E-GEOD-1839 - Transcription profiling of uteruses from Alpk:APfCD-1 mice treated with arachis oil (AO) vehicle, 17beta-estradiol (E2), diethylstilbestrol (DES), or genistein (GEN) to study the effects of E2, GEN, and DES on gene transcription.
Released on 13 December 2007, last updated on 2 June 2014
Three independent replicates of 4 groups of immature (19/20 days of age) Alpk:APfCD-1 mice were treated with arachis oil (AO) vehicle, 2.5ug/kg 17beta-estradiol (E2), 2ug/kg diethylstilbestrol (DES), or 50mg/kg genistein (GEN), via 3 daily subcutaneous injection, and sacrificed 72hr after initial dose.
transcription profiling by array, co-expression, compound treatment
The need to decide if all estrogens are intrinsically similar. Jonathan G Moggs, John Ashby, Helen Tinwell, Fei Ling Lim, David J Moore, Ian Kimber, George Orphanides.