Team Leader: UniProt development
BSc In Veterinary Medicine. PhD in Molecular Biology (Bioinformatics), 2003. At EMBL-EBI since 1996. Team Leader since 2009.
martin [at] ebi.ac.uk
ORCID iD: 0000-0001-5454-2815
Tel:+44 (0)1223 494 408 / Fax:+44 (0)1223 494 468
Maria Martin's team provides the bioinformatics infrastructure for the databases and services of the Universal Protein Resource (UniProt). The team comprises software engineers and bioinformaticians who are responsible for the UniProt and Gene Ontology Annotation software and database development, and who study novel automatic methods for protein annotation and representation. The team's user experience analyst coordinates the user request gathering process, which informs the design and development of the web site. The team is also responsible for the maintenance and development of tools for UniProt curation.
Maria's team works in a fully complementary fashion with Claire O'Donovan's UniProt Content team to provide essential resources for the biological community, as the databases have become an integral part of the tools researchers use on a daily basis for their work.
UniProt is a comprehensive resource for protein sequence and functional annotation data, and comprises four major components, each optimized for different uses:
- The UniProt Knowledgebase (UniProtKB) is an expertly curated database, a central access point for integrated protein information with cross-references to multiple sources. The UniProt GO annotation (GOA) program adds high-quality Gene Ontology annotations to proteins in UniProtKB.
- The UniProt Archive (UniParc) is a comprehensive sequence repository, reflecting the history of all protein sequences.
- UniProt Reference Clusters (UniRef) merge closely related sequences based on sequence identity to speed up searches.
- The UniProt Metagenomic and Environmental Sequences database (UniMES) responds to the expanding area of metagenomic data.