E-GEOD-11331 - Ribosomal protein S6 Rps6 heterozygous null deletion effect on footpad epidermis
Submitted on 1 May 2008, released on 12 June 2008, last updated on 27 March 2012
Mutant and non-mutant footpad. McGowan et al. in press Keywords: Mutant vs. non-mutant The tissue (footpad epidermis) is from a conditional heterozygous null deletion of Rps6. One copy of Rps6 was deleted from keratinocytes in the skin using the K5.Cre transgene. K5Cre x Rps6^loxP
unknown experiment type
Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects. McGowan KA, Li JZ, Park CY, Beaudry V, Tabor HK, Sabnis AJ, Zhang W, Fuchs H, de Angelis MH, Myers RM, Attardi LD, Barsh GS.