E-GEOD-10316 - Transcription profiling of human monocyte-derived dendritic cells stimulated with LPS, Poly(I:C), CD40L or a combination of IL-1-b, IL-6, TNF-a and PGE2

Status
Submitted on 29 January 2008, released on 9 February 2009, last updated on 10 June 2011
Organism
Homo sapiens
Samples (13)
Array (1)
Protocols (5)
Description
The ubiquitin proteasome system (UPS) is known to possess important regulatory functions in the immune response. To gain a better and first comprehensive insight into the mechanisms underlying the conversion of immature to mature DC in terms of the expression of UPS related genes, we undertook a comparative gene expression profiling during DC maturation in response to four different prototypic maturation stimuli. Experiment Overall Design: Monocyte-derived DC were harvested at 3 different periods of time following stimulation for RNA extraction and hybridization on Affymetrix microarrays.
Experiment types
transcription profiling by array, unknown experiment type
Contact
Elke Krueger
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-10316.idf.txt
Sample and data relationshipE-GEOD-10316.sdrf.txt
Raw data (1)E-GEOD-10316.raw.1.zip
Processed data (1)E-GEOD-10316.processed.1.zip
Array designA-AFFY-44.adf.txt
R ExpressionSetE-GEOD-10316.eSet.r
Links