Registry

Total: 128,781,227 Interactions from 36 PSICQUIC Services, of which 9 are currently down.

Filter:

Name Status Interactions Version URLs Description Restricted Tags
APID Interactomes
Active
1,225,163
1.1.5
SOAP: http://cicblade.dep.usal.es/psicquic-ws/webservices/psicquic
REST: http://cicblade.dep.usal.es/psicquic-ws/webservices/current/search/

REST example

NO
protein-protein
imported
spoke expansion
clustered  

BioGrid
Active
1,384,042
1.3.9
SOAP: http://tyersrest.tyerslab.com:8805/psicquic/webservices/psicquic
REST: http://tyersrest.tyerslab.com:8805/psicquic/webservices/current/search/

REST example

NO
protein-protein
internally-curated
rapid curation
spoke expansion
evidence  

bhf-ucl
Active
2,632
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/bhf-ucl/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/bhf-ucl/webservices/current/search/

REST example

NO
protein-protein
smallmolecule-protein
nucleicacid-protein
internally-curated
imex curation
mimix curation
spoke expansion
evidence  

ChEMBL
Active
628,504
1.2.7
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/chembl/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/chembl/webservices/current/search/

REST example

NO
smallmolecule-protein
internally-curated
mimix curation
spoke expansion
evidence  

DIP
Active
104,965
1.3
SOAP: http://imex.mbi.ucla.edu/xpsq-dip-all/service/soap/current
REST: http://imex.mbi.ucla.edu/xpsq-dip-all/service/rest/current/search/

REST example

NO
protein-protein
internally-curated
imex curation
mimix curation
spoke expansion
evidence  

DIP-IMEx
Inactive
0
-
SOAP: http://imex.mbi.ucla.edu/xpsq-dip-imex/service/soap/current
REST: http://imex.mbi.ucla.edu/xpsq-dip-imex/service/rest/current/search/

REST example

NO
protein-protein
internally-curated
imex curation
mimix curation
spoke expansion
evidence  

HPIDb
Active
4,519
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/hpidb/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/hpidb/webservices/current/search/

REST example

NO
protein-protein
internally-curated
mimix curation
spoke expansion
evidence  

InnateDB
Active
33,295
1.3.9
SOAP: http://psicquic.curated.innatedb.com/webservices/psicquic
REST: http://psicquic.curated.innatedb.com/webservices/current/search/

REST example
This service queries all interactions that have been manually annotated to MIMIx standards by the InnateDB curation team.
NO
protein-protein
internally-curated
spoke expansion
mimix curation
evidence
nucleicacid-protein  

InnateDB-All
Active
443,375
1.3.9
SOAP: http://psicquic.all.innatedb.com/webservices/psicquic
REST: http://psicquic.all.innatedb.com/webservices/current/search/

REST example
This service queries all interactions in InnateDB including both interactions curated by the InnateDB curation team and those integrated from other databases.
NO
protein-protein
internally-curated
spoke expansion
mimix curation
evidence
nucleicacid-protein  

IntAct
Active
587,686
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/intact/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/intact/webservices/current/search/

REST example
Detailed curation of experimentally verified interaction evidences extracted from the literature or directly submitted by authors as part of the publication process.
NO
protein-protein
smallmolecule-protein
nucleicacid-protein
internally-curated
imported
imex curation
mimix curation
spoke expansion
evidence  

mentha
Active
1,144,545
1.3.13
SOAP: http://mentha.uniroma2.it:9090/psicquic/webservices/psicquic
REST: http://mentha.uniroma2.it:9090/psicquic/webservices/current/search/

REST example

NO
protein-protein
imported
clustered
spoke expansion  

MPIDB
Active
1,759
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/mpidb/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/mpidb/webservices/current/search/

REST example

NO
protein-protein
internally-curated
imex curation
spoke expansion
evidence  

iRefIndex
Inactive
0
-
SOAP: http://psicquic.irefindex.org/psicquic/webservices/psicquic
REST: http://psicquic.irefindex.org/psicquic/webservices/current/search/

REST example

NO
protein-protein
imported
bipartite expansion
evidence  

MatrixDB
Active
1,342
1.3.13
SOAP: http://matrixdb.univ-lyon1.fr:8080/psicquic/webservices
REST: http://matrixdb.univ-lyon1.fr:8080/psicquic/webservices/current/search/

REST example
MatrixDB focuses on interactions established by extracellular matrix proteins, proteoglycans and polysaccharides. This service queries experimentally-supported interactions curated from the literature by the MatrixDB curation team.
NO
protein-protein
smallmolecule-protein
internally-curated
imex curation
mimix curation
spoke expansion
evidence  

MINT
Active
135,588
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/mint/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/mint/webservices/current/search/

REST example

NO
protein-protein
internally-curated
imex curation
mimix curation
spoke expansion
evidence  

Reactome
Active
141,996
1.2.7
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/reactome/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/reactome/webservices/current/search/

REST example

NO
protein-protein
predicted
evidence  

Reactome-FIs
Active
209,988
1.2.7
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/reactome-fi/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/reactome-fi/webservices/current/search/

REST example

NO
protein-protein
predicted
imported
clustered  

STRING
Inactive
0
-
SOAP: http://string.uzh.ch/psicquic/webservices/psicquic
REST: http://string.uzh.ch/psicquic/webservices/current/search/

REST example

NO
protein-protein
predicted
imported
spoke expansion
clustered  

BIND
Inactive
0
-
SOAP: http://webservice.baderlab.org:8480/psicquic-ws/webservices/psicquic
REST: http://webservice.baderlab.org:8480/psicquic-ws/webservices/current/search/

REST example

NO
protein-protein
smallmolecule-protein
nucleicacid-protein
spoke expansion
clustered  

Interoporc
Inactive
0
-
SOAP: http://webservice.baderlab.org:8580/psicquic-interoporc-ws/webservices/psicquic
REST: http://webservice.baderlab.org:8580/psicquic-interoporc-ws/webservices/current/search/

REST example

NO
protein-protein
predicted
evidence  

DrugBank
Inactive
0
-
SOAP: http://psicquic.wishartlab.com/psicquic-ws/webservices/psicquic
REST: http://psicquic.wishartlab.com/psicquic-ws/webservices/current/search/

REST example

NO
smallmolecule-protein
internally-curated
mimix curation
evidence  

EBI-GOA-miRNA
Active
2,071
1.3.13
SOAP: http://www.ebi.ac.uk/QuickGO/psicquic-rna/webservices/psicquic
REST: http://www.ebi.ac.uk/QuickGO/psicquic-rna/webservices/current/search/

REST example

NO
nucleicacid-gene
rapid curation
experimentally-observed  

I2D
Active
817,915
1.1.6
SOAP: http://ophid.utoronto.ca/psicquic-ws/webservices/psicquic
REST: http://ophid.utoronto.ca/psicquic-ws/webservices/current/search/

REST example

NO
protein-protein
internally-curated
evidence  

I2D-IMEx
Active
1,118
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/i2d/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/i2d/webservices/current/search/

REST example

NO
protein-protein
nucleicacid-protein
smallmolecule-protein
internally-curated
imex curation
evidence
spoke expansion  

InnateDB-IMEx
Active
855
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/innatedb/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/innatedb/webservices/current/search/

REST example
This service queries interactions that have been manually annotated to IMEx standards by the InnateDB curation team.
NO
protein-protein
nucleicacid-protein
smallmolecule-protein
internally-curated
imex curation
evidence
spoke expansion  

MolCon
Active
495
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/molcon/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/molcon/webservices/current/search/

REST example

NO
protein-protein
nucleicacid-protein
smallmolecule-protein
internally-curated
imex curation
evidence
spoke expansion  

UniProt
Active
15,046
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/uniprot/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/uniprot/webservices/current/search/

REST example

NO
protein-protein
nucleicacid-protein
smallmolecule-protein
internally-curated
imex curation
evidence
spoke expansion
mimix curation  

MBInfo
Active
638
1.3.13
SOAP: http://www.ebi.ac.uk/Tools/webservices/psicquic/mbinfo/webservices/psicquic
REST: http://www.ebi.ac.uk/Tools/webservices/psicquic/mbinfo/webservices/current/search/

REST example

NO
protein-protein
nucleicacid-protein
smallmolecule-protein
internally-curated
imex curation
evidence
spoke expansion  

BindingDB
Active
1,011,029
v1.3
SOAP: http://bindingdb.org/psicquic-ws
REST: http://bindingdb.org/psicquic-ws/webservices/psicquic/current/search/

REST example

NO
smallmolecule-protein
internally-curated
evidence
spoke expansion
experimentally-observed  

VirHostNet
Active
50,146
1.3.13
SOAP: http://virhostnet.prabi.fr:9090/psicquic/webservices/psicquic
REST: http://virhostnet.prabi.fr:9090/psicquic/webservices/current/search/

REST example

NO
protein-protein
evidence
internally-curated
clustered
rapid curation
experimentally-observed
imported
spoke expansion  

TopFind
Inactive
0
-
SOAP: http://clipserve.clip.ubc.ca/topfind-psicquic-ws/psicquic
REST: http://clipserve.clip.ubc.ca/topfind-psicquic-ws/current/search/

REST example

NO
protein-protein
evidence
internally-curated
predicted  

Spike
Inactive
0
1.2.0
SOAP: http://spike.cs.tau.ac.il/psicquic-ws/webservices
REST: http://spike.cs.tau.ac.il/psicquic-ws/webservices/current/search/

REST example

NO
protein-protein
evidence
internally-curated  

GeneMANIA
Inactive
120,644,180
1.2.3
SOAP: http://webservice.baderlab.org:8380/psi-gm/webservices/psicquic
REST: http://webservice.baderlab.org:8380/psi-gm/webservices/current/search/

REST example

NO
protein-protein
predicted
imported  

BAR
Active
104,854
1.3.11
SOAP: http://bar.utoronto.ca:9090/psicquic/webservices/psicquic
REST: http://bar.utoronto.ca:9090/psicquic/webservices/current/search/

REST example

NO
protein-protein
imported
spoke expansion
predicted
internally-curated  

EBI-GOA-nonIntAct
Active
63,670
1.3.13
SOAP: http://www.ebi.ac.uk/QuickGO/psicquic/webservices/psicquic
REST: http://www.ebi.ac.uk/QuickGO/psicquic/webservices/current/search/

REST example

NO
protein-protein
nucleicacid-protein
rapid curation
experimentally-observed  

ZINC
Active
19,811
1.3.13
SOAP: http://psicquic.docking.org/psicquic/webservices/psicquic
REST: http://psicquic.docking.org/psicquic/webservices/current/search/

REST example
ZINC is a database of commercially available compounds for virtual screening. It uses publicly available bioactivity data to allow investigators to access chemical tools for biology.
NO
smallmolecule-protein
internally-curated
experimentally-observed  

About PSICQUIC Registry

The PSICQUIC Registry contains the list of PSICQUIC services available, their tags, and their current status. The registry also shows the number of total binary interactions that each resource has made available through PSICQUIC. For more information about PSICQUIC, please visit the Google Project documentation.