E-GEOD-37609 - Transcription profiling by array of olfactory epithelium from Atf5+/+ and Atf5-/- mice
Released on 30 October 2012, last updated on 9 July 2014
We have found that the expression pattern of Atf5 is highly restricted to the olfactory system, strongly suggesting that Atf5 is an olfactory sensory neuron-specific transcription factor. To test this possiblity, we compared gene expression profiles in olfactory epithelium (septa and turbinates) from Atf5+/+ and Atf5-/- mice. Olfactory septa and turbinates were dissected from Atf5+/+ and Atf5-/- P0 pups from different litters (n=3 for each genotype) and pooled into a single sample. Three independent samples were prepared for each genotype.
transcription profiling by array
Sara Deibler <email@example.com>, Michael R Green, Shu-Zong Wang
Transcription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neurons. Wang SZ, Ou J, Zhu LJ, Green MR. , Europe PMC 23090999