E-GEOD-1300 - Transcription profiling of human hereditary spastic paraplegia patients

Status
Released on 29 July 2007, last updated on 12 October 2011
Organism
Homo sapiens
Samples (7)
Arrays (2)
Protocols (2)
Description
The goal of this project is to study differentially expressed genes in patients affected by Hereditary Spastic Paraplegia (HSP) linked to mutations of the gene encoding spastin an ubiquitously expressed protein that has recently been shown to be involved in microtubule regulation and vesicle trafficking by cell culture studies. Gene profiling was done with Affymetrix U95Av2 GeneChips using the total RNA extracted from muscle biopsies of 3 SPG4-linked HSP patients.
Experiment types
transcription profiling by array, co-expression, individual comparison
Contact
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-1300.idf.txt
Sample and data relationshipE-GEOD-1300.sdrf.txt
Raw data (1)E-GEOD-1300.raw.1.zip
Processed data (1)E-GEOD-1300.processed.1.zip
Array designsA-AFFY-1.adf.txt, A-AFFY-33.adf.txt
R ExpressionSetE-GEOD-1300.eSet.r
Links