E-CBIL-7 - Transcription profiling of mouse islets treated with PANcreatic DERived factor for 48 or 72 h to elucidate the genetic mechanisms of PANDER-induced cell death

Status
Released on 24 May 2006, last updated on 2 June 2014
Organism
Mus musculus
Samples (14)
Array (1)
Protocols (9)
Description
Expression profiling using the UPenn Mouse PancChip 5.0 was used to elucidate the genetic mechanisms of PANDER-induced cell death in pancreatic islets. Murine islets were treated with PANDER (PANcreatic DERived factor) for 48 or 72 h (n=4 and n=3 respectively). Following linear amplification, the RNA was matched for purity using Quantitative PCR.
Experiment types
transcription profiling by array, compound treatment, time series
Contact
Citation
PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21). Brant R. Burkhardt, Scott R. Greene, Peter White, Ryan K. Wong, John E. Brestelli, Jichun Yang, Claudia E. Robert, Todd M. Brusko, Clive H. Wasserfall, Jianmei Wu, Mark A. Atkinson, Zhiyong Gao, Klaus H. Kaestner and Bryan A. Wolf.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-CBIL-7.idf.txt
Sample and data relationshipE-CBIL-7.sdrf.txt
Raw data (1)E-CBIL-7.raw.1.zip
Experiment designE-CBIL-7.biosamples.png, E-CBIL-7.biosamples.svg
Array designA-CBIL-2.adf.txt
Links