E-GEOD-1109 - CEA_SGF:E00002#REtsAF-Bcl2_ZVAD

Status
Submitted on 5 March 2004, released on 1 June 2004, last updated on 27 March 2012
Organism
Mus musculus
Samples (24)
Array (1)
Protocols (1)
Description
p53 can induce apoptosis through multiple mechanisms including transactivation, transrepression or protein interactions but the determinism of the choice between them is poorly understood. In order to know the role of caspases in this choice, effect of caspase inhibition by ZVAD on p53 target genes transcription is tested by DNA chip analysis.
Experiment type
unknown experiment type 
Contact
Citation
Transcriptional repression by p53 promotes a Bcl-2-insensitive and mitochondria-independent pathway of apoptosis. Godefroy N, Bouleau S, Gruel G, Renaud F, Rincheval V, Mignotte B, Tronik-Le Roux D, Vayssière JL.
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-GEOD-1109.idf.txt
Sample and data relationshipE-GEOD-1109.sdrf.txt
Processed data (1)E-GEOD-1109.processed.1.zip
Experiment designE-GEOD-1109.biosamples.png, E-GEOD-1109.biosamples.svg
Array designA-GEOD-1063.adf.txt
Links