Dbfetch

Dbfetch

ID   M81179; SV 1; linear; genomic DNA; STD; HUM; 291 BP.
XX
AC   M81179;
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DT   12-MAR-1996 (Rel. 47, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 3)
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DE   Human (WS 9038) MHC class II HLA-DR-beta gene, promoter region.
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KW   cell surface glycoprotein; class II gene; integral membrane protein;
KW   major histocompatibility complex; promoter.
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OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
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RN   [1]
RP   1-291
RA   Louis P., Eliaou J.-F., Pinet V., Clot J.;
RT   "Allelic polymorphism in promoter region of HLA-DRB genes";
RL   Unpublished.
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DR   MD5; 372dca9010ad1371aa6f21e3c1837fae.
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FH   Key             Location/Qualifiers
FH
FT   source          1..291
FT                   /organism="Homo sapiens"
FT                   /isolate="WS 9038"
FT                   /mol_type="genomic DNA"
FT                   /cell_line="AMAI"
FT                   /cell_type="cultured B lymphocytes, homozygous typing
FT                   cells"
FT                   /db_xref="taxon:9606"
FT   gene            1..291
FT                   /gene="HLA-DRB"
FT   regulatory      1..141
FT                   /gene="HLA-DRB"
FT                   /note="proximal promoter"
FT                   /regulatory_class="promoter"
FT   regulatory      15..29
FT                   /gene="HLA-DRB"
FT                   /standard_name="X box"
FT                   /regulatory_class="other"
FT   regulatory      49..58
FT                   /gene="HLA-DRB"
FT                   /standard_name="Y box"
FT                   /regulatory_class="other"
FT   regulatory      75..80
FT                   /gene="HLA-DRB"
FT                   /note="CAAT box"
FT                   /regulatory_class="CAAT_signal"
FT   regulatory      112..117
FT                   /gene="HLA-DRB"
FT                   /note="TATA box"
FT                   /regulatory_class="TATA_box"
FT   misc_feature    141
FT                   /gene="HLA-DRB"
FT                   /note="cap site"
FT   exon            141..>291
FT                   /gene="HLA-DRB"
FT                   /number=1
FT   sig_peptide     204..290
FT                   /gene="HLA-DRB"
FT   CDS             204..>291
FT                   /codon_start=1
FT                   /gene="HLA-DRB"
FT                   /product="MHC HLA-DR-beta cell surface glycoprotein"
FT                   /db_xref="UniProtKB/TrEMBL:O19737"
FT                   /protein_id="AAA91846.1"
FT                   /translation="MVCLRLPGGSCMAVLTVTLMVLSSPLALA"
FT   mat_peptide     291..>291
FT                   /gene="HLA-DRB"
XX
SQ   Sequence 291 BP; 59 A; 78 C; 74 G; 80 T; 0 other;
     catacagcat ctctgaccag caactgatga tgctattgaa ctcagatgct gattcgttct        60
     ccaacactag attacccaat ccaggagcaa ggaaatcagt aacttactcc ctataacttg       120
     gaatgtgggt ggaggggttc atagttctcc ctgagtgaga cttgcctgct gctctggccc       180
     ctggtcctgt cctgttctcc agcatggtgt gtctgaggct ccctggaggc tcctgcatgg       240
     cagttctgac agtgacactg atggtgctga gctccccact ggctttggct g                291
//