designA-AFFY-130.adf.txt
Links