Dbfetch
ID BC058710; SV 1; linear; mRNA; STD; MUS; 4643 BP. XX AC BC058710; XX DT 27-SEP-2003 (Rel. 77, Created) DT 21-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Mus musculus phospholipase C, beta 1, mRNA (cDNA clone MGC:76381 DE IMAGE:6842016), complete cds. XX KW MGC. XX OS Mus musculus (house mouse) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. XX RN [1] RP 1-4643 RX DOI; 10.1073/pnas.242603899. RX PUBMED; 12477932. RG Mammalian Gene Collection Program Team RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., RA Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., RA Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., RA Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K., RA Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F., RA Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S., RA Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J., RA Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J., RA Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M., RA Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C., RA Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I., RA Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human and RT mouse cDNA sequences"; RL Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002). XX RN [2] RC NIH-MGC Project URL: http://mgc.nci.nih.gov RP 1-4643 RA Strausberg R.; RT ; RL Submitted (22-SEP-2003) to the INSDC. RL National Institutes of Health, Mammalian Gene Collection (MGC), Cancer RL Genomics Office, National Cancer Institute, 31 Center Drive, Room 11A03, RL Bethesda, MD 20892-2590, USA XX DR MD5; c7e3d3dd97c4befeaf912838853f61e0. DR Ensembl-Gn; ENSMUSG00000051177; mus_musculus. DR Ensembl-Gn; MGP_129S1SvImJ_G0026554; mus_musculus_129s1svimj. DR Ensembl-Gn; MGP_AJ_G0026518; mus_musculus_aj. DR Ensembl-Gn; MGP_AKRJ_G0026492; mus_musculus_akrj. DR Ensembl-Gn; MGP_BALBcJ_G0026530; mus_musculus_balbcj. DR Ensembl-Gn; MGP_C3HHeJ_G0026273; mus_musculus_c3hhej. DR Ensembl-Gn; MGP_C57BL6NJ_G0026975; mus_musculus_c57bl6nj. DR Ensembl-Gn; MGP_CASTEiJ_G0025734; mus_musculus_casteij. DR Ensembl-Gn; MGP_CBAJ_G0026253; mus_musculus_cbaj. DR Ensembl-Gn; MGP_DBA2J_G0026387; mus_musculus_dba2j. DR Ensembl-Gn; MGP_FVBNJ_G0026351; mus_musculus_fvbnj. DR Ensembl-Gn; MGP_LPJ_G0026491; mus_musculus_lpj. DR Ensembl-Gn; MGP_NODShiLtJ_G0026371; mus_musculus_nodshiltj. DR Ensembl-Gn; MGP_NZOHlLtJ_G0027030; mus_musculus_nzohlltj. DR Ensembl-Gn; MGP_PWKPhJ_G0025470; mus_musculus_pwkphj. DR Ensembl-Gn; MGP_WSBEiJ_G0025808; mus_musculus_wsbeij. DR Ensembl-Tr; ENSMUST00000070724; mus_musculus. DR Ensembl-Tr; ENSMUST00000110116; mus_musculus. DR Ensembl-Tr; ENSMUST00000131552; mus_musculus. DR Ensembl-Tr; MGP_129S1SvImJ_T0057897; mus_musculus_129s1svimj. DR Ensembl-Tr; MGP_AJ_T0057928; mus_musculus_aj. DR Ensembl-Tr; MGP_AKRJ_T0057872; mus_musculus_akrj. DR Ensembl-Tr; MGP_BALBcJ_T0057866; mus_musculus_balbcj. DR Ensembl-Tr; MGP_C3HHeJ_T0057561; mus_musculus_c3hhej. DR Ensembl-Tr; MGP_C57BL6NJ_T0058343; mus_musculus_c57bl6nj. DR Ensembl-Tr; MGP_CASTEiJ_T0057809; mus_musculus_casteij. DR Ensembl-Tr; MGP_CBAJ_T0057533; mus_musculus_cbaj. DR Ensembl-Tr; MGP_DBA2J_T0057632; mus_musculus_dba2j. DR Ensembl-Tr; MGP_FVBNJ_T0057607; mus_musculus_fvbnj. DR Ensembl-Tr; MGP_LPJ_T0057755; mus_musculus_lpj. DR Ensembl-Tr; MGP_NODShiLtJ_T0057575; mus_musculus_nodshiltj. DR Ensembl-Tr; MGP_NZOHlLtJ_T0058507; mus_musculus_nzohlltj. DR Ensembl-Tr; MGP_PWKPhJ_T0057389; mus_musculus_pwkphj. DR Ensembl-Tr; MGP_WSBEiJ_T0056862; mus_musculus_wsbeij. XX CC Contact: MGC help desk CC Email: cgapbs-r@mail.nih.gov CC Tissue Procurement: Dr. James Lin, University of Iowa CC cDNA Library Preparation: M. Bento Soares, University of Iowa CC cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) CC DNA Sequencing by: University of Iowa, Dr. M. Bento Soares and Dr. CC Thomas L. Casavant. CC Web site: http://genome.uiowa.edu CC Contact: bento-soares@uiowa.edu; tom-casavant@uiowa.edu CC Bonaldo,M.F., Akabogu,I., Bair,T., Bair,J., Crouch,K., Davis,A., CC Fishler,K., Keppel,C., Kucaba,T., Lebeck,M., Melo,A., Schaefer,K., CC Scheetz,T., Smith,C., Snir,E., Tack,D., Trout,K., Walters,J., CC Casavant,T., Soares,M.B. CC Clone distribution: MGC clone distribution information can be found CC through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov CC Series: Plate: Row: Column: 0. XX FH Key Location/Qualifiers FH FT source 1..4643 FT /organism="Mus musculus" FT /lab_host="DH10B" FT /strain="C57BL/6" FT /mol_type="mRNA" FT /clone_lib="NIH_BMAP_GH0" FT /clone="MGC:76381 IMAGE:6842016" FT /tissue_type="Brain" FT /note="Vector: pYX-ASC" FT /db_xref="taxon:10090" FT gene 1..4643 FT /gene="Plcb1" FT /note="synonym: Plcb" FT CDS 337..3987 FT /codon_start=1 FT /product="Plcb1 protein" FT /db_xref="GOA:Q9Z1B3" FT /db_xref="InterPro:IPR000008" FT /db_xref="InterPro:IPR000909" FT /db_xref="InterPro:IPR001192" FT /db_xref="InterPro:IPR001711" FT /db_xref="InterPro:IPR009535" FT /db_xref="InterPro:IPR011992" FT /db_xref="InterPro:IPR014815" FT /db_xref="InterPro:IPR015359" FT /db_xref="InterPro:IPR016280" FT /db_xref="InterPro:IPR017946" FT /db_xref="InterPro:IPR028400" FT /db_xref="InterPro:IPR035892" FT /db_xref="InterPro:IPR037862" FT /db_xref="MGI:MGI:97613" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z1B3" FT /protein_id="AAH58710.1" FT /translation="MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRT FT DPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGHLEQRMIT FT VVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQV FT TPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPR FT PEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPN FT SSLAKKGQMSVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQL FT AGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECA FT FKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDL FT MYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDD FT DDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGL FT EQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQI FT NMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVG FT TYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEG FT GKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSN FT PIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETSSEAPSETRTTPAENGVNHTASLA FT PKPPSQAPHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEM FT KDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSA FT IEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEE FT CQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVV FT QYIKRLEEAQSKRQEKLVEKHNEIRQQILDEKPKLQTELEQEYQDKFKRLPLEILEFVQ FT EAMKGKISEDSNHGSAPPSLASDAAKVNLKSPSSEEIERENPGREFDTPL" FT misc_feature 1285..1728 FT /note="PI-PLC-X; Region: Phosphatidylinositol-specific FT phospholipase C, X domain. This associates with pfam00387 FT to form a single structural unit" FT misc_feature 1951..2304 FT /note="PI-PLC-Y; Region: Phosphatidylinositol-specific FT phospholipase C, Y domain. This associates with pfam00388 FT to form a single structural unit" FT misc_feature 2365..2664 FT /note="C2; Region: Protein kinase C conserved region 2 FT (CalB)" XX SQ Sequence 4643 BP; 1373 A; 1094 C; 1169 G; 1007 T; 0 other; ctgaatggtg cgcttccagg cggcggccga gcaggatcca gcggcgggcg actcgcactg 60 cccggctctg ctcctccgcg tctcccgagg ctctacagtc accgcgggct ccagatcctg 120 cgtcccgccc ggggcatggc aggctgctgt accctcgcgt gtcgtcccgc ttactaagcg 180 gcgcgggcca gaggtgcgga ggccaagagg ccggaggccg gcgggcagcg aagcccagag 240 cctggtgaat cgagagccaa gcccgctcgc gcccggagct ccgcgtcccg tctccactgc 300 gctcgcccgg gccgcccgga gccccgatga gcccagatgg ctggggctca gcccggagtg 360 cacgccttgc aactcaagcc cgtgtgcgtg tccgacagcc tcaagaaggg caccaaattc 420 gtcaagtggg atgatgactc cactattgtt actccaatta ttttgaggac tgatcctcag 480 ggatttttct tttactggac agaccagaat aaggagacgg agctgttaga tctcagcctt 540 gtcaaggatg ccaggtgtgg gaagcacgcc aaagctccca aggaccccaa gttgcgtgaa 600 cttctggatg ttgggaacat cggacacttg gaacagcgca tgataactgt ggtgtatgga 660 ccagacctgg tgaacatttc ccacttgaat cttgtggctt ttcaagagga agtagccaag 720 gaatggacaa atgaggtttt cagcttggca acaaacctgc tggctcagaa catgtccagg 780 gacgcatttc tggagaaagc atatactaag ctcaagctcc aggtcacccc agaaggccgc 840 attcctctta aaaacatcta tcgattgttc tcagcagacc ggaagcgcgt tgaaactgca 900 ctagaggctt gtagtcttcc atcttcgagg aatgactcca ttccccaaga ggacttcact 960 ccagatgtat acagagtttt cctgaacaat ctctgtcccc gacctgaaat tgataacatc 1020 ttttctgaat ttggtgccaa aagcaaaccg tacctgacgg ttgatcagat gatggatttt 1080 atcaacctta agcagagaga tccccggctc aatgaaatcc tttacccacc tctgaagcag 1140 gagcaggtcc aagtgttgat tgagaaatat gagcccaaca gcagcctcgc caagaaaggg 1200 cagatgtcag tggatggatt catgcgctac ctgagcggag aagaaaatgg agtcgtttca 1260 cctgagaaac tggatttgaa cgaagacatg tctcagcccc tgtctcacta tttcatcaat 1320 tcctcgcaca acacctacct cacagctggc cagttggctg ggaactcgtc tgtagagatg 1380 tatcgccagg tgcttctgtc tggatgtcgc tgtgtggagc tggactgctg gaagggaagg 1440 accgctgagg aagagcctgt cattacccat ggattcacca tgacaacaga aatatccttc 1500 aaggaagtca tagaagccat cgcagagtgt gcgttcaaga cgtctccttt ccccatcctc 1560 ctttcctttg agaaccacgt ggattccccg aagcaacaag ccaagatggc cgagtattgc 1620 cgattaatct ttggtgatgc cctcctgatg gaaccactgg aaaaataccc actggaatct 1680 ggggtacctc ttccaagccc tatggattta atgtataaaa tcttggtgaa aaacaagaag 1740 aagtcgcaca agtcgtcaga gggaagtggt aagaagaagc tttcagagca agcttccaac 1800 acctacagcg actcctccag tgtgttcgag ccttcgtctc caggagctgg ggaagcagat 1860 acggagagtg atgacgatga cgacgacgat gactgtaaaa agtcttccat ggatgagggg 1920 acagctggca gcgaagccat ggccacagaa gagatgtcta acctggtgaa ctatattcag 1980 cctgtcaagt ttgagtcctt tgaaatttca aaaaaaagaa ataaaagctt tgaaatgtct 2040 tccttcgtgg aaaccaaagg acttgaacaa cttacaaagt ctccggtgga atttgtagaa 2100 tacaacaaga tgcaacttag caggatatat cccaagggaa cacgtgtgga ttcatccaac 2160 tacatgcctc aactcttctg gaatgctggc tgtcagatgg tggcgctcaa cttccagaca 2220 gtggatctag ctatgcagat aaacatgggc atgtatgagt acaatgggaa gagcggctat 2280 aggctgaagc cagagttcat gaggaggccg gacaagcatt ttgatccatt tactgaagga 2340 atcgtagatg ggatagtggc caacactcta tctgttaaga ttatttcagg tcagttcctc 2400 tctgataaga aagttgggac ttatgtggaa gtggatatgt ttggcttgcc tgtggacaca 2460 aggaggaagg catttaaaac caagacatcc caaggaaatg ctgtaaaccc tgtctgggaa 2520 gaagaaccta ttgtattcaa aaaggtagtt ctaccttctc tggcctgttt gaggatagca 2580 gcatatgaag agggaggcaa atttattggc caccggatat tgcctgtgca ggctattcgg 2640 ccaggctatc actacatctg cctgcggaat gagaggaacc agcccctgac gctgccagct 2700 gtctttgtct acatagaagt caaagattat gtgccagaca cgtatgcaga tgtaatcgaa 2760 gctctatcaa acccaatccg atatgtcaat ctgatggaac agagagctaa gcagctggct 2820 gcgttgaccc tggaggatga agaggaagta aagaaggagg ctgaccctgg agaaacatct 2880 tccgaggctc caagcgaaac caggacaacg ccagcagaga atggggtgaa tcacaccgca 2940 tcccttgcac ccaagccgcc ttcccaggct ccacacagcc agcctgctcc agggtctgtg 3000 aaggcacctg ccaaaacaga agatctgatc cagagcgtgt taacagaagt agaggcgcaa 3060 accatcgaag agctcaagca acagaaatcg ttcgtgaaac ttcaaaagaa acactacaaa 3120 gaaatgaaag acctggtgaa gagacaccac aagaaaacca cggagctcat taaggagcac 3180 acgaccaagt acaacgagat tcagaatgac tacctgagaa ggagggcagc cttggagaag 3240 tccgccaaaa aggacagcaa gaagaaatct gaacccagca gccctgacca cggctcatca 3300 gccattgagc aagacctcgc tgccctggat gcagaaatga ctcagaagtt gatagacttg 3360 aaagacaagc aacaacagca gctgcttaat cttcggcaag agcagtatta cagcgagaag 3420 taccaaaagc gagaacacat taaactgctt attcagaagt tgacagatgt tgcagaagag 3480 tgtcagaaca atcagttaaa gaagctgaag gaaatctgcg agaaagagaa gaaggaatta 3540 aagaagaaaa tggataagaa gaggcaagag aagataacag aagccaagtc caaagacaaa 3600 agccagatgg aagaggagaa gacagagatg atccgatcgt acatccagga ggtggttcag 3660 tacatcaaga ggttagagga agcacaaagt aaaagacaag aaaaactcgt ggagaaacac 3720 aatgagatcc gccagcagat cctcgatgag aagcccaagc tgcagacgga gctggagcaa 3780 gaataccaag acaagttcaa aaggctgccc ctggagattc tggagtttgt acaggaagcc 3840 atgaaaggga agatcagcga ggacagcaat cacggctctg cccctccctc tctggcctca 3900 gatgctgcaa aggtgaacct caagtctccc tccagtgagg agatagaaag agagaaccca 3960 ggaagagagt ttgatactcc tctgtgatgc ccctgtcagg ccttccagac atgcacagct 4020 gcttgagctc cagtggactc taatgacaaa tatcactgcc tgggccatct tcctgagaaa 4080 tatcccttag cctgaaatcc acaccaaagg gagacttcca gaaggatccg tgtgaaggtc 4140 ccataccctg gttccatgtg tcatgtggaa actattgcca gtcttagaca gaagggtgca 4200 tgtatgcagg atttttcttt ttgtcccaat agtaaattaa gagcaggcag ctcccaggct 4260 ccatggaata tgtaatgaag gacaatgtct tcttggacga aaatgagagc tcctgtcttc 4320 atttgaagct ctggtgtaca gtatttcaaa gtaaaagaaa tagtttgaga agtgcgcagc 4380 tccatttaac actatggaac attccacttt gagcattgtt ttcctaactg ccccgcaatt 4440 ccatgttttc aagttaacgt gtatagtgaa ttgtgtcatc ctttgctttg caggcactgg 4500 tggcttgccg tttgctaatt tatttatcac agaggcatct gtatttgcta ttgacatggc 4560 tttattagat accatagtga ctcatataag ctggtttctt ttataaaata aaaaaaaatc 4620 acatgaaaaa aaaaaaaaaa aaa 4643 //