E-GEOD-36336 - Transcription profiling by array of kidneys from diabetic wild type and T3-/- mice

Status
Released on 25 April 2014, last updated on 24 June 2014
Organism
Mus musculus
Samples (6)
Array (1)
Protocols (6)
Description
Activation of A Disintegrin and A Metalloprotease Domain17 (ADAM17) is involved in nephropathy, but the role of this metalloprotease and its inhibitor TIMP3 in diabetic kidney disease is unclear. We used microarray profiling to find genes differentially expressed in the 2 genotypes which could explain the more severe diabetic kidney disease features observed in T3-/- mice compared to the WT littermates. Total RNA was extracted from 3 WT and 3 Timp3-/- diabetic kidneys
Experiment type
transcription profiling by array 
Contacts
Ivan Arisi <i.arisi@ebri.it>, Loredana Fiorentino, Massimo Federici
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-36336.idf.txt
Sample and data relationshipE-GEOD-36336.sdrf.txt
Raw data (1)E-GEOD-36336.raw.1.zip
Processed data (1)E-GEOD-36336.processed.1.zip
Array designA-AFFY-45.adf.txt
Links