E-GEOD-28737 - Conditional deletion of Bcl6 in naive B cells

Status
Released on 21 September 2012, last updated on 1 October 2012
Organism
Mus musculus
Samples (12)
Array (1)
Protocols (6)
Description
Bcl6 germline deletion causes a prominent inflammatory disease, owing to over-expression of Th2 cytokines, and affects the properties of B cells prior to immunization. Therefore we established the B cell-specific Bcl6 deletion mice and analyze the gene expression of naive B cells under physiological conditions. Total RNAs of splenic follicular and marginal zone B cells from Bcl6(flox/flox), Bcl6(+/flox) or Bcl6(+/+) mice heterozygous for mb1-cre were extracted and analysed on Affymetrix microarrays.
Experiment type
transcription profiling by array 
Contacts
Kaji Tomohiro <t-kaji@rcai.riken.jp>, Akiko Sugimoto, Atsushi Hijikata, Masaki Hikida, Toshitada Takemori
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-28737.idf.txt
Sample and data relationshipE-GEOD-28737.sdrf.txt
Raw data (1)E-GEOD-28737.raw.1.zip
Processed data (1)E-GEOD-28737.processed.1.zip
Array designA-AFFY-45.adf.txt
R ExpressionSetE-GEOD-28737.eSet.r
Links