E-GEOD-36572 - Synergistic effects of TRAIL and taurolidine on soft tissue sarcoma cell lines

Status
Released on 17 March 2013, last updated on 2 June 2014
Organism
Homo sapiens
Samples (12)
Array (1)
Protocols (8)
Description
Microarray analysis revealed differential gene expression patterns of rhabdomyosarcoma (A-204), leiomyosarcoma (SK-LMS-1) and epithelioid cell sarcoma (VA-ES-BJ) cells treated with TRAIL and/or taurolidine. To explore new therapeutic options in the treatment of sarcomas, we tested the antibiotic taurolidine (TRD) on A-204, SK-LMS-1 and VA-ES-BJ carcinoma cell lines alone and in combination with rhTRAIL (TNF related apoptosis-inducing ligand). Gene expression was analysed by RNA microarray. Cell lines were treated with Taurolidine, Trail and a combination of both and compaired to untreated cells
Experiment type
transcription profiling by array 
Contacts
Ludger Klein-Hitpass <ludger.klein-hitpass@uni-essen.de>, A Daigeler, K Harati, L Klein-Hitpass
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-36572.idf.txt
Sample and data relationshipE-GEOD-36572.sdrf.txt
Raw data (1)E-GEOD-36572.raw.1.zip
Processed data (1)E-GEOD-36572.processed.1.zip
Array designA-AFFY-44.adf.txt
Links