Dbfetch
ID X72794; SV 1; linear; genomic DNA; STD; MUS; 8190 BP. XX AC X72794; XX DT 30-NOV-1993 (Rel. 37, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 6) XX DE M.musculus gene for gelatinase B XX KW gelatinase B. XX OS Mus musculus (house mouse) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. XX RN [1] RX DOI; 10.1111/j.1432-1033.1993.tb18359.x. RX PUBMED; 8243459. RA Masure S., Nys G., Fiten P., Van Damme J., Opdenakker G.; RT "Mouse gelatinase B. cDNA cloning, regulation of expression and RT glycosylation in WEHI-3 macrophages and gene organisation"; RL Eur. J. Biochem. 218(1):129-141(1993). XX RN [2] RP 1-8190 RA Masure S.; RT ; RL Submitted (03-MAY-1993) to the INSDC. RL S. Masure, Rega Inst. for Medical Research, Minderbroedersstraat 10, B-3000 RL Leuven, BELGIUM XX DR MD5; 0865f6a7de9865a9c29a52601f8c1d95. DR Ensembl-Gn; ENSMUSG00000017737; mus_musculus. DR Ensembl-Gn; MGP_129S1SvImJ_G0026883; mus_musculus_129s1svimj. DR Ensembl-Gn; MGP_AJ_G0026850; mus_musculus_aj. DR Ensembl-Gn; MGP_AKRJ_G0026821; mus_musculus_akrj. DR Ensembl-Gn; MGP_BALBcJ_G0026859; mus_musculus_balbcj. DR Ensembl-Gn; MGP_C3HHeJ_G0026601; mus_musculus_c3hhej. DR Ensembl-Gn; MGP_C57BL6NJ_G0027306; mus_musculus_c57bl6nj. DR Ensembl-Gn; MGP_CASTEiJ_G0026059; mus_musculus_casteij. DR Ensembl-Gn; MGP_CBAJ_G0026578; mus_musculus_cbaj. DR Ensembl-Gn; MGP_DBA2J_G0026716; mus_musculus_dba2j. DR Ensembl-Gn; MGP_FVBNJ_G0026682; mus_musculus_fvbnj. DR Ensembl-Gn; MGP_LPJ_G0026818; mus_musculus_lpj. DR Ensembl-Gn; MGP_NODShiLtJ_G0026701; mus_musculus_nodshiltj. DR Ensembl-Gn; MGP_NZOHlLtJ_G0027363; mus_musculus_nzohlltj. DR Ensembl-Gn; MGP_PWKPhJ_G0025796; mus_musculus_pwkphj. DR Ensembl-Gn; MGP_WSBEiJ_G0026132; mus_musculus_wsbeij. DR Ensembl-Tr; ENSMUST00000017881; mus_musculus. DR Ensembl-Tr; MGP_129S1SvImJ_T0059233; mus_musculus_129s1svimj. DR Ensembl-Tr; MGP_AJ_T0059259; mus_musculus_aj. DR Ensembl-Tr; MGP_AKRJ_T0059205; mus_musculus_akrj. DR Ensembl-Tr; MGP_BALBcJ_T0059192; mus_musculus_balbcj. DR Ensembl-Tr; MGP_C3HHeJ_T0058891; mus_musculus_c3hhej. DR Ensembl-Tr; MGP_C57BL6NJ_T0059664; mus_musculus_c57bl6nj. DR Ensembl-Tr; MGP_CASTEiJ_T0059162; mus_musculus_casteij. DR Ensembl-Tr; MGP_CBAJ_T0058862; mus_musculus_cbaj. DR Ensembl-Tr; MGP_DBA2J_T0058966; mus_musculus_dba2j. DR Ensembl-Tr; MGP_FVBNJ_T0058947; mus_musculus_fvbnj. DR Ensembl-Tr; MGP_LPJ_T0059077; mus_musculus_lpj. DR Ensembl-Tr; MGP_NODShiLtJ_T0058925; mus_musculus_nodshiltj. DR Ensembl-Tr; MGP_NZOHlLtJ_T0059849; mus_musculus_nzohlltj. DR Ensembl-Tr; MGP_PWKPhJ_T0058730; mus_musculus_pwkphj. DR Ensembl-Tr; MGP_WSBEiJ_T0058170; mus_musculus_wsbeij. DR EuropePMC; PMC1602302; 15632000. DR EuropePMC; PMC409857; 10587514. XX FH Key Location/Qualifiers FH FT source 1..8190 FT /organism="Mus musculus" FT /strain="C57 Black/6" FT /mol_type="genomic DNA" FT /dev_stage="1 year" FT /clone="MMG1" FT /tissue_type="liver" FT /db_xref="taxon:10090" FT misc_feature 573..578 FT /note="SP1 box" FT misc_feature 639..648 FT /note="NF-kappa-B element" FT misc_feature 695..701 FT /note="AP-1 box" FT misc_feature 716..721 FT /note="SP1 box" FT repeat_region 1040..1089 FT /note="CA repeat region" FT misc_feature 1093..1099 FT /note="AP-1 box" FT misc_feature 1119..1124 FT /note="SP1 box" FT regulatory 1152..1156 FT /regulatory_class="TATA_box" FT CDS join(1200..1340,1778..2007,2226..2374,2652..2780, FT 2890..3063,3244..3417,3768..3944,4050..4205,5361..5694, FT 5796..5935,6205..6355,6460..6563,7714..7847) FT /gene="MMP-9" FT /product="gelatinase b" FT /EC_number="3.4.24.35" FT /db_xref="GOA:P41245" FT /db_xref="InterPro:IPR000562" FT /db_xref="InterPro:IPR000585" FT /db_xref="InterPro:IPR001818" FT /db_xref="InterPro:IPR002477" FT /db_xref="InterPro:IPR006026" FT /db_xref="InterPro:IPR006970" FT /db_xref="InterPro:IPR013806" FT /db_xref="InterPro:IPR018486" FT /db_xref="InterPro:IPR018487" FT /db_xref="InterPro:IPR021158" FT /db_xref="InterPro:IPR021190" FT /db_xref="InterPro:IPR024079" FT /db_xref="InterPro:IPR033739" FT /db_xref="InterPro:IPR036365" FT /db_xref="InterPro:IPR036366" FT /db_xref="InterPro:IPR036375" FT /db_xref="InterPro:IPR036943" FT /db_xref="MGI:MGI:97011" FT /db_xref="UniProtKB/Swiss-Prot:P41245" FT /protein_id="CAA51314.1" FT /translation="MSPWQPLLLALLAFGCSSAAPYQRQPTFVVFPKDLKTSNLTDTQL FT AEAYLYRYGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGELDSQTLKAIRTPRCGVPD FT VGRFQTFKGLKWDHHNITYWIQNYSEDLPRDMIDDAFARAFAVWGEVAPLTFTRVYGPE FT ADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGAGVQGDAHFDDDELWSLGKGVVIPTYY FT GNSNGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDGKFGFCPSERLYTEHG FT NGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWCATTANYDQDKLYGFCPTRVDATVVGG FT NSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWGFCPDQGYSLFLVA FT AHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKDDIDGIQYLYGRGSKPDPRPPATTT FT TEPQPTAPPTMCPTIPPTAYPTVGPTVGPTGAPSPGPTSSPSPGPTGAPSPGPTAPPTA FT GSSEASTESLSPADNPCNVDVFDAIAEIQGALHFFKDGWYWKFLNHRGSPLQGPFLTAR FT TWPALPATLDSAFEDPQTKRVFFFSGRQMWVYTGKTVLGPRSLDKLGLGPEVTHVSGLL FT PRRLGKALLFSKGRVWRFDLKSQKVDPQSVIRVDKEFSGVPWNSHDIFQYQDKAYFCHG FT KFFWRVSFQNEVNKVDHEVNQVDDVGYVTYDLLQCP" FT mRNA join(<1200..1340,1778..2007,2226..2374,2652..2780, FT 2890..3063,3244..3417,3768..3944,4050..4205,5361..5694, FT 5796..5935,6205..6355,6460..6563,7714..>7847) FT /gene="MMP-9" FT exon <1200..1340 FT /number=1 FT intron 1341..1777 FT /number=1 FT exon 1778..2007 FT /number=2 FT intron 2008..2225 FT /number=2 FT exon 2226..2374 FT /number=3 FT intron 2375..2651 FT /number=3 FT exon 2652..2780 FT /number=4 FT intron 2781..2889 FT /number=4 FT exon 2890..3063 FT /number=5 FT intron 3064..3243 FT /number=5 FT exon 3244..3417 FT /number=6 FT intron 3418..3767 FT /number=6 FT exon 3768..3944 FT /number=7 FT intron 3945..4049 FT /number=7 FT exon 4050..4205 FT /number=8 FT intron 4206..5360 FT /number=8 FT exon 5361..5694 FT /number=9 FT intron 5695..5795 FT /number=9 FT exon 5796..5935 FT /number=10 FT intron 5936..6204 FT /number=10 FT exon 6205..6355 FT /number=11 FT intron 6356..6459 FT /number=11 FT exon 6460..6563 FT /number=12 FT intron 6564..7713 FT /number=12 FT exon 7714..>7847 FT /number=13 FT regulatory 8046..8051 FT /regulatory_class="polyA_signal_sequence" XX SQ Sequence 8190 BP; 1773 A; 2250 C; 2244 G; 1923 T; 0 other; gagctcacca gtgagaagca tctaagagaa gcttgggaga acacccagct ctctctctcc 60 ggctcacagg tctgttcgtt gggaagcaca tgaaggtctg ggcacacagg aggcttagtc 120 agaacagctt gctgaagaca gatcaaggcc ctgctccacc atggtggcag gcgaggagga 180 tggaaggccg ggggctgccg gctgttggca agactgtgcc aaagctttcc tgagtggagc 240 agggcagggc tggaggaggg gaagggtcca tgacgatctc acagctcggg agaggaaggt 300 gtttgcccca tccaggtcac cccaaggctt agagccaaga ccccagtctc ctaatttcca 360 atcacaaacc tgacaccatc aactgaggtc tcgtgaacac tgctgaaagt ggtttttctg 420 tgtttcgaga gtctcatttt atcctcagat caatataggg acaaaggctt gagcgacaaa 480 gggtctgttt ttgttcttta aacagaagag gaaggatagt gctagcctga gaaggatgaa 540 gcttctgctt gctcccacat gtgtgtgtcc ccccgccccc caggctcatc tttccttccc 600 caaggagtca gcctgctgga gctaggggtt tgccccatgg aattccccaa atcctgcctc 660 aaagagcctg ctcccagagg ccaggagagg aagctgagtc aaagactcta tcagggggcg 720 gggatgagag gatagaacct acagtgtggg gatgggctcc aggctgcact ctggccaggg 780 agggggtgtc tcagaagccc aaggaagagg ggtctcgggc ctcaggtctc ccagtctttt 840 actgggctga tcagtcaggg ccgtcagacc tagggctagg tgaatgcccc atcctgcaca 900 ccctccttcc ctttcccaca aagtctgcag tttgcagaaa ctaaaccctg agttctgtgg 960 tttcctgtgg gtctgggggt cctgcctgac ttggcaatgg gggactgtgg gcagggcata 1020 agggaggggg tagtgtaaac acacacacac acacacacac acacacacac acacacacac 1080 acacacacac gctgagtcag cataagcctg gaggggaggg gcggggtcac tgattccgtt 1140 ttactgcctc tttaaaatct ctgcaaaggc agcgttagcc agaagctgcg gtcctcacca 1200 tgagtccctg gcagcccctg ctcctggctc tcctggcttt cggctgcagc tctgctgccc 1260 cttaccagcg ccagccgact tttgtggtct tccccaaaga cctgaaaacc tccaacctca 1320 cggacaccca gctggcagag gtagacagat ggctcggtgg atagctgaga agggctggtc 1380 aggaagatgt ccccctctcc caaggaatgg ggcctcagat atgctttctg gatttggggg 1440 tgatgggcat gtctgccagg gttaggcagt agggggtagg tggtctggag gctctgggca 1500 gattcgggtc tgttggaggg acagattggg ttcggcttcg aagggttgtg acatggcgca 1560 ggttggcagt gaacagttaa actctagtgg ggctgagggg taggcatggt ttatatcatc 1620 tgaggtcgag gtgtgatgct gtcctcagga taggggaatt ctagctgtgt aggaagaact 1680 ggtgtcctgg ccgtagagtc cctaagcatg tggcccagag gtccagagcc aaggtgccag 1740 aactctgtga tgtctctgcc ccttcctcca tccacaggca tacttgtacc gctatggtta 1800 cacccgggcc gcccagatga tgggagagaa gcagtctcta cggccggctt tgctgatgct 1860 tcagaagcag ctctccctgc cccagactgg tgagctggac agccagacac taaaggccat 1920 tcgaacacca cgctgtggtg tcccagacgt gggtcgattc caaaccttca aaggcctcaa 1980 gtgggaccat cataacatca catactggtg agatgtcggg ctagaagcag gtgcctgggt 2040 gggactggag gccagtttgc acctccggtt agctgaacac aagggatcct tagcaataca 2100 agttccgaga gaggctgcag ccctgtgtgt tttgaagcga tcgtggtgta gctgctgccc 2160 cgcccacccc catttgtaat ccgtgcatgc ccgatccccc atcgacgctg gcttttcacc 2220 tccaggatcc aaaactactc tgaagacttg ccgcgagaca tgatcgatga cgccttcgcg 2280 cgcgccttcg cggtgtgggg cgaggtggca cccctcacct tcacccgcgt gtacggaccc 2340 gaagcggaca ttgtcatcca gtttggtgtc gcgggtgaga attcccgggc tgggcaggct 2400 atgggaggga cgaccacgga cagagtagaa gggacagcag atctgtccgc tcttatgcct 2460 gccccacaat ccctagtcgc tgcttccaca aatgacctcc cccaaccccc agcggctttg 2520 gagtcgcagt cacctcttct caaagtctgg tgcgctgctc agcgggagac acagtcgctt 2580 tcagtctctt gcccttaaag agagcaaagt gttgctgatt gagtcccttc ctctccgatg 2640 gcctcttgca gagcacggag acgggtatcc cttcgacggc aaggacggcc ttctggcaca 2700 cgcctttccc cctggcgccg gcgttcaggg agatgcccat ttcgacgacg acgagttgtg 2760 gtcgctgggc aaaggcgtcg gtgagatcct gagccttcca gtatccgccc catccccacc 2820 cctgtcccaa ctcccttctc ttacactggt gtgtggccag acgccctgac tctagcctcc 2880 tttctacagt gatccccact tactatggaa actcaaatgg tgccccatgt cactttccct 2940 tcaccttcga gggacgctcc tattcggcct gcaccacaga cggccgcaac gacggcacgc 3000 cttggtgtag cacaacagct gactacgata aggacggcaa atttggtttc tgccctagtg 3060 agagtgagta tgcgctgggg gtggggagcg gggcgccgcc ttgaaggttc cagaatcttc 3120 tttcccagtc tctctttgcc atcagtggtg tggctactcg ccctctccct gggtctggtc 3180 ccctctgtga aatgagacgc atgctggggc cgggcttggc ggtaataccg tgggtctcct 3240 caggactcta cacggagcac ggcaacggag aaggcaaacc ctgtgtgttc ccgttcatct 3300 ttgagggccg ctcctactct gcctgcacca ctaaaggccg ctcggatggt taccgctggt 3360 gcgccaccac agccaactat gaccaggata aactgtatgg cttctgccct acccgaggta 3420 cctctgcccc gcctatcagg gtcagcccgg ctctgctttc cagcattggt ctctaaaggt 3480 ggcttttcca tccattcatt tccttcctct atttaccatc cgccgtctgc ctccacacct 3540 cctctccttg actcccaatt gggcagcctt ttttgtttac ccttaggctt tggtctccaa 3600 tcttagcctc tgcctatcaa tattttccgg cttccgcggt gctccacagc gccccctagg 3660 cttcaaaaac taggccatgg aggatctcta gctcagctta gtttggtcca tccctggcac 3720 catattagat ccacccatct ggctcacttg attcttggtc tctccagtgg acgcgaccgt 3780 agttgggggc aactcggcag gagagctgtg cgtcttcccc ttcgtcttcc tgggcaagca 3840 gtactcttcc tgtaccagcg acggccgcag ggatgggcgc ctctggtgtg cgaccacatc 3900 gaacttcgac actgacaaga agtggggttt ctgtccagac caaggtgagc ggggcactga 3960 ggctcctggg gtggggcctg agtcacctcc tggcagtcaa ggcggagcag ccagggctgg 4020 tggcatttca gactccttct accttccagg gtacagcctg ttcctggtgg cagcgcacga 4080 gttcggccat gcactgggct tagatcattc cagcgtgccg gaagcgctca tgtacccgct 4140 gtatagctac ctcgagggct tccctctgaa taaagacgac atagacggca tccagtatct 4200 gtatggtgag gctgggggac agagacgagg agcagagaga aggatgtggc tcagctgtag 4260 gaagaggaga ggggagaaac ggaacctcaa tatctatctg ggtcagggcc tgagtgccca 4320 gtaagtggag atggcactct aggcccgggt tcaaaagcca gcccagggct gggtgtgcag 4380 cctagtggtt agattacata ctgaatgatg caaagcagac atgaggccct gcgtttgatc 4440 ctcctcagca agaagggtca gccaagccac ttcataggtg aacttagtta ggtgtgtcac 4500 ttccctccca tataaagtgg cggcgtgcga taatagcgtg gctctcataa ggctttgata 4560 gggttaactg aagtagaatg atgcctgact ttattaagtg acatttgatt gtcttgtctt 4620 gtttttgatc atcattaacc tttgaaaaat ggggatattt gctgggtggt ggcatagcaa 4680 gcttgtgatc ccagaacccg gggggattgc gacaaaaaag ttaccatgag ttttaggcta 4740 gcctgagcga tacactaagc tccaggccaa cctgggctac ttaaagctct gacccaaagg 4800 aacttccaaa gattagttga tttatatttc tatgggtgtt ttgcctgaat gtatgtgcac 4860 aaggtatgtg caatgccagc agaggccaga agagggcgtc agatcactta ggactggaga 4920 agcagattgt tgttagctgc catgtgggta ttgggaaatg aacccaggtc ctctggaaga 4980 gcagccagtg gtcttaatta actattgagc catgtcttca gcccccaaag gagcttttaa 5040 aggcatagca ggccaggaat gtttgccctt aggagtcaga ggcagctcac agcactgttt 5100 gacacagtgg tcacccaaaa gactctctcc ctgcctgact cgggaaggag ggacattctg 5160 cctgttcggt cctgagaacc cagtccatat cttcacagag ctcagttctg gacacttagg 5220 cttggcatat gagaagaggc ttgctgcgtg tagcctctag cttcaaggga agactgaagg 5280 caccattgct gggcttggtg gtaggctggg gctacagaga aatgctgact agtgtgtctt 5340 atctagtgtc ttgtttttag gtcgtggctc taagcctgac ccaaggcctc cagccaccac 5400 cacaactgaa ccacagccga cagcacctcc cactatgtgt cccactatac ctcccacggc 5460 ctatcccaca gtgggcccca cggttggccc tacaggcgcc ccctcacctg gccccacaag 5520 cagcccgtca cctggcccta caggcgcccc ctcacctggc cctacagcgc cccctactgc 5580 gggctcttct gaggcctcta cagagtcttt gagtccggca gacaatcctt gcaatgtgga 5640 tgtttttgat gctattgctg agatccaggg cgctctgcat ttcttcaagg acgggtaagc 5700 agggagggtg tgtgggtgag agagggggtt tggagaggat cctgcttgcg tcttccacca 5760 actttctcgg gccctgatat ttcctttctt ctcagttggt actggaagtt cctgaatcat 5820 agaggaagcc cattacaggg ccccttcctt actgcccgca cgtggccagc cctgcctgca 5880 acgctggact ccgcctttga ggatccgcag accaagaggg ttttcttctt ctctggttag 5940 tttgtgcccc tctagctcat cgatccctca gtatccgtca gcttaggaca gacacctagt 6000 gtaacccgtg aaactgcgac tccaaaagag cgcccctgcc cagctgataa gatttgacat 6060 tggggggacg gacggacgga cggacggtac tgaattgcaa ttccccttga gtagctctga 6120 tacttagctt ctctggctcc tgcctcctgc ccttcaaaga gactgtgcca caccttagtg 6180 tctactgacc cttctcttcc gcaggacgtc aaatgtgggt gtacacaggc aagaccgtgc 6240 tgggccccag gagtctggat aagttgggtc taggcccaga ggtaacccac gtcagcgggc 6300 ttctcccgcg tcgtctcggg aaggctctgc tgttcagcaa ggggcgtgtc tggaggtaag 6360 agcgaccgag gccaccagta gggggagccc tagcgccact ctcccgcagc tctggggtgg 6420 ggagcgggag aggctcatcg cttgtccacc ttcctgcaga ttcgacttga agtctcagaa 6480 ggtggatccc cagagcgtca ttcgcgtgga taaggagttc tctggtgtgc cctggaactc 6540 acacgacatc ttccagtacc aaggtgaggg ctgctgaggc tggccgggaa gggtcccttc 6600 gtgaaatgtc tcccacactg gactccctct cttagcgact ggctagtttc tcagcaggag 6660 agagcaagcc cttggagatt gaagggaatg ttctagataa gagccatata gagagcaccc 6720 caagttcaca cagcccggac ctaaggtccg gattgcttgc atatcattct tttccgggaa 6780 ctccagtaga gaacgcagct ctctagaagg ctcgttcctt gattattaaa cagtagccaa 6840 gggcctataa tgtgcaggac tgccactagg gatacgtgga gaggcaagaa agtgtctttg 6900 ggcaagtcac tacctctctt ggggcctcag tttccccatc tgtaaaatgt attatctgga 6960 gctctgttag gctaattcaa aggctcaaac ctcccaaatg tattattttt cagccatctc 7020 ctttataccc ttccctccaa ccataccggt aacccagtaa cctttaatat attcttcaag 7080 agtggggagg gttaggagag gagggcagag gttctgactg tgaccccaaa cgatacgaag 7140 gtagaagaaa ctcacacggc cttgcctgtg tgtccaagtt ctcgtctcct ccccgttctc 7200 ttgacatcct ccgtgctcca ccgaggctgg ctgctctttg aacagatcaa ggtcctccat 7260 cccttaaggt cttcgggccc gttgtcccct atttggaaga cttcccactt aaactgtcac 7320 cgggctgcct ctcttcaggc aaaggagaag atttaattgg ggctggctta caggtcagag 7380 gctcagtcca ttattttcat ggtgggaaac gaggtggcac acaggcaaac gtggtgttgg 7440 agaggtagct gagagctcta cctcagcagc aggcagcaag aagagagaga cactgggctt 7500 ggcgtgaaca tctgaaatct caaagcccac cctagtgaca caggtcctcc aataaggcca 7560 caccccctcc cacctcataa gtgccactcc ctatgggcct atagggtcca ttttcattca 7620 aaccaccaca ggtgcttgta aaaatcttgt tccttttgtc aatgatgagg gagcagagga 7680 ctcagctttc ttgtgtgttc ttgtttcccg tagacaaagc ctatttctgc catggcaaat 7740 tcttctggcg tgtgagtttc caaaatgagg tgaacaaggt ggaccatgag gtgaaccagg 7800 tggacgacgt gggctacgtg acctacgacc tcctgcagtg cccttgaact agggctcctt 7860 ctttgcttca accgtgcagt gcaagtctct agagaccacc accaccacca ccacacacaa 7920 accccatccg agggaaaggt gctagctggc caggtacaga ctggtgatct cttctagaga 7980 ctgggaagga gtggaggcag gcagggctct ctctgcccac cgtcctttct tgttggactg 8040 tttctaataa acacggatcc ccaacctttt ccagctactt tagtcaatca gcttatctgt 8100 agttgcagat gcatccgagc aagaagacaa ctttgtaggg tggattctga ccttttattt 8160 ttgtgtggcg tctgagaatt gaatcagctg 8190 //