Dbfetch
ID DQ235685; SV 1; linear; genomic DNA; STD; HUM; 324 BP. XX AC DQ235685; XX DT 09-NOV-2005 (Rel. 85, Created) DT 17-JUN-2008 (Rel. 96, Last updated, Version 4) XX DE Homo sapiens MHC class II antigen (HLA-DRB1) gene, HLA-DRB1*14XX allele, DE exon 2 and partial cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-324 RX DOI; 10.1111/j.1399-0039.2006.00669.x. RX PUBMED; 17026471. RA Chen Q., Zou H., Xu X.H., Luo M., Wang J., Zuo Y.Q., Chen Y.H., Chen X.H., RA Chen X.L., Yao Z.Q., Song N., Zeng J., Mi X.Y., Sun S.X., Wang J.X., RA Zhao T.M.; RT "Characterization of HLA-B*5516, -B*1313, -B*9512, and -DRB1*1457 alleles RT identified in a southwest Chinese population"; RL Tissue Antigens 68(4):339-343(2006). XX RN [2] RP 1-324 RA Chen Q., Zou H., Xu X.-H., Zuo Y.-Q., Luo M., Chen X.-H., Chen Y.-H., RA Song N., Chen X.-L., Yao Z.-Q., Mi X.-Y., Wang J.-X., Zhao T.-M.; RT "Identification of a novel HLA-DRB1 allele (DRB1*14XX) with a DRB1*04 RT sequence motif"; RL Unpublished. XX RN [3] RP 1-324 RA Chen Q., Zou H., Xu X.-H., Zuo Y.-Q., Luo M., Chen X.-H., Chen Y.-H., RA Song N., Chen X.-L., Yao Z.-Q., Mi X.-Y., Wang J.-X., Zhao T.-M.; RT ; RL Submitted (10-OCT-2005) to the INSDC. RL MCIGS, NIAID, National Institutes of Health, Bldg. 50, Room 5511, 50 South RL Drive, Bethesda, MD 20892, USA XX DR MD5; c55d5f42a0daf2f1cc3aa6c2d78ba381. XX FH Key Location/Qualifiers FH FT source 1..324 FT /organism="Homo sapiens" FT /chromosome="6" FT /map="6p21.3" FT /mol_type="genomic DNA" FT /clone="12973" FT /db_xref="taxon:9606" FT gene <1..>324 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*14XX" FT mRNA <16..>285 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*14XX" FT /product="MHC class II antigen" FT CDS <16..>285 FT /codon_start=3 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*14XX" FT /product="MHC class II antigen" FT /note="human leukocyte antigen DRB1; similar to DRB1*1416; FT contains the DR4-specific QVKH motif" FT /db_xref="GOA:Q9GIY3" FT /db_xref="HGNC:HGNC:4948" FT /db_xref="IMGT/HLA:DRB1*14:57" FT /db_xref="InterPro:IPR000353" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR014745" FT /db_xref="InterPro:IPR036179" FT /db_xref="UniProtKB/Swiss-Prot:Q9GIY3" FT /protein_id="ABB52004.1" FT /translation="RFLEQVKHECHFFNGTERVRFLDRYFHNQEEFVRFDSDVGEYRAV FT TELGRPAAEYWNSQKDILEDERAAVDTYCRHNYGVVESFTVQRR" FT exon 16..285 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*14XX" FT /number=2 FT variation 180 FT /gene="HLA-DRB1" FT /replace="c" FT /note="results in tyrosine to histidine substitution" XX SQ Sequence 324 BP; 63 A; 81 C; 121 G; 59 T; 0 other; ttcttgtccc cccagcacgt ttcttggagc aggttaaaca tgagtgtcat ttcttcaatg 60 ggacggagcg ggtgcggttc ctggacagat acttccataa ccaggaggag ttcgtgcgct 120 tcgacagcga cgtgggggag taccgggcgg tgacggagct ggggcggcct gctgcggagt 180 actggaacag ccagaaggac atcctggaag acgagcgggc cgcggtggac acctactgca 240 gacacaacta cggggttgtg gagagcttca cagtgcagcg gcgaggtgag cgcggcgcgg 300 ggcggggcct gagtccctgt gagc 324 //