E-GEOD-11348 - Transcription profiling by array of human nasal epithelium from patients infected with HRV-16 rhinovirus

Status
Released on 12 June 2008, last updated on 2 May 2014
Organism
Homo sapiens
Samples (93)
Array (1)
Protocols (6)
Description
This study provides a comprehensive evaluation of changes in gene expression during rhinovirus infections in vivo. Subjects were experimentally infected with HRV-16 rhinovirus (RV16) or sham infected (CONTROL). Nasal epithelial scrapings collected and processed for microarray analysis. Only subjects exhibiting rhinovirus infection were analyzed. Experiment Overall Design: Randomized, parallel group study. A total of 31 subjects was analyzed: 15 infected and 16 controls. Nasal scapings were taken 14 days prior to infection (d14) and 8 hours (d0) and 2 days (d2) after infection. For each collection, alternating nostrils were used (e.g. -14d = left, 8hr = right, 2d=left) and subjects were randomized for collection (e.g. LRL, RLR).
Experiment types
transcription profiling by array, unknown experiment type
Contact
Citation
Gene expression profiles during in vivo human rhinovirus infection: insights into the host response. Proud D, Turner RB, Winther B, Wiehler S, Tiesman JP, Reichling TD, Juhlin KD, Fulmer AW, Ho BY, Walanski AA, Poore CL, Mizoguchi H, Jump L, Moore ML, Zukowski CK, Clymer JW. , Europe PMC 18658112
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-11348.idf.txt
Sample and data relationshipE-GEOD-11348.sdrf.txt
Raw data (3)E-GEOD-11348.raw.1.zip, E-GEOD-11348.raw.2.zip, E-GEOD-11348.raw.3.zip
Processed data (1)E-GEOD-11348.processed.1.zip
Array designA-AFFY-44.adf.txt
R ExpressionSetE-GEOD-11348.eSet.r
Links