Dbfetch

ID   X64546; SV 1; linear; genomic DNA; STD; HUM; 291 BP.
XX
AC   X64546;
XX
DT   19-APR-1993 (Rel. 35, Created)
DT   10-NOV-2006 (Rel. 89, Last updated, Version 12)
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DE   Homo sapiens HLA-DRB1 1502 DNA, HLA-DRB1*1502 allele
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KW   HLA-DR Beta; HLA-DRB genes; major histocompatibility complex;
KW   major histocompatibility complex class II; promoter region.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-291
RA   Louis P.;
RT   ;
RL   Submitted (11-FEB-1992) to the INSDC.
RL   P. Louis, University Hospital / INSERM U291, Lab d'Immunologie, Hopital
RL   Saint Eloi, 34059 Montpellier Cedex, FRANCE
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RN   [4]
RP   1-291
RX   DOI; 10.1007/BF00216386.
RX   PUBMED; 8462990.
RA   Louis P., Eliaou J.F., Kerlan-Candon S., Pinet V., Vincent R.D., Clot J.;
RT   "Polymorphism in the regulatory region of HLA-DRB genes correlating with
RT   haplotype evolution";
RL   Immunogenetics 38(1):21-26(1993).
XX
DR   MD5; 1be0873bef3bdc12c7468e858f8340a6.
DR   EPD; EP73738; HS_HLA-DRB1.
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FH   Key             Location/Qualifiers
FH
FT   source          1..291
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.3"
FT                   /mol_type="genomic DNA"
FT                   /cell_line="E4181324 WSNO:9011"
FT                   /cell_type="homozygous typing cells WS 9011"
FT                   /tissue_type="cultured B-lymphocytes"
FT                   /db_xref="taxon:9606"
FT   regulatory      <1..141
FT                   /note="proximal promoter"
FT                   /regulatory_class="promoter"
FT   regulatory      15..29
FT                   /note="X box"
FT                   /regulatory_class="other"
FT   regulatory      49..58
FT                   /note="Y box"
FT                   /regulatory_class="other"
FT   regulatory      75..80
FT                   /regulatory_class="CAAT_signal"
FT   regulatory      112..117
FT                   /regulatory_class="TATA_box"
FT   exon            141..>291
FT                   /gene="HLA-DRB1"
FT                   /allele="HLA-DRB1*1502"
FT   mRNA            141..>291
FT                   /gene="HLA-DRB1"
FT                   /allele="HLA-DRB1*1502"
FT   CDS             204..>291
FT                   /gene="HLA-DRB1"
FT                   /allele="HLA-DRB1*1502"
FT                   /product="MHC class II antigen"
FT                   /note="HLA-DR beta 1"
FT                   /db_xref="UniProtKB/TrEMBL:Q06653"
FT                   /protein_id="CAA45844.1"
FT                   /translation="MVCLKLPGGSCMTALTVTLMVLSSPLALS"
XX
SQ   Sequence 291 BP; 60 A; 80 C; 73 G; 78 T; 0 other;
     catacagcat ctctgaccag caactgatga tgctattgaa ctcagatgct gattggttct        60
     ccaacacgag attacccaac ccaggagcaa ggaaatcagt aacttcctcc ctataacttg       120
     gaatgtgggt ggaggggttc atagttctcc ctgagtgaga cttgcctgct tctctggccc       180
     ctggtcctgt cctgttctcc agcatggtgt gtctgaagct ccctggaggc tcctgcatga       240
     cagcgctgac agtgacactg atggtgctga gctccccact ggctttgtct g                291
//