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EBI Dbfetch

ID   L33415; SV 1; linear; mRNA; STD; MUS; 2972 BP.
XX
AC   L33415;
XX
DT   18-APR-1995 (Rel. 43, Created)
DT   04-MAR-2000 (Rel. 63, Last updated, Version 2)
XX
DE   Mouse integral membrane protein (Nramp2) mRNA, complete cds.
XX
KW   integral membrane protein.
XX
OS   Mus musculus (house mouse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea;
OC   Muridae; Murinae; Mus; Mus.
XX
RN   [1]
RP   1-2972
RX   DOI; 10.1016/0888-7543(95)80053-O.
RX   PUBMED; 7789986.
RA   Gruenheid S., Cellier M., Vidal S., Gros P.;
RT   "Identification and characterization of a second mouse Nramp gene";
RL   Genomics 25(2):514-525(1995).
XX
DR   MD5; 7576501d72fdd774eaabd3bb3a4b85da.
DR   Ensembl-Gn; ENSMUSG00000023030; mus_musculus.
DR   Ensembl-Tr; ENSMUST00000023774; mus_musculus.
DR   Ensembl-Tr; ENSMUST00000138843; mus_musculus.
DR   EuropePMC; PMC100035; 11598030.
DR   EuropePMC; PMC18345; 10781110.
DR   EuropePMC; PMC18702; 9448300.
DR   EuropePMC; PMC1895407; 16239432.
DR   EuropePMC; PMC2575913; 18755804.
DR   EuropePMC; PMC2791006; 19801673.
DR   EuropePMC; PMC99945; 11604510.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..2972
FT                   /organism="Mus musculus"
FT                   /mol_type="mRNA"
FT                   /cell_line="70/Z"
FT                   /cell_type="pre-B"
FT                   /tissue_lib="lambda gt11"
FT                   /note="vector lambda gt11"
FT                   /db_xref="taxon:10090"
FT   5'UTR           1..60
FT   mRNA            1..2972
FT   CDS             61..1767
FT                   /codon_start=1
FT                   /gene="Nramp2"
FT                   /product="integral membrane protein"
FT                   /function="potential transporter"
FT                   /note="transmembrane domains 1 through 12 (aa's): (71..90),
FT                   (98..117), (155..174), (180..199), (210..229), (255..274),
FT                   (300..319), (361..380), (412..429), (441..461), (478..499),
FT                   (507..527); N-glycosylation sites (aa 33..35, 336..338,
FT                   337..339, 349..351); binding-protein-dependent transport
FT                   system inner membrane component signature (aa 384..403)"
FT                   /db_xref="GOA:P49282"
FT                   /db_xref="InterPro:IPR001046"
FT                   /db_xref="MGI:MGI:1345279"
FT                   /db_xref="UniProtKB/Swiss-Prot:P49282"
FT                   /protein_id="AAC42051.1"
FT                   /translation="MVLDPKEKMPDDGASGDHGDSASLGAINPAYSNSSLPHSTGDSEE
FT                   PFTTYFDEKIPIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKL
FT                   LWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQ
FT                   EVIGSAIAINLLSAGRVPVWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTF
FT                   GYEYITVKPSQSQVLRGMFVPSCPGCRTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQV
FT                   NRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNKQVVEVCKNNSSP
FT                   HADLFPSDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVME
FT                   GFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPIL
FT                   TFTSLRPVMSEFSNGIGWRIAGGILVLIVCSINMYFVVVYVQELGHVALYVVAAVVSVA
FT                   YLTFVFYLGWQCLIALGLSFLDCGRSYRLGLTAQPELYLLNTVDADSVVSR"
FT   3'UTR           1768..2941
FT   polyA_site      2942..2972
XX
SQ   Sequence 2972 BP; 607 A; 743 C; 786 G; 836 T; 0 other;
     gtgtgtggag gtggcggagc cgaatcctat tctaagagca cagaccctca ggtatctacc        60
     atggtgttgg atcctaaaga aaagatgcca gacgatggcg cttctgggga ccatggagac       120
     tctgccagcc ttggcgccat caaccctgcc tacagcaact catccctccc acattccact       180
     ggagactctg aggagccctt caccacctac tttgatgaga aaatccccat tcctgaggag       240
     gagtactctt gttttagctt tcgtaaactc tgggcgttca cggggcctgg ctttcttatg       300
     agcattgcct acctagaccc aggaaacatc gaatctgatt tgcagtctgg agcagtggct       360
     ggatttaagc tgctctgggt gctcctcttg gccaccattg tggggctgct gctccagcgc       420
     cttgcagcga gacttggagt ggtcaccggc ttgcatcttg ctgaagtatg tcaccgtcag       480
     tatcccaagg tcccacggat catcctgtgg ctgatggtgg agttggcaat cattggttct       540
     gacatgcagg aagtcattgg ctcagccatc gccatcaatc tcctgtctgc aggaagggtc       600
     cctgtgtggg gcggagtcct catcaccatc gcagacactt ttgtgtttct ttttttggac       660
     aaatatggct tgcggaagct ggaagcgttt tttggctttc tcatcactat catggccctc       720
     acgtttggat atgagtacat tacagtgaag cccagccaga gccaagtact caggggcatg       780
     ttcgtgccgt cctgtccagg gtgccgcacc cctcaggtgg agcaggcggt gggcatcgtg       840
     ggagctgtga tcatgccgca caacatgtac ctgcattctg ccttagtcaa gtctagacag       900
     gtgaatcggg ccaataagca ggaagtgcgg gaagccaata agtacttctt catcgagtcc       960
     tgcatcgcgc tctttgtttc cttcatcatc aatgtctttg tcgtgtccgt ctttgctgaa      1020
     gcattttttg agaaaaccaa caagcaggtg gttgaagtct gcaaaaataa cagcagcccc      1080
     catgctgacc tctttcccag tgacaactct actctggctg tggacatcta caaagggggt      1140
     gttgtgcttg gatgttactt cgggcctgca gctctctaca tctgggcagt ggggatcctg      1200
     gctgccggtc agagctccac catgactgga acctattctg gccagtttgt catggaggga      1260
     ttcctgaacc taaaatggtc gcgctttgcc cgagtgatcc tgacccggtc tatcgccatc      1320
     atccccaccc tgctcgtcgc tgtcttccag gatgtggagc acctaacggg gatgaatgac      1380
     ttcctgaatg tcctgcagag cttacagctc ccctttgctc tcatacccat cctcacgttc      1440
     acaagcctgc ggccagtgat gagtgagttt tccaatggaa taggctggag gattgccggt      1500
     ggcatcctgg tcctgatcgt ctgctccatc aacatgtact ttgtagtggt ttatgtccag      1560
     gagctagggc atgtggcact ctatgtggtg gctgcagtgg ttagcgtggc ttatttgacc      1620
     tttgtgttct acttgggttg gcagtgtttg attgcattgg gtctgtcttt cctggactgt      1680
     ggacgctcgt accgcctggg actgaccgct cagcctgaac tctatcttct gaacaccgtg      1740
     gatgctgact cagtggtgtc cagatgacta acagcccagg agaccttaag aacactttct      1800
     ctaagccctt tcgggccaag tgcctgttag caaatccctt agttcggagg tgagcttgtt      1860
     caaaggtttt tgaacaaagg agaagttctc ctcacggact cagggtaaaa gctgacagtt      1920
     gcgtatgggt cagagaccct tcggaggcag tgggcctgtg gcagctgtgc agtccctcag      1980
     gcttgtgtct gcacttctgg ggtttaaagt gtatcgatat gtatttatgt gaacccaaac      2040
     gtgccagttt gggtaagatt ttaaggttat aaaacttgat agatttttac aaatgccttt      2100
     caggtgagtt aggtctttgt tctatttggg taacaaatga gaaagggacc tttctgacga      2160
     tgaacttccc caaaataact cttgaagcgc tgctttacca cagtgtgtgt gtgtgtgtgt      2220
     gtgtgtgtgt gtgtgcgcgc gcgcgtgcct gcctgcttct gcttgtgggg gccacgggtt      2280
     ggcatcaggt gtctccagtc tctaccacag tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg      2340
     tgtgtgtgtg tgtgtgtgtg tgcgtgcgcg agtgcctgcc tgcttctgct tgtgggggcc      2400
     acgggttggc atcaggtgtc tccagtctct ctctgaacat ggagttcagt gtgtgactga      2460
     gctagccagc cagtaagttc aaggatcctc ctggcctcgc gccccaacac tgtggtccca      2520
     gatcagctgc tacgcccaga ttttacacag tgctggggac ccaaactcag gtcttcctgg      2580
     acagcaggta ctttaccaac tttccccctt tgtctctaca tcaagtgtgt ctgtggctgt      2640
     tgttccgttg gtgtctgtcc acctgccctt tcttcccact ctacgcgctg acactccaca      2700
     cactgtcctc accctgtctc taagggccgc ccgtatgtgt accgctgagt gttcctgagg      2760
     aatttaagca ttttaaggtg tgtgttagca gaggtctgag gctcgcactc gatgggaaca      2820
     cagaccatca gtttcacttt aagcaccgac actccaaacg cgcgtgtgca ggtagtgaag      2880
     ctttttggtt tttgctttaa tcccaaccag aaataatcat ccttgttata ataaagttca      2940
     tgcttaatag ctaaaaaaaa aaaaaaaaaa aa                                    2972
//


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