Dbfetch
ID BC058710; SV 1; linear; mRNA; STD; MUS; 4643 BP.
XX
AC BC058710;
XX
DT 27-SEP-2003 (Rel. 77, Created)
DT 21-OCT-2008 (Rel. 97, Last updated, Version 4)
XX
DE Mus musculus phospholipase C, beta 1, mRNA (cDNA clone MGC:76381
DE IMAGE:6842016), complete cds.
XX
KW MGC.
XX
OS Mus musculus (house mouse)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
XX
RN [1]
RP 1-4643
RX DOI; 10.1073/pnas.242603899.
RX PUBMED; 12477932.
RG Mammalian Gene Collection Program Team
RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D.,
RA Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F.,
RA Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H.,
RA Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K.,
RA Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F.,
RA Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S.,
RA Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J.,
RA Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J.,
RA Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M.,
RA Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G.,
RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C.,
RA Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I.,
RA Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.;
RT "Generation and initial analysis of more than 15,000 full-length human and
RT mouse cDNA sequences";
RL Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002).
XX
RN [2]
RC NIH-MGC Project URL: http://mgc.nci.nih.gov
RP 1-4643
RA Strausberg R.;
RT ;
RL Submitted (22-SEP-2003) to the INSDC.
RL National Institutes of Health, Mammalian Gene Collection (MGC), Cancer
RL Genomics Office, National Cancer Institute, 31 Center Drive, Room 11A03,
RL Bethesda, MD 20892-2590, USA
XX
DR MD5; c7e3d3dd97c4befeaf912838853f61e0.
DR Ensembl-Gn; ENSMUSG00000051177; mus_musculus.
DR Ensembl-Gn; MGP_129S1SvImJ_G0026554; mus_musculus_129s1svimj.
DR Ensembl-Gn; MGP_AJ_G0026518; mus_musculus_aj.
DR Ensembl-Gn; MGP_AKRJ_G0026492; mus_musculus_akrj.
DR Ensembl-Gn; MGP_BALBcJ_G0026530; mus_musculus_balbcj.
DR Ensembl-Gn; MGP_C3HHeJ_G0026273; mus_musculus_c3hhej.
DR Ensembl-Gn; MGP_C57BL6NJ_G0026975; mus_musculus_c57bl6nj.
DR Ensembl-Gn; MGP_CASTEiJ_G0025734; mus_musculus_casteij.
DR Ensembl-Gn; MGP_CBAJ_G0026253; mus_musculus_cbaj.
DR Ensembl-Gn; MGP_DBA2J_G0026387; mus_musculus_dba2j.
DR Ensembl-Gn; MGP_FVBNJ_G0026351; mus_musculus_fvbnj.
DR Ensembl-Gn; MGP_LPJ_G0026491; mus_musculus_lpj.
DR Ensembl-Gn; MGP_NODShiLtJ_G0026371; mus_musculus_nodshiltj.
DR Ensembl-Gn; MGP_NZOHlLtJ_G0027030; mus_musculus_nzohlltj.
DR Ensembl-Gn; MGP_PWKPhJ_G0025470; mus_musculus_pwkphj.
DR Ensembl-Gn; MGP_WSBEiJ_G0025808; mus_musculus_wsbeij.
DR Ensembl-Tr; ENSMUST00000070724; mus_musculus.
DR Ensembl-Tr; ENSMUST00000110116; mus_musculus.
DR Ensembl-Tr; ENSMUST00000131552; mus_musculus.
DR Ensembl-Tr; MGP_129S1SvImJ_T0057897; mus_musculus_129s1svimj.
DR Ensembl-Tr; MGP_AJ_T0057928; mus_musculus_aj.
DR Ensembl-Tr; MGP_AKRJ_T0057872; mus_musculus_akrj.
DR Ensembl-Tr; MGP_BALBcJ_T0057866; mus_musculus_balbcj.
DR Ensembl-Tr; MGP_C3HHeJ_T0057561; mus_musculus_c3hhej.
DR Ensembl-Tr; MGP_C57BL6NJ_T0058343; mus_musculus_c57bl6nj.
DR Ensembl-Tr; MGP_CASTEiJ_T0057809; mus_musculus_casteij.
DR Ensembl-Tr; MGP_CBAJ_T0057533; mus_musculus_cbaj.
DR Ensembl-Tr; MGP_DBA2J_T0057632; mus_musculus_dba2j.
DR Ensembl-Tr; MGP_FVBNJ_T0057607; mus_musculus_fvbnj.
DR Ensembl-Tr; MGP_LPJ_T0057755; mus_musculus_lpj.
DR Ensembl-Tr; MGP_NODShiLtJ_T0057575; mus_musculus_nodshiltj.
DR Ensembl-Tr; MGP_NZOHlLtJ_T0058507; mus_musculus_nzohlltj.
DR Ensembl-Tr; MGP_PWKPhJ_T0057389; mus_musculus_pwkphj.
DR Ensembl-Tr; MGP_WSBEiJ_T0056862; mus_musculus_wsbeij.
XX
CC Contact: MGC help desk
CC Email: cgapbs-r@mail.nih.gov
CC Tissue Procurement: Dr. James Lin, University of Iowa
CC cDNA Library Preparation: M. Bento Soares, University of Iowa
CC cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
CC DNA Sequencing by: University of Iowa, Dr. M. Bento Soares and Dr.
CC Thomas L. Casavant.
CC Web site: http://genome.uiowa.edu
CC Contact: bento-soares@uiowa.edu; tom-casavant@uiowa.edu
CC Bonaldo,M.F., Akabogu,I., Bair,T., Bair,J., Crouch,K., Davis,A.,
CC Fishler,K., Keppel,C., Kucaba,T., Lebeck,M., Melo,A., Schaefer,K.,
CC Scheetz,T., Smith,C., Snir,E., Tack,D., Trout,K., Walters,J.,
CC Casavant,T., Soares,M.B.
CC Clone distribution: MGC clone distribution information can be found
CC through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
CC Series: Plate: Row: Column: 0.
XX
FH Key Location/Qualifiers
FH
FT source 1..4643
FT /organism="Mus musculus"
FT /lab_host="DH10B"
FT /strain="C57BL/6"
FT /mol_type="mRNA"
FT /clone_lib="NIH_BMAP_GH0"
FT /clone="MGC:76381 IMAGE:6842016"
FT /tissue_type="Brain"
FT /note="Vector: pYX-ASC"
FT /db_xref="taxon:10090"
FT gene 1..4643
FT /gene="Plcb1"
FT /note="synonym: Plcb"
FT CDS 337..3987
FT /codon_start=1
FT /product="Plcb1 protein"
FT /db_xref="GOA:Q9Z1B3"
FT /db_xref="InterPro:IPR000008"
FT /db_xref="InterPro:IPR000909"
FT /db_xref="InterPro:IPR001192"
FT /db_xref="InterPro:IPR001711"
FT /db_xref="InterPro:IPR009535"
FT /db_xref="InterPro:IPR011992"
FT /db_xref="InterPro:IPR011993"
FT /db_xref="InterPro:IPR014815"
FT /db_xref="InterPro:IPR015359"
FT /db_xref="InterPro:IPR016280"
FT /db_xref="InterPro:IPR017946"
FT /db_xref="InterPro:IPR028400"
FT /db_xref="InterPro:IPR035892"
FT /db_xref="InterPro:IPR037862"
FT /db_xref="MGI:MGI:97613"
FT /db_xref="UniProtKB/Swiss-Prot:Q9Z1B3"
FT /protein_id="AAH58710.1"
FT /translation="MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRT
FT DPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGHLEQRMIT
FT VVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQV
FT TPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPR
FT PEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPN
FT SSLAKKGQMSVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQL
FT AGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECA
FT FKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDL
FT MYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDD
FT DDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGL
FT EQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQI
FT NMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVG
FT TYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEG
FT GKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSN
FT PIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETSSEAPSETRTTPAENGVNHTASLA
FT PKPPSQAPHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEM
FT KDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSA
FT IEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEE
FT CQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVV
FT QYIKRLEEAQSKRQEKLVEKHNEIRQQILDEKPKLQTELEQEYQDKFKRLPLEILEFVQ
FT EAMKGKISEDSNHGSAPPSLASDAAKVNLKSPSSEEIERENPGREFDTPL"
FT misc_feature 1285..1728
FT /note="PI-PLC-X; Region: Phosphatidylinositol-specific
FT phospholipase C, X domain. This associates with pfam00387
FT to form a single structural unit"
FT misc_feature 1951..2304
FT /note="PI-PLC-Y; Region: Phosphatidylinositol-specific
FT phospholipase C, Y domain. This associates with pfam00388
FT to form a single structural unit"
FT misc_feature 2365..2664
FT /note="C2; Region: Protein kinase C conserved region 2
FT (CalB)"
XX
SQ Sequence 4643 BP; 1373 A; 1094 C; 1169 G; 1007 T; 0 other;
ctgaatggtg cgcttccagg cggcggccga gcaggatcca gcggcgggcg actcgcactg 60
cccggctctg ctcctccgcg tctcccgagg ctctacagtc accgcgggct ccagatcctg 120
cgtcccgccc ggggcatggc aggctgctgt accctcgcgt gtcgtcccgc ttactaagcg 180
gcgcgggcca gaggtgcgga ggccaagagg ccggaggccg gcgggcagcg aagcccagag 240
cctggtgaat cgagagccaa gcccgctcgc gcccggagct ccgcgtcccg tctccactgc 300
gctcgcccgg gccgcccgga gccccgatga gcccagatgg ctggggctca gcccggagtg 360
cacgccttgc aactcaagcc cgtgtgcgtg tccgacagcc tcaagaaggg caccaaattc 420
gtcaagtggg atgatgactc cactattgtt actccaatta ttttgaggac tgatcctcag 480
ggatttttct tttactggac agaccagaat aaggagacgg agctgttaga tctcagcctt 540
gtcaaggatg ccaggtgtgg gaagcacgcc aaagctccca aggaccccaa gttgcgtgaa 600
cttctggatg ttgggaacat cggacacttg gaacagcgca tgataactgt ggtgtatgga 660
ccagacctgg tgaacatttc ccacttgaat cttgtggctt ttcaagagga agtagccaag 720
gaatggacaa atgaggtttt cagcttggca acaaacctgc tggctcagaa catgtccagg 780
gacgcatttc tggagaaagc atatactaag ctcaagctcc aggtcacccc agaaggccgc 840
attcctctta aaaacatcta tcgattgttc tcagcagacc ggaagcgcgt tgaaactgca 900
ctagaggctt gtagtcttcc atcttcgagg aatgactcca ttccccaaga ggacttcact 960
ccagatgtat acagagtttt cctgaacaat ctctgtcccc gacctgaaat tgataacatc 1020
ttttctgaat ttggtgccaa aagcaaaccg tacctgacgg ttgatcagat gatggatttt 1080
atcaacctta agcagagaga tccccggctc aatgaaatcc tttacccacc tctgaagcag 1140
gagcaggtcc aagtgttgat tgagaaatat gagcccaaca gcagcctcgc caagaaaggg 1200
cagatgtcag tggatggatt catgcgctac ctgagcggag aagaaaatgg agtcgtttca 1260
cctgagaaac tggatttgaa cgaagacatg tctcagcccc tgtctcacta tttcatcaat 1320
tcctcgcaca acacctacct cacagctggc cagttggctg ggaactcgtc tgtagagatg 1380
tatcgccagg tgcttctgtc tggatgtcgc tgtgtggagc tggactgctg gaagggaagg 1440
accgctgagg aagagcctgt cattacccat ggattcacca tgacaacaga aatatccttc 1500
aaggaagtca tagaagccat cgcagagtgt gcgttcaaga cgtctccttt ccccatcctc 1560
ctttcctttg agaaccacgt ggattccccg aagcaacaag ccaagatggc cgagtattgc 1620
cgattaatct ttggtgatgc cctcctgatg gaaccactgg aaaaataccc actggaatct 1680
ggggtacctc ttccaagccc tatggattta atgtataaaa tcttggtgaa aaacaagaag 1740
aagtcgcaca agtcgtcaga gggaagtggt aagaagaagc tttcagagca agcttccaac 1800
acctacagcg actcctccag tgtgttcgag ccttcgtctc caggagctgg ggaagcagat 1860
acggagagtg atgacgatga cgacgacgat gactgtaaaa agtcttccat ggatgagggg 1920
acagctggca gcgaagccat ggccacagaa gagatgtcta acctggtgaa ctatattcag 1980
cctgtcaagt ttgagtcctt tgaaatttca aaaaaaagaa ataaaagctt tgaaatgtct 2040
tccttcgtgg aaaccaaagg acttgaacaa cttacaaagt ctccggtgga atttgtagaa 2100
tacaacaaga tgcaacttag caggatatat cccaagggaa cacgtgtgga ttcatccaac 2160
tacatgcctc aactcttctg gaatgctggc tgtcagatgg tggcgctcaa cttccagaca 2220
gtggatctag ctatgcagat aaacatgggc atgtatgagt acaatgggaa gagcggctat 2280
aggctgaagc cagagttcat gaggaggccg gacaagcatt ttgatccatt tactgaagga 2340
atcgtagatg ggatagtggc caacactcta tctgttaaga ttatttcagg tcagttcctc 2400
tctgataaga aagttgggac ttatgtggaa gtggatatgt ttggcttgcc tgtggacaca 2460
aggaggaagg catttaaaac caagacatcc caaggaaatg ctgtaaaccc tgtctgggaa 2520
gaagaaccta ttgtattcaa aaaggtagtt ctaccttctc tggcctgttt gaggatagca 2580
gcatatgaag agggaggcaa atttattggc caccggatat tgcctgtgca ggctattcgg 2640
ccaggctatc actacatctg cctgcggaat gagaggaacc agcccctgac gctgccagct 2700
gtctttgtct acatagaagt caaagattat gtgccagaca cgtatgcaga tgtaatcgaa 2760
gctctatcaa acccaatccg atatgtcaat ctgatggaac agagagctaa gcagctggct 2820
gcgttgaccc tggaggatga agaggaagta aagaaggagg ctgaccctgg agaaacatct 2880
tccgaggctc caagcgaaac caggacaacg ccagcagaga atggggtgaa tcacaccgca 2940
tcccttgcac ccaagccgcc ttcccaggct ccacacagcc agcctgctcc agggtctgtg 3000
aaggcacctg ccaaaacaga agatctgatc cagagcgtgt taacagaagt agaggcgcaa 3060
accatcgaag agctcaagca acagaaatcg ttcgtgaaac ttcaaaagaa acactacaaa 3120
gaaatgaaag acctggtgaa gagacaccac aagaaaacca cggagctcat taaggagcac 3180
acgaccaagt acaacgagat tcagaatgac tacctgagaa ggagggcagc cttggagaag 3240
tccgccaaaa aggacagcaa gaagaaatct gaacccagca gccctgacca cggctcatca 3300
gccattgagc aagacctcgc tgccctggat gcagaaatga ctcagaagtt gatagacttg 3360
aaagacaagc aacaacagca gctgcttaat cttcggcaag agcagtatta cagcgagaag 3420
taccaaaagc gagaacacat taaactgctt attcagaagt tgacagatgt tgcagaagag 3480
tgtcagaaca atcagttaaa gaagctgaag gaaatctgcg agaaagagaa gaaggaatta 3540
aagaagaaaa tggataagaa gaggcaagag aagataacag aagccaagtc caaagacaaa 3600
agccagatgg aagaggagaa gacagagatg atccgatcgt acatccagga ggtggttcag 3660
tacatcaaga ggttagagga agcacaaagt aaaagacaag aaaaactcgt ggagaaacac 3720
aatgagatcc gccagcagat cctcgatgag aagcccaagc tgcagacgga gctggagcaa 3780
gaataccaag acaagttcaa aaggctgccc ctggagattc tggagtttgt acaggaagcc 3840
atgaaaggga agatcagcga ggacagcaat cacggctctg cccctccctc tctggcctca 3900
gatgctgcaa aggtgaacct caagtctccc tccagtgagg agatagaaag agagaaccca 3960
ggaagagagt ttgatactcc tctgtgatgc ccctgtcagg ccttccagac atgcacagct 4020
gcttgagctc cagtggactc taatgacaaa tatcactgcc tgggccatct tcctgagaaa 4080
tatcccttag cctgaaatcc acaccaaagg gagacttcca gaaggatccg tgtgaaggtc 4140
ccataccctg gttccatgtg tcatgtggaa actattgcca gtcttagaca gaagggtgca 4200
tgtatgcagg atttttcttt ttgtcccaat agtaaattaa gagcaggcag ctcccaggct 4260
ccatggaata tgtaatgaag gacaatgtct tcttggacga aaatgagagc tcctgtcttc 4320
atttgaagct ctggtgtaca gtatttcaaa gtaaaagaaa tagtttgaga agtgcgcagc 4380
tccatttaac actatggaac attccacttt gagcattgtt ttcctaactg ccccgcaatt 4440
ccatgttttc aagttaacgt gtatagtgaa ttgtgtcatc ctttgctttg caggcactgg 4500
tggcttgccg tttgctaatt tatttatcac agaggcatct gtatttgcta ttgacatggc 4560
tttattagat accatagtga ctcatataag ctggtttctt ttataaaata aaaaaaaatc 4620
acatgaaaaa aaaaaaaaaa aaa 4643
//
