E-GEOD-1819 - Transcription profiling by array of uteruses from immature Alpk:APfCD-1 mice treated with arachis oil vehicle (AO), 17beta-estradiol (E2), or genistein (GEN) to study the effects of E2 and GEN on gene expression.
Released on 13 December 2007, last updated on 5 December 2012
Immature (19/20 days of age) Alpk:APfCD-1 mice were treated with arachis oil (AO) vehicle, 0.4mg/kg 17beta-estradiol (E2), or 250mg/kg genistein (GEN), via a single subcutaneous injection, and sacrificed at 1hr, 2hr, 4hr, 8hr, 24hr, 48hr, 72hr post dose.
transcription profiling by array, co-expression, compound treatment, time series
The need to decide if all estrogens are intrinsically similar. Jonathan G Moggs, John Ashby, Helen Tinwell, Fei Ling Lim, David J Moore, Ian Kimber, George Orphanides. Environ Health Perspect 112(11):1137-42 (2004)