Reza Salek

Reza Salek

Project Manager (COSMOS), MetaboLights Curator - Steinbeck team: Cheminformatics and metabolism

ORCID iD: 0000-0001-8604-1732

Tel:+ 44 (0) 1223 494 502 / Fax:+ 44 (0) 1223 494 468



Getting the right answers: understanding metabolomics challenges.
Beisken S, Eiden M, Salek RM.
Expert Rev Mol Diagn Volume 15 (2015) p.97-109
DOI: 10.1586/14737159.2015.974562

Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review.
Emwas AH, Luchinat C, Turano P, Tenori L, Roy R, Salek RM, Ryan D, Merzaban JS, Kaddurah-Daouk R, Zeri AC, Nagana Gowda GA, Raftery D, Wang Y, Brennan L, Wishart DS.
Metabolomics Volume 11 (2015) p.872-894
DOI: 10.1007/s11306-014-0746-7


Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.
Rueedi R, Ledda M, Nicholls AW, Salek RM, Marques-Vidal P, Morya E, Sameshima K, Montoliu I, Da Silva L, Collino S, Martin FP, Rezzi S, Steinbeck C, Waterworth DM, Waeber G, Vollenweider P, Beckmann JS, Le Coutre J, Mooser V, Bergmann S, Genick UK, Kutalik Z.
PLoS Genet Volume 10 (2014) p.e1004132
DOI: 10.1371/journal.pgen.1004132

The mzTab data exchange format: communicating mass-spectrometry-based proteomics and metabolomics experimental results to a wider audience.
Griss J, Jones AR, Sachsenberg T, Walzer M, Gatto L, Hartler J, Thallinger GG, Salek RM, Steinbeck C, Neuhauser N, Cox J, Neumann S, Fan J, Reisinger F, Xu QW, Del Toro N, Pérez-Riverol Y, Ghali F, Bandeira N, Xenarios I, Kohlbacher O, Vizcaíno JA, Hermjakob H.
Mol Cell Proteomics Volume 13 (2014) p.2765-2775
DOI: 10.1074/mcp.o113.036681

Dolphin: a tool for automatic targeted metabolite profiling using 1D and 2D (1)H-NMR data.
Gómez J, Brezmes J, Mallol R, Rodríguez MA, Vinaixa M, Salek RM, Correig X, Cañellas N.
Anal Bioanal Chem Volume 406 (2014) p.7967-7976
DOI: 10.1007/s00216-014-8225-6

Meeting new challenges: The 2014 HUPO-PSI/COSMOS Workshop: 13-15 April 2014, Frankfurt, Germany.
Orchard S, Albar JP, Binz PA, Kettner C, Jones AR, Salek RM, Vizcaino JA, Deutsch EW, Hermjakob H.
Proteomics Volume 14 (2014) p.2363-2368
DOI: 10.1002/pmic.201470164

Metabolic differences in ripening of Solanum lycopersicum 'Ailsa Craig' and three monogenic mutants.
Beisken S, Earll M, Baxter C, Portwood D, Ament Z, Kende A, Hodgman C, Seymour G, Smith R, Fraser P, Seymour M, Salek RM, Steinbeck C.
Sci Data Volume 1 (2014) p.140029
DOI: 10.1038/sdata.2014.29


The MetaboLights repository: curation challenges in metabolomics.
Salek RM, Haug K, Conesa P, Hastings J, Williams M, Mahendraker T, Maguire E, González-Beltrán AN, Rocca-Serra P, Sansone SA, Steinbeck C.
Database (Oxford) Volume 2013 (2013) p.bat029
DOI: 10.1093/database/bat029

Biomarkers of food intake and metabolite differences between plasma and red blood cell matrices; a human metabolomic profile approach.
Catalán Ú, Rodríguez MÁ, Ras MR, Maciá A, Mallol R, Vinaixa M, Fernández-Castillejo S, Valls RM, Pedret A, Griffin JL, Salek R, Correig X, Motilva MJ, Solà R.
Mol Biosyst Volume 9 (2013) p.1411-1422
DOI: 10.1039/c3mb25554a

MetaboLights--an open-access general-purpose repository for metabolomics studies and associated meta-data.
Haug K, Salek RM, Conesa P, Hastings J, de Matos P, Rijnbeek M, Mahendraker T, Williams M, Neumann S, Rocca-Serra P, Maguire E, González-Beltrán A, Sansone SA, Griffin JL, Steinbeck C.
Nucleic Acids Res Volume 41 (2013) p.d781-6
DOI: 10.1093/nar/gks1004

Dissemination of metabolomics results: role of MetaboLights and COSMOS.
Salek RM, Haug K, Steinbeck C.
Gigascience Volume 2 (2013) p.8
DOI: 10.1186/2047-217x-2-8

The role of reporting standards for metabolite annotation and identification in metabolomic studies.
Salek RM, Steinbeck C, Viant MR, Goodacre R, Dunn WB.
Gigascience Volume 2 (2013) p.13
DOI: 10.1186/2047-217x-2-13


Metabolomics of human breast cancer: new approaches for tumor typing and biomarker discovery.
Denkert C, Bucher E, Hilvo M, Salek R, Orešič M, Griffin J, Brockmöller S, Klauschen F, Loibl S, Barupal DK, Budczies J, Iljin K, Nekljudova V, Fiehn O.
Genome Med Volume 4 (2012) p.37

Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue - a GC-TOFMS based metabolomics study.
Budczies J, Denkert C, Müller BM, Brockmöller SF, Klauschen F, Györffy B, Dietel M, Richter-Ehrenstein C, Marten U, Salek RM, Griffin JL, Hilvo M, Orešič M, Wohlgemuth G, Fiehn O.
BMC Genomics Volume 13 (2012) p.334
DOI: 10.1186/1471-2164-13-334

MetaboLights: towards a new COSMOS of metabolomics data management.
Steinbeck C, Conesa P, Haug K, Mahendraker T, Williams M, Maguire E, Rocca-Serra P, Sansone SA, Salek RM, Griffin JL.
Metabolomics Volume 8 (2012) p.757-760
DOI: 10.1007/s11306-012-0462-0


The study of mammalian metabolism through NMR-based metabolomics.
Salek R, Cheng KK, Griffin J.
Methods Enzymol Volume 500 (2011) p.337-351
DOI: 10.1016/b978-0-12-385118-5.00017-7

A metabolomic comparison of mouse models of the Neuronal Ceroid Lipofuscinoses.
Salek RM, Pears MR, Cooper JD, Mitchison HM, Pearce DA, Mortishire-Smith RJ, Griffin JL.
J Biomol NMR Volume 49 (2011) p.175-184
DOI: 10.1007/s10858-011-9491-7

A Metadata description of the data in "A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.".
Griffin JL, Atherton HJ, Steinbeck C, Salek RM.
BMC Res Notes Volume 4 (2011) p.272
DOI: 10.1186/1756-0500-4-272


¹H nuclear magnetic resonance spectroscopy characterisation of metabolic phenotypes in the medulloblastoma of the SMO transgenic mice.
Hekmatyar SK, Wilson M, Jerome N, Salek RM, Griffin JL, Peet A, Kauppinen RA.
Br J Cancer Volume 103 (2010) p.1297-1304
DOI: 10.1038/sj.bjc.6605890

A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease.
Salek RM, Xia J, Innes A, Sweatman BC, Adalbert R, Randle S, McGowan E, Emson PC, Griffin JL.
Neurochem Int Volume 56 (2010) p.937-947
DOI: 10.1016/j.neuint.2010.04.001


A metabolomic study of brain tissues from aged mice with low expression of the vesicular monoamine transporter 2 (VMAT2) gene.
Salek RM, Colebrooke RE, Macintosh R, Lynch PJ, Sweatman BC, Emson PC, Griffin JL.
Neurochem Res Volume 33 (2008) p.292-300
DOI: 10.1007/s11064-007-9542-3


Metabolomic applications to neuroscience: more challenges than chances?
Griffin JL, Salek RM.
Expert Rev Proteomics Volume 4 (2007) p.435-437
DOI: 10.1586/14789450.4.4.435

Metabolomic investigation of CLN6 neuronal ceroid lipofuscinosis in affected South Hampshire sheep.
Pears MR, Salek RM, Palmer DN, Kay GW, Mortishire-Smith RJ, Griffin JL.
J Neurosci Res Volume 85 (2007) p.3494-3504
DOI: 10.1002/jnr.21343

A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.
Salek RM, Maguire ML, Bentley E, Rubtsov DV, Hough T, Cheeseman M, Nunez D, Sweatman BC, Haselden JN, Cox RD, Connor SC, Griffin JL.
Physiol Genomics Volume 29 (2007) p.99-108
DOI: 10.1152/physiolgenomics.00194.2006


NMR studies of the heat shock protein 90 N-terminal domain.
Salek RM.
Volume (2005) p.


Backbone resonance assignments of the 25kD N-terminal ATPase domain from the Hsp90 chaperone.
Salek RM, Williams MA, Prodromou C, Pearl LH, Ladbury JE.
J Biomol NMR Volume 23 (2002) p.327-328
DOI: 10.1023/a:1020268712347


Determination of the pesticide naptalam and its degradation products by positive and negative ion mass spectrometry.
Ghassempour A, Arshadi MR, Asghari FS.
Fresenius J Anal Chem Volume 369 (2001) p.176-183
DOI: 10.1007/s002160000589