E-GEOD-2298 - Transcription profiling of human HLE B-3 cells transfected with hGSTA4-4 expressing vector vs. controls
Submitted on 18 February 2005, released on 12 June 2008, last updated on 27 March 2012
HLE B-3 cells were transfected with either empty vector or hGSTA4-4 expressing vector to lower intracellular 4-hydroxynonenal levels. hGSTA4-transfected sample has lower HNE levels than pTarget-transfected sample.
transcription profiling by array, unknown experiment type
Depletion of 4-hydroxynonenal in hGSTA4-transfected HLE B-3 cells results in profound changes in gene expression. Brad Patrick, Jie Li, Prince V S Jeyabal, Prasada M R V Reddy, Yusong Yang, Rajendra Sharma, Mala Sinha, Bruce Luxon, Piotr Zimniak, Sanjay Awasthi, Yogesh C Awasthi. Biochem Biophys Res Commun 334(2):425-32 (2005)