E-GEOD-27713 - Genome-wide analysis of gene expression patterns in mir-122 knockout mice livers
Released on 6 August 2012, last updated on 13 August 2012
To invesigate the physiology roles of mir-122 in liver, we performed expression profiling of mir-122 knockout mice and the control B6/129 mice. Total RNA was extracted from four mir-122 knockout mice and three control mice of 2 months of age. Gene expression was quantified by robust multi-array analysis (RMA) using the Genomic Suite software from Partek.
transcription profiling by array
Ann-Ping Tsou, Chu-Sui Hsu, Hua-Chien Chen, Shu-Jen Chen, Wei-Chih Tsai, Yi Huang
MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. Tsai WC, Hsu SD, Hsu CS, Lai TC, Chen SJ, Shen R, Huang Y, Chen HC, Lee CH, Tsai TF, Hsu MT, Wu JC, Huang HD, Shiao MS, Hsiao M, Tsou AP. , Europe PMC 22820290