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EBI Dbfetch

ID   D00659; SV 1; linear; mRNA; STD; MUS; 2394 BP.
XX
AC   D00659;
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DT   03-JUN-1992 (Rel. 32, Created)
DT   24-SEP-2008 (Rel. 97, Last updated, Version 9)
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DE   Mus musculus CYP mRNA for aromatase P450, complete cds.
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KW   .
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OS   Mus musculus (house mouse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea;
OC   Muridae; Murinae; Mus; Mus.
XX
RN   [1]
RP   1-2394
RX   DOI; 10.1016/0003-9861(91)90354-L.
RX   PUBMED; 1897929.
RA   Terashima M., Toda K., Kawamoto T., Kuribayashi I., Ogawa Y., Maeda T.,
RA   Shizuta Y.;
RT   "Isolation of a full-length cDNA encoding mouse aromatase P450";
RL   Arch. Biochem. Biophys. 285(2):231-237(1991).
XX
DR   MD5; 03a9e1c134da311dbf3a51849693c90c.
DR   Ensembl-Gn; ENSMUSG00000032274; mus_musculus.
DR   Ensembl-Tr; ENSMUST00000034811; mus_musculus.
DR   EuropePMC; PMC2579313; 17975728.
DR   EuropePMC; PMC30697; 11248122.
DR   EuropePMC; PMC3337629; 22545003.
DR   EuropePMC; PMC4024188; 24839456.
XX
CC   These data kindly submitted in computer readable form by:
CC   Masako Terashima
CC   Department of Medical Chemistry
CC   Kochi Medical School
CC   Kohasu, Oko-cho
CC   Nankoku-shi, Kochi 783
CC   Japan
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FH   Key             Location/Qualifiers
FH
FT   source          1..2394
FT                   /organism="Mus musculus"
FT                   /strain="BALB/c"
FT                   /mol_type="mRNA"
FT                   /clone="pES-M1"
FT                   /tissue_type="ovary"
FT                   /note="176 bp upstream of SacI site"
FT                   /db_xref="taxon:10090"
FT   CDS             47..1558
FT                   /codon_start=1
FT                   /gene="CYP"
FT                   /product="aromatase P450"
FT                   /EC_number="1.14.14.1"
FT                   /note="subfamily XIX polypeptide"
FT                   /db_xref="GOA:P28649"
FT                   /db_xref="InterPro:IPR001128"
FT                   /db_xref="InterPro:IPR002401"
FT                   /db_xref="InterPro:IPR017972"
FT                   /db_xref="MGI:MGI:88587"
FT                   /db_xref="UniProtKB/Swiss-Prot:P28649"
FT                   /protein_id="BAA00551.1"
FT                   /translation="MFLEMLNPMQYNVTIMVPETVTVSAMPLLLIMGLLLLIWNCESSS
FT                   SIPGPGYCLGIGPLISHGRFLWMGIGSACNYYNKMYGEFMRVWISGEETLIISKSSSMF
FT                   HVMKHSHYISRFGSKRGLQCIGMHENGIIFNNNPSLWRTIRPFFMKALTGPGLVRMVEV
FT                   CVESIKQHLDRLGEVTDTSGYVDVLTLMRHIMLDTSNMLFLGIPLDESAIVKKIQGYFN
FT                   AWQALLIKPNIFFKISWLYRKYERSVKDLKDEIAVLVEKKRHKVSTAEKLEDCMDFATD
FT                   LIFAERRGDLTKENVNQCILEMLIAAPDTMSVTLYFMLLLVAEYPEVEAAILKEIHTVV
FT                   GDRDIKIEDIQNLKVVENFINESMRYQPVVDLVMRRALEDDVIDGYPVKKGTNIILNIG
FT                   RMHRLEYFPKPNEFTLENFEKNVPYRYFQPFGFGPRGCAGKYIAMVMMKVVLVTLLRRF
FT                   QVKTLQKRCIENIPKKNDLSLHPNEDRHLVEIIFSPRNSDKYLQQ"
FT   misc_feature    107..184
FT                   /note="membrane-spanning domain"
FT   misc_feature    1340..1411
FT                   /note="heme-binding domain"
FT   polyA_site      2394
FT                   /note="26 a nucleotides"
XX
SQ   Sequence 2394 BP; 643 A; 495 C; 607 G; 649 T; 0 other;
     cgttgctgtc gttttttttt tttcttctga ggccaaatag cgcaagatgt tcttggaaat        60
     gctgaacccc atgcagtata atgtcaccat catggtcccg gaaactgtga ctgtcagtgc       120
     catgccactc ctgctgatca tgggcctcct tctcctgatt tggaattgtg agagctcgtc       180
     ttcaatacca ggtcctggct actgtctggg aattgggccc ctcatttccc atggcagatt       240
     cttgtggatg gggattggaa gtgcctgcaa ctactacaat aagatgtatg gagagttcat       300
     gagagtctgg atcagtggag aggagacact cattatcagc aagtcctcaa gcatgttcca       360
     tgtcatgaag cacagtcact acatctcccg attcggcagc aagcgtgggc tgcagtgcat       420
     cggcatgcat gagaacggca tcatatttaa caacaacccg agcctttgga gaacaattcg       480
     ccctttcttt atgaaagctc tgacgggccc tggtcttgtt cgaatggtgg aagtttgtgt       540
     ggagtccatc aagcagcatt tggaccggct gggcgaagtc accgacacct cgggctacgt       600
     ggatgtgttg accctcatga gacacatcat gctggacacc tctaacatgc tcttcctggg       660
     gatccccctg gacgaaagtg ctattgtgaa gaaaatccag ggttacttta acgcctggca       720
     agctctcctc atcaaaccaa acatcttctt taagatttct tggctctaca gaaagtatga       780
     acgatccgtc aaggacttga aagacgagat agctgttttg gtggaaaaga agagacacaa       840
     agtttccaca gctgagaaac tggaagactg tatggatttt gcaactgatt tgattttcgc       900
     tgagagacgt ggagacctga cgaaagagaa cgtgaatcag tgcatactgg agatgctgat       960
     tgcagcccct gacaccatgt cggtcactct gtacttcatg ttacttctcg tcgcagagta      1020
     tccagaggtc gaagcagcaa tcctgaagga gatccacact gttgtgggtg acagagacat      1080
     aaagatcgag gatatccaaa atttaaaagt ggtggaaaac ttcattaatg aaagcatgcg      1140
     gtaccagcct gttgtggact tggtcatgcg cagagctctg gaggatgacg taattgacgg      1200
     ctacccggtt aaaaagggaa ctaacatcat tctgaacatc ggaagaatgc acaggctcga      1260
     gtacttccct aagcccaatg aatttaccct tgaaaacttt gagaagaatg ttccctacag      1320
     gtactttcag ccttttggct ttgggccccg cggctgtgct gggaagtaca tcgccatggt      1380
     gatgatgaaa gttgtcttgg ttacactttt gagacgattc caggtgaaga cactgcaaaa      1440
     aaggtgtatt gaaaacatac cgaaaaagaa tgacctgtcc ttgcacccaa atgaggacag      1500
     gcaccttgtg gaaataattt tctctccaag gaattcagac aagtacctcc aacagtgaag      1560
     aggtgtggcc tatctactct ggggcattac ttatccgtaa ttacatggaa accatccatt      1620
     ttatcgagta ggtggcgtga acctcaccat gaacatttga tggtctgtag aattttatga      1680
     tcatagctcc tatggtttgt catcaagctg ggcatccatc cagggagcca ggatgcaaaa      1740
     gaaaggagtc tgtgttgggg accagtgaag aaactgaagc cttaaaggac caatcctaca      1800
     atatatacct tgggaaagac agaccatcag taaaacacgt ctggtctcct gctagagttc      1860
     tacagctgtt gtcagcacat cgaaatgact ctggcagaag tacttaagtt attagaaagg      1920
     ccaggtcaac atcccagcat gtgggccagg cataaatgaa caacagaact ttcatatgtg      1980
     tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg cgcgcgagtg cgcgcccaca      2040
     agcatgtgcc atgtacgtat gcaagtctgt gtgtgtactt gtgcatgcat gaatacatag      2100
     tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg gtagactctt tctacattaa      2160
     acccagttgc ttacggtgga tccacatgta aactgtttgg gggcaaaagt gaaatatagg      2220
     gtgtcgtttc ttactctcaa tttgtgctcc caggagtgta gttagactgt agtaggtata      2280
     gattcaggta aaacatgcct aagtagtatt agcctgagta aaatatagct aggactctat      2340
     gtgtggtgta gggggaaaaa tcacatggtg catttcaaat aaagaagtct tttt            2394
//


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