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EBI Dbfetch

ID   X64442; SV 1; linear; genomic DNA; STD; HUM; 291 BP.
XX
AC   X64442;
XX
DT   19-APR-1993 (Rel. 35, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 12)
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DE   Homo sapiens HLA-DRB gene 5'region, HLA-DRB*0802 allele
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KW   class II genes; class II major histocompatibility complex; HLA-DR Beta1;
KW   HLA-DRB genes; HLA-DRB1*0802 gene.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-291
RA   Eliaou J.;
RT   ;
RL   Submitted (13-FEB-1992) to the INSDC.
RL   J. Eliaou, University Hospital / INSERM U291, Lab d'Immunologie, Hopital
RL   Saint Eloi, 34059 Montpellier Cedex, FRANCE
XX
RN   [4]
RP   1-291
RX   DOI; 10.1007/BF00216386.
RX   PUBMED; 8462990.
RA   Louis P., Eliaou J.F., Kerlan-Candon S., Pinet V., Vincent R.D., Clot J.;
RT   "Polymorphism in the regulatory region of HLA-DRB genes correlating with
RT   haplotype evolution";
RL   Immunogenetics 38(1):21-26(1993).
XX
DR   MD5; dc6e81b76b0aeea178d9022806d6dc6a.
DR   Ensembl-Gn; ENSG00000206240; homo_sapiens.
DR   Ensembl-Gn; ENSG00000206306; homo_sapiens.
DR   Ensembl-Tr; ENST00000328980; homo_sapiens.
DR   Ensembl-Tr; ENST00000399450; homo_sapiens.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..291
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.3"
FT                   /isolate="homozygous typing cell work shop number 9071"
FT                   /mol_type="genomic DNA"
FT                   /cell_line="Olga"
FT                   /cell_type="homozygous typing cells WS 9071"
FT                   /tissue_type="cultured B-lymphocytes"
FT                   /germline
FT                   /db_xref="taxon:9606"
FT   promoter        1..141
FT                   /note="proximal promoter"
FT   misc_signal     15..29
FT                   /note="X box"
FT   misc_signal     49..58
FT                   /note="Y box"
FT   CAAT_signal     75..80
FT   TATA_signal     112..117
FT   misc_feature    141
FT                   /note="cap site"
FT   exon            <204..>291
FT                   /gene="HLA-DRB"
FT                   /allele="HLA-DRB*0802"
FT                   /number=1
FT   CDS             204..>291
FT                   /gene="HLA-DRB"
FT                   /allele="HLA-DRB*0802"
FT                   /product="MHC class II antigen"
FT                   /db_xref="UniProtKB/TrEMBL:A0N9A4"
FT                   /protein_id="CAL69444.1"
FT                   /translation="MVCLRLPGGSCMAVLTVTLMVLSSPLALA"
FT   sig_peptide     204..290
FT                   /gene="HLA-DRB"
FT                   /allele="HLA-DRB*0802"
FT   mat_peptide     291..>291
FT                   /gene="HLA-DRB"
FT                   /allele="HLA-DRB*0802"
FT                   /product="MHC class II antigen"
XX
SQ   Sequence 291 BP; 58 A; 78 C; 74 G; 81 T; 0 other;
     catacagcat ctctgaccag caactgatga tgctattgaa ctcagatgct gattcgttct        60
     ccaacactag tttacccaat ccaggagcaa ggaaatcagt aacttactcc ctataacttg       120
     gaatgtgggt ggaggggttc atagttctcc ctgagtgaga cttgcctgct gctctggccc       180
     ctggtcctgt cctgttctcc agcatggtgt gtctgaggct ccctggaggc tcctgcatgg       240
     cagttctgac agtgacactg atggtgctga gctccccact ggctttggct g                291
//


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