ID DQ235685; SV 1; linear; genomic DNA; STD; HUM; 324 BP.
XX
AC DQ235685;
XX
DT 09-NOV-2005 (Rel. 85, Created)
DT 17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE Homo sapiens MHC class II antigen (HLA-DRB1) gene, HLA-DRB1*14XX allele,
DE exon 2 and partial cds.
XX
KW .
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
XX
RN [1]
RP 1-324
RX DOI; 10.1111/j.1399-0039.2006.00669.x.
RX PUBMED; 17026471.
RA Chen Q., Zou H., Xu X.H., Luo M., Wang J., Zuo Y.Q., Chen Y.H., Chen X.H.,
RA Chen X.L., Yao Z.Q., Song N., Zeng J., Mi X.Y., Sun S.X., Wang J.X.,
RA Zhao T.M.;
RT "Characterization of HLA-B*5516, -B*1313, -B*9512, and -DRB1*1457 alleles
RT identified in a southwest Chinese population";
RL Tissue Antigens 68(4):339-343(2006).
XX
RN [2]
RP 1-324
RA Chen Q., Zou H., Xu X.-H., Zuo Y.-Q., Luo M., Chen X.-H., Chen Y.-H.,
RA Song N., Chen X.-L., Yao Z.-Q., Mi X.-Y., Wang J.-X., Zhao T.-M.;
RT "Identification of a novel HLA-DRB1 allele (DRB1*14XX) with a DRB1*04
RT sequence motif";
RL Unpublished.
XX
RN [3]
RP 1-324
RA Chen Q., Zou H., Xu X.-H., Zuo Y.-Q., Luo M., Chen X.-H., Chen Y.-H.,
RA Song N., Chen X.-L., Yao Z.-Q., Mi X.-Y., Wang J.-X., Zhao T.-M.;
RT ;
RL Submitted (10-OCT-2005) to the INSDC.
RL MCIGS, NIAID, National Institutes of Health, Bldg. 50, Room 5511, 50 South
RL Drive, Bethesda, MD 20892, USA
XX
DR MD5; c55d5f42a0daf2f1cc3aa6c2d78ba381.
XX
FH Key Location/Qualifiers
FH
FT source 1..324
FT /organism="Homo sapiens"
FT /chromosome="6"
FT /map="6p21.3"
FT /mol_type="genomic DNA"
FT /clone="12973"
FT /db_xref="taxon:9606"
FT gene <1..>324
FT /gene="HLA-DRB1"
FT /allele="HLA-DRB1*14XX"
FT mRNA <16..>285
FT /gene="HLA-DRB1"
FT /allele="HLA-DRB1*14XX"
FT /product="MHC class II antigen"
FT CDS <16..>285
FT /codon_start=3
FT /gene="HLA-DRB1"
FT /allele="HLA-DRB1*14XX"
FT /product="MHC class II antigen"
FT /note="human leukocyte antigen DRB1; similar to DRB1*1416;
FT contains the DR4-specific QVKH motif"
FT /db_xref="GOA:Q9GIY3"
FT /db_xref="HGNC:HGNC:4948"
FT /db_xref="IMGT/HLA:DRB1*14:57"
FT /db_xref="InterPro:IPR000353"
FT /db_xref="InterPro:IPR003006"
FT /db_xref="InterPro:IPR003597"
FT /db_xref="InterPro:IPR007110"
FT /db_xref="InterPro:IPR011162"
FT /db_xref="InterPro:IPR013783"
FT /db_xref="InterPro:IPR014745"
FT /db_xref="InterPro:IPR036179"
FT /db_xref="UniProtKB/Swiss-Prot:Q9GIY3"
FT /protein_id="ABB52004.1"
FT /translation="RFLEQVKHECHFFNGTERVRFLDRYFHNQEEFVRFDSDVGEYRAV
FT TELGRPAAEYWNSQKDILEDERAAVDTYCRHNYGVVESFTVQRR"
FT exon 16..285
FT /gene="HLA-DRB1"
FT /allele="HLA-DRB1*14XX"
FT /number=2
FT variation 180
FT /gene="HLA-DRB1"
FT /replace="c"
FT /note="results in tyrosine to histidine substitution"
XX
SQ Sequence 324 BP; 63 A; 81 C; 121 G; 59 T; 0 other;
ttcttgtccc cccagcacgt ttcttggagc aggttaaaca tgagtgtcat ttcttcaatg 60
ggacggagcg ggtgcggttc ctggacagat acttccataa ccaggaggag ttcgtgcgct 120
tcgacagcga cgtgggggag taccgggcgg tgacggagct ggggcggcct gctgcggagt 180
actggaacag ccagaaggac atcctggaag acgagcgggc cgcggtggac acctactgca 240
gacacaacta cggggttgtg gagagcttca cagtgcagcg gcgaggtgag cgcggcgcgg 300
ggcggggcct gagtccctgt gagc 324
//
