E-GEOD-29414 - To examine the influence of the early stress of maternal separation on the hippocampal transcriptome in middle-aged life

Status
Released on 11 October 2013, last updated on 2 June 2014
Organism
Rattus norvegicus
Samples (8)
Array (1)
Protocols (6)
Description
In this study, we examined the consequences of the early stress (ES) of maternal separation on hippocampal gene expression in middle-aged animals. Middle-aged (15 months old) ES animals exhibit hippocampal transcriptome changes with a significant regulation of genes associated with ion binding, transcriptional regulation, cellular projection, cellular stress responsive pathways, neuronal development and chromatin remodeling. Agilent one-color experiment, Agilent-024724 Genotypic-designed Custom Rattus Norvegicus 8x15k; Organism: Rattus norvegicus; Labeling kit: Agilent Quick-Amp labeling Kit (p/n5190-0442); Biological replicates: 5 per early stress group, 3 per control group
Experiment type
transcription profiling by array 
Contacts
Citation
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-29414.idf.txt
Sample and data relationshipE-GEOD-29414.sdrf.txt
Raw data (1)E-GEOD-29414.raw.1.zip
Processed data (1)E-GEOD-29414.processed.1.zip
Array designA-GEOD-13186.adf.txt
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