E-GEOD-1145 - changes in cardiac transcription profiles brought about by heart failure

Status
Released on 24 March 2004, last updated on 20 April 2016
Organism
Homo sapiens
Samples (107)
Arrays (2)
Protocols (2)
Description
To establish changes in cardiac transcription profiles brought about by heart failure we collected myocardial samples from patients undergoing cardiac transplantation whose failure arises from different etiologies (e.g. idiopathic dilated cardiomyopathy, ischemic cardiomyopathy, alcoholic cardiomyopathy, valvular cardiomyopathy, and hypertrophic cardiomyopathy) and from "normal" organ donors whose hearts cannot be used for transplants. The transcriptional profile of the mRNA in these samples will be measured with gene array technology. Changes in transcriptional profiles can be correlated with the physiologic profile of heart-failure hearts acquired at the time of transplantation. Keywords: other
Experiment type
transcription profiling by array 
Contacts
Martina Schinke <geo@ncbi.nlm.nih.gov>, Allen Paul, Jeffrey Brown, Jozef Bartunek, Lauren E Riggi, Masako Tsubakihara, Paul Allen, Seigo Izumo
MIAME
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