E-CBIL-25 - Transcription profiling of mouse skeletal muscle in streptozotocin diabetes with or without insulin treatment

Status
Released on 5 April 2007, last updated on 21 February 2012
Organism
Mus musculus
Samples (27)
Array (1)
Protocols (8)
Description
Metabolic abnormalities underlying diabetes are primarily the result of the lack of adequate insulin action and the associated changes in protein phosphorylation and gene expression. Affymetrix oligonucleotide microarrays were used to study the changes in the transcriptional program of mouse skeletal muscle in insulin-deficient diabetes. Mice which were made diabetic by streptozotocin treatment were compared to controls. Also, the reversibility of these changes was ascertained by treating a subset of the diabetic mice with insulin.
Experiment types
 compound treatment, transcription profiling by array
Contact
Citation
MIAME
PlatformsProtocolsFactorsProcessedRaw
Files
Investigation descriptionE-CBIL-25.idf.txt
Sample and data relationshipE-CBIL-25.sdrf.txt
Raw data (1)E-CBIL-25.raw.1.zip
Processed data (1)E-CBIL-25.processed.1.zip
Experiment designE-CBIL-25.biosamples.png, E-CBIL-25.biosamples.svg
Array designA-AFFY-6.adf.txt
R ExpressionSetE-CBIL-25.eSet.r
Links