Dbfetch

ID   X69600; SV 1; linear; genomic DNA; STD; HUM; 291 BP.
XX
AC   X69600;
XX
DT   07-APR-1993 (Rel. 35, Created)
DT   10-NOV-2006 (Rel. 89, Last updated, Version 13)
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DE   Homo sapiens regulatory region for HLA-DRB1 gene, HLA-DRB1*0801 allele
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KW   class II genes; histocompatibility complex; HLA-DR Beta1;
KW   HLA-DRB1*0801 gene; promoter; transcription regulation.
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OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
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RN   [1]
RP   1-291
RA   Louis P.;
RT   ;
RL   Submitted (13-JUL-1992) to the INSDC.
RL   P. Louis, University Hospital / INSERM U291, Laboratoire d'Immunologie,
RL   Hopital Saint Eloi, 34059 Montpellier Cedex, FRANCE
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RN   [2]
RP   1-203
RA   Eliaou J.F.;
RT   "Polymorphism in the regulatory region of the HLA-DRB genes correlating
RT   with ancestral haplotype evolution";
RL   Unpublished.
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DR   MD5; dc6e81b76b0aeea178d9022806d6dc6a.
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FH   Key             Location/Qualifiers
FH
FT   source          1..291
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.3; HGML_LOCUS_UID=LVOO63D"
FT                   /isolate="homozygous typing cell work shop number 9068"
FT                   /mol_type="genomic DNA"
FT                   /cell_line="BM9 WSNO:9068"
FT                   /cell_type="homozygous typing cells ws 9068"
FT                   /tissue_type="cultured B-lymphocytes"
FT                   /germline
FT                   /db_xref="taxon:9606"
FT   regulatory      1..141
FT                   /note="proximal"
FT                   /regulatory_class="promoter"
FT   misc_feature    15..29
FT                   /note="X box"
FT   misc_feature    49..58
FT                   /note="Y box"
FT   regulatory      75..80
FT                   /regulatory_class="CAAT_signal"
FT   regulatory      112..117
FT                   /regulatory_class="TATA_box"
FT   misc_feature    141
FT                   /note="CAP site"
FT   exon            <204..>291
FT                   /gene="HLA-DRB1"
FT                   /allele="HLA-DRB1*0801"
FT                   /product="MHC class II antigen"
FT                   /note="HLA-DR Beta1"
FT   CDS             204..>291
FT                   /gene="HLA-DRB1"
FT                   /allele="HLA-DRB1*0801"
FT                   /product="MHC class II antigen"
FT                   /note="HLA-DR Beta1"
FT                   /db_xref="UniProtKB/TrEMBL:A0N9E2"
FT                   /protein_id="CAL69445.1"
FT                   /translation="MVCLRLPGGSCMAVLTVTLMVLSSPLALA"
FT   sig_peptide     204..290
FT                   /gene="HLA-DRB1"
FT                   /allele="HLA-DRB1*0801"
FT   mat_peptide     291..>291
FT                   /gene="HLA-DRB1"
FT                   /allele="HLA-DRB1*0801"
FT                   /product="MHC class II antigen"
FT                   /note="HLA-DR Beta1"
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SQ   Sequence 291 BP; 58 A; 78 C; 74 G; 81 T; 0 other;
     catacagcat ctctgaccag caactgatga tgctattgaa ctcagatgct gattcgttct        60
     ccaacactag tttacccaat ccaggagcaa ggaaatcagt aacttactcc ctataacttg       120
     gaatgtgggt ggaggggttc atagttctcc ctgagtgaga cttgcctgct gctctggccc       180
     ctggtcctgt cctgttctcc agcatggtgt gtctgaggct ccctggaggc tcctgcatgg       240
     cagttctgac agtgacactg atggtgctga gctccccact ggctttggct g                291
//