Felix Kruger

Felix Kruger

Visitor - Overington research group

ORCID iD: 0000-0002-6054-5622

Tel: / Fax:+ (0) 1223 494 468

Publications

2014

The ChEMBL bioactivity database: an update.
Bento AP, Gaulton A, Hersey A, Bellis LJ, Chambers J, Davies M, Krüger FA, Light Y, Mak L, McGlinchey S, Nowotka M, Papadatos G, Santos R, Overington JP.
Nucleic Acids Res Volume 42 (2014) p.d1083-90
DOI: 10.1093/nar/gkt1031

2012

Global analysis of small molecule binding to related protein targets.
Kruger FA, Overington JP.
PLoS Comput Biol Volume 8 (2012) p.e1002333
DOI: 10.1371/journal.pcbi.1002333

Mapping small molecule binding data to structural domains.
Kruger FA, Rostom R, Overington JP.
BMC Bioinformatics Volume 13 Suppl 17 (2012) p.s11
DOI: 10.1186/1471-2105-13-s17-s11

2011

Collation and data-mining of literature bioactivity data for drug discovery.
Bellis LJ, Akhtar R, Al-Lazikani B, Atkinson F, Bento AP, Chambers J, Davies M, Gaulton A, Hersey A, Ikeda K, Krüger FA, Light Y, McGlinchey S, Santos R, Stauch B, Overington JP.
Biochem Soc Trans Volume 39 (2011) p.1365-1370
DOI: 10.1042/bst0391365

2009

Fragment formal concept analysis accurately classifies compounds with closely related biological activities.
Krüger F, Lounkine E, Bajorath J.
ChemMedChem Volume 4 (2009) p.1174-1181
DOI: 10.1002/cmdc.200900035