E-GEOD-21681 - Gene expression profile in three regions of the hippocampus of middle aged and old rats exposed to dietary restriction

Status
Released on 8 June 2010, last updated on 10 September 2015
Organism
Rattus norvegicus
Samples (45)
Array (1)
Protocols (8)
Description
Aging is associated with a decline in hippocampal mediated learning and memory, a process which can be ameliorated by dietary (caloric) restriction. We used Affymetrix gene expression analysis to monitor changes in three regions of the hippocampus (CA1, CA3, DG) of middle aged (18 months) and old (28 month) rats that were exposed to dietary restriction. Old rats were determined to be good performers (GP) or poor performers (PP) in behavioural tests to assess their hippocampal function. We used Affymetrix gene expression analysis to monitor changes in three regions of the hippocampus (CA1, CA3, DG) of middle aged (18 months) and old (28 month) rats that were exposed to dietary restriction.
Experiment type
transcription profiling by array 
Contacts
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-21681.idf.txt
Sample and data relationshipE-GEOD-21681.sdrf.txt
Raw data (1)E-GEOD-21681.raw.1.zip
Processed data (1)E-GEOD-21681.processed.1.zip
Array designA-AFFY-43.adf.txt
Links