Irene Papatheodorou

Irene Papatheodorou

Expression Atlas Content Project Leader - Petryszak team: Gene Expression

ORCID iD: 0000-0001-7270-5470

Tel:+ 44 (0) 1223 49 2568 / Fax:+ 44 (0) 1223 48 46 96



Linking gene expression to phenotypes via pathway information.
Papatheodorou I, Oellrich A, Smedley D.
Journal of biomedical semantics Volume 6 (2015) p.17

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.
Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde OC, Yuan Y, Ng CK, Dunning MJ, Dicks E, Provenzano E, Sammut S, McKinney S, Ellis IO, Pinder S, Purushotham A, Murphy LC, Kristensen VN, METABRIC Group, Brenton JD, Pharoah PD, Børresen-Dale AL, Aparicio S, Caldas C.
Molecular oncology Volume 9 (2015) p.115-127


Comparison of the mammalian insulin signalling pathway to invertebrates in the context of FOXO-mediated ageing.
Papatheodorou I, Petrovs R, Thornton JM.
Bioinformatics (Oxford, England) Volume 30 (2014) p.2999-3003

Using association rule mining to determine promising secondary phenotyping hypotheses.
Oellrich A, Jacobsen J, Papatheodorou I, Sanger Mouse Genetics Project, Smedley D.
Bioinformatics (Oxford, England) Volume 30 (2014) p.i52-59

Interplay of dFOXO and two ETS-family transcription factors determines lifespan in Drosophila melanogaster.
Alic N, Giannakou ME, Papatheodorou I, Hoddinott MP, Andrews TD, Bolukbasi E, Partridge L.
PLoS genetics Volume 10 (2014) p.e1004619

MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans.
Riesen M, Feyst I, Rattanavirotkul N, Ezcurra M, Tullet JM, Papatheodorou I, Ziehm M, Au C, Gilliat AF, Hellberg J, Thornton JM, Gems D.
Aging Volume 6 (2014) p.98-117

DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.
Tullet JM, Araiz C, Sanders MJ, Au C, Benedetto A, Papatheodorou I, Clark E, Schmeisser K, Jones D, Schuster EF, Thornton JM, Gems D.
PLoS genetics Volume 10 (2014) p.e1004109


Transcriptional feedback in the insulin signalling pathway modulates ageing in both Caenorhabditis elegans and Drosophila melanogaster.
Ivanov DK, Papatheodorou I, Ziehm M, Thornton JM.
Molecular bioSystems Volume 9 (2013) p.1756-1764


The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.
Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, McKinney S, METABRIC Group, Langerød A, Green A, Provenzano E, Wishart G, Pinder S, Watson P, Markowetz F, Murphy L, Ellis I, Purushotham A, Børresen-Dale AL, Brenton JD, Tavaré S, Caldas C, Aparicio S.
Nature Volume 486 (2012) p.346-352

Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing.
Papatheodorou I, Ziehm M, Wieser D, Alic N, Partridge L, Thornton JM.
PloS one Volume 7 (2012) p.e50881


Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling.
Alic N, Andrews TD, Giannakou ME, Papatheodorou I, Slack C, Hoddinott MP, Cochemé HM, Schuster EF, Thornton JM, Partridge L.
Molecular systems biology Volume 7 (2011) p.502

Computational biology for ageing.
Wieser D, Papatheodorou I, Ziehm M, Thornton JM.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Volume 366 (2011) p.51-63


A metadata approach for clinical data management in translational genomics studies in breast cancer.
Papatheodorou I, Crichton C, Morris L, Maccallum P, METABRIC Group, Davies J, Brenton JD, Caldas C.
BMC medical genomics Volume 2 (2009) p.66


Visualization of microarray results to assist interpretation.
Papatheodorou I, Sergot M, Randall M, Stewart GR, Robertson BD.
Tuberculosis (Edinburgh, Scotland) Volume 84 (2004) p.275-281


Inference of gene relations from microarray experiments by abductive reasoning.
Papatheodorou IV.
Volume (0) p.