Pedro Beltrao

Pedro Beltrao

Group Leader - Beltrao research group

PhD in Biology, University of Aveiro (research conducted at EMBL-Heidelberg), 09/2007. Postdoctoral research at the University of California San Francisco. Group leader at EMBL-EBI since 2013.

ORCID iD: 0000-0002-2724-7703

Tel:+44 (0) 1223 494 610 / Fax:+44 (0) 1223 494 468

Research

Find out about research activity in the Beltrao research group

Publications

2016

Uncovering Phosphorylation-Based Specificities through Functional Interaction Networks.
Wagih O, Sugiyama N, Ishihama Y, Beltrao P.
Molecular & cellular proteomics : MCP Volume 15 (2016) p.236-245

2015

Towards the computational design of protein post-translational regulation.
Strumillo M, Beltrao P.
Bioorganic & medicinal chemistry Volume 23 (2015) p.2877-2882

Kinase-two-hybrid: towards the conditional interactome.
Ochoa D, Beltrao P.
Molecular systems biology Volume 11 (2015) p.798

Differential genetic interactions of yeast stress response MAPK pathways.
Martin H, Shales M, Fernandez-Piñar P, Wei P, Molina M, Fiedler D, Shokat KM, Beltrao P, Lim W, Krogan NJ.
Molecular systems biology Volume 11 (2015) p.800

Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes.
Johnson JR, Santos SD, Johnson T, Pieper U, Strumillo M, Wagih O, Sali A, Krogan NJ, Beltrao P.
PLoS computational biology Volume 11 (2015) p.e1004362

2014

Phosphoproteomic analysis reveals regulatory mechanisms at the kidney filtration barrier.
Rinschen MM, Wu X, König T, Pisitkun T, Hagmann H, Pahmeyer C, Lamkemeyer T, Kohli P, Schnell N, Schermer B, Dryer S, Brooks BR, Beltrao P, Krueger M, Brinkkoetter PT, Benzing T.
Journal of the American Society of Nephrology : JASN Volume 25 (2014) p.1509-1522

2013

Evolution and functional cross-talk of protein post-translational modifications.
Beltrao P, Bork P, Krogan NJ, van Noort V.
Molecular systems biology Volume 9 (2013) p.714

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
Nature methods Volume 10 (2013) p.676-682

2012

Systematic functional prioritization of protein posttranslational modifications.
Beltrao P, Albanèse V, Kenner LR, Swaney DL, Burlingame A, Villén J, Lim WA, Fraser JS, Frydman J, Krogan NJ.
Cell Volume 150 (2012) p.413-425

Comparative interaction networks: bridging genotype to phenotype.
Beltrao P, Ryan C, Krogan NJ.
Advances in experimental medicine and biology Volume 751 (2012) p.139-156

Hierarchical modularity and the evolution of genetic interactomes across species.
Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, Edelmann W, Keogh MC, Greene D, Tang C, Cunningham P, Shokat KM, Cagney G, Svensson JP, Guthrie C, Espenshade PJ, Ideker T, Krogan NJ.
Molecular cell Volume 46 (2012) p.691-704

2011

Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress.
Charles GM, Chen C, Shih SC, Collins SR, Beltrao P, Zhang X, Sharma T, Tan S, Burlingame AL, Krogan NJ, Madhani HD, Narlikar GJ.
Proceedings of the National Academy of Sciences of the United States of America Volume 108 (2011) p.10620-10625

Phenotypic landscape of a bacterial cell.
Nichols RJ, Sen S, Choo YJ, Beltrao P, Zietek M, Chaba R, Lee S, Kazmierczak KM, Lee KJ, Wong A, Shales M, Lovett S, Winkler ME, Krogan NJ, Typas A, Gross CA.
Cell Volume 144 (2011) p.143-156

2010

Quantitative genetic interactions reveal biological modularity.
Beltrao P, Cagney G, Krogan NJ.
Cell Volume 141 (2010) p.739-745

Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action.
Kapitzky L, Beltrao P, Berens TJ, Gassner N, Zhou C, Wüster A, Wu J, Babu MM, Elledge SJ, Toczyski D, Lokey RS, Krogan NJ.
Molecular systems biology Volume 6 (2010) p.451

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.
Lefebvre C, Rajbhandari P, Alvarez MJ, Bandaru P, Lim WK, Sato M, Wang K, Sumazin P, Kustagi M, Bisikirska BC, Basso K, Beltrao P, Krogan N, Gautier J, Dalla-Favera R, Califano A.
Molecular systems biology Volume 6 (2010) p.377

2009

ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs.
Encinar JA, Fernandez-Ballester G, Sánchez IE, Hurtado-Gomez E, Stricher F, Beltrao P, Serrano L.
Bioinformatics (Oxford, England) Volume 25 (2009) p.2418-2424

Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.
Beltrao P, Trinidad JC, Fiedler D, Roguev A, Lim WA, Shokat KM, Burlingame AL, Krogan NJ.
PLoS biology Volume 7 (2009) p.e1000134

Microblogging the ISMB: a new approach to conference reporting.
Saunders N, Beltrão P, Jensen L, Jurczak D, Krause R, Kuhn M, Wu S.
PLoS computational biology Volume 5 (2009) p.e1000263

Structure-based prediction of the Saccharomyces cerevisiae SH3-ligand interactions.
Fernandez-Ballester G, Beltrao P, Gonzalez JM, Song YH, Wilmanns M, Valencia A, Serrano L.
Journal of molecular biology Volume 388 (2009) p.902-916

2008

Analyzing protein interaction networks using structural information.
Kiel C, Beltrao P, Serrano L.
Annual review of biochemistry Volume 77 (2008) p.415-441

Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm.
Sánchez IE, Beltrao P, Stricher F, Schymkowitz J, Ferkinghoff-Borg J, Rousseau F, Serrano L.
PLoS computational biology Volume 4 (2008) p.e1000052

Evolvability and hierarchy in rewired bacterial gene networks.
Isalan M, Lemerle C, Michalodimitrakis K, Horn C, Beltrao P, Raineri E, Garriga-Canut M, Serrano L.
Nature Volume 452 (2008) p.840-845

2007

Structures in systems biology.
Beltrao P, Kiel C, Serrano L.
Current opinion in structural biology Volume 17 (2007) p.378-384

A genome-wide Ras-effector interaction network.
Kiel C, Foglierini M, Kuemmerer N, Beltrao P, Serrano L.
Journal of molecular biology Volume 370 (2007) p.1020-1032

Specificity and evolvability in eukaryotic protein interaction networks.
Beltrao P, Serrano L.
PLoS computational biology Volume 3 (2007) p.e25

2005

Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions.
Beltrao P, Serrano L.
PLoS computational biology Volume 1 (2005) p.e26

2004

SmartCell, a framework to simulate cellular processes that combines stochastic approximation with diffusion and localisation: analysis of simple networks.
Ander M, Beltrao P, Di Ventura B, Ferkinghoff-Borg J, Foglierini M, Kaplan A, Lemerle C, Tomás-Oliveira I, Serrano L.
Systems biology Volume 1 (2004) p.129-138

2003

Comparative evolutionary genomics unveils the molecular mechanism of reassignment of the CTG codon in Candida spp.
Massey SE, Moura G, Beltrão P, Almeida R, Garey JR, Tuite MF, Santos MA.
Genome research Volume 13 (2003) p.544-557