E-GEOD-19347 - microRNA expression data from pediatric primary intracranial germ cell tumor

Status
Submitted on 7 December 2009, released on 14 May 2010, last updated on 1 May 2014
Organism
Homo sapiens
Samples (12)
Array (1)
Protocols (6)
Description
Intracranial pediatric germ cell tumors (GCTs) have different histological differentiations, prognosis and clinical behaviors. Prognosis of patients with germinoma and mature teratoma is good, while patients with other types of GCTs, termed as nongerminomatous malignant germ cell tumors (NGMGCTs), require more extensive drug and irradiation treatment regimen. The mechanisms underlying different prognosis of various GCT subgroups remain elusive. We presented the first miRNA profile of pediatric primary intracranial GCTs. 12 central nervous system GCT cases with different histological subtypes are subjected to miRNA expression analysis. The histological subtypes are germinoma, mixed GCT of germinoma and mature teratoma , immature teratoma , mixed GCTs of NGMGCTs category, yolk sac tumor, immature teratoma, and embryonal carcinoma.
Experiment type
transcription profiling by array 
Contacts
Yu Hsuan Wu <allenwu03@gmail.com>, Hsei-Wei Wang, Yu-Hsuan Wu
Citation
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-19347.idf.txt
Sample and data relationshipE-GEOD-19347.sdrf.txt
Raw data (1)E-GEOD-19347.raw.1.zip
Processed data (1)E-GEOD-19347.processed.1.zip
Array designA-GEOD-8227.adf.txt
Links