E-GEOD-31947 - Profiling aorta from high fat diet (HFD)-fed ApoE KO and wild type C57BL6 mice

Status
Released on 22 March 2013, last updated on 2 June 2014
Organism
Mus musculus
Samples (12)
Array (1)
Protocols (7)
Description
This program aimed to understand gene expression changes in aorta during atherosclerotic lesion progression with an objective to identify genes that may present new opportunities for drug intervention The HFD-fed ApoE KO mice aorta profiling data was analyzed by identifying genes that were up- and down-regulated at selected p value and fold change in comparison to the HFD-fed WT C57BL6 controls.
Experiment type
transcription profiling by array 
Contacts
Citation
Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers. Wang IM, Zhang B, Yang X, Zhu J, Stepaniants S, Zhang C, Meng Q, Peters M, He Y, Ni C, Slipetz D, Crackower MA, Houshyar H, Tan CM, Asante-Appiah E, O'Neill G, Luo MJ, Thieringer R, Yuan J, Chiu CS, Lum PY, Lamb J, Boie Y, Wilkinson HA, Schadt EE, Dai H, Roberts C. , Europe PMC 22806142
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-31947.idf.txt
Sample and data relationshipE-GEOD-31947.sdrf.txt
Processed data (1)E-GEOD-31947.processed.1.zip
Array designA-GEOD-3677.adf.txt
Links