E-GEOD-17375 - Gene expression in colon cancer stem cells (CSC) cultures identified by Wnt signaling levels
Released on 1 December 2009, last updated on 2 June 2014
Primary colon CSC cultures were transduced with a Wnt responsive construct (TOP-GFP) and were single cell cloned. 10% highest and lowest TOP-GFP cell fractions were FACS sorted and arrayed. Primary colon CSC cultures with a responsive construct (TOP-GFP): high and low TOP-GFP cell fractions. 4 samples.
transcription profiling by array
Louis Vermeulen <email@example.com>, Felipe de Sousa E Melo, Jan_Paul Medema, Louis Vermeulen
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP. , Europe PMC 20418870