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EBI Dbfetch

ID   BC052977; SV 1; linear; mRNA; STD; HUM; 3692 BP.
XX
AC   BC052977;
XX
DT   06-JUN-2003 (Rel. 76, Created)
DT   15-OCT-2008 (Rel. 97, Last updated, Version 8)
XX
DE   Homo sapiens tumor necrosis factor receptor superfamily, member 1B, mRNA
DE   (cDNA clone MGC:60023 IMAGE:6198614), complete cds.
XX
KW   MGC.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-3692
RX   DOI; 10.1073/pnas.242603899.
RX   PUBMED; 12477932.
RG   Mammalian Gene Collection Program Team
RA   Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D.,
RA   Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F.,
RA   Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H.,
RA   Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K.,
RA   Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F.,
RA   Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S.,
RA   Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J.,
RA   Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J.,
RA   Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M.,
RA   Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G.,
RA   Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C.,
RA   Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I.,
RA   Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.;
RT   "Generation and initial analysis of more than 15,000 full-length human and
RT   mouse cDNA sequences";
RL   Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002).
XX
RN   [2]
RC   NIH-MGC Project URL: http://mgc.nci.nih.gov
RP   1-3692
RG   NIH MGC Project
RA   ;
RT   ;
RL   Submitted (02-JUN-2003) to the INSDC.
RL   National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda,
RL   MD 20892-2590, USA
XX
DR   MD5; c696f7c17485e5571a86eb33ccdea33c.
DR   Ensembl-Gn; ENSG00000028137; homo_sapiens.
DR   Ensembl-Tr; ENST00000376259; homo_sapiens.
DR   EuropePMC; PMC2118424; 17190839.
XX
CC   Contact: MGC help desk
CC   Email: cgapbs-r@mail.nih.gov
CC   Tissue Procurement: Dr. James R. Lupski
CC   cDNA Library Preparation: Life Technologies, Inc.
CC   cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
CC   DNA Sequencing by: Sequencing Group at the Stanford Human Genome
CC   Center, Stanford University School of Medicine, Stanford, CA  94305
CC   Web site:       http://www-shgc.stanford.edu
CC   Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
CC   Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
CC   R. M.
CC   Clone distribution: MGC clone distribution information can be found
CC   through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
CC   Series: IRAK Plate: 110 Row: n Column: 2
CC   This clone was selected for full length sequencing because it
CC   passed the following selection criteria: matched mRNA gi: 23312365.
CC   Differences found between this sequence and the human reference
CC   genome (build 36) are described in misc_difference features below
CC   and these differences were also compared to chimpanzee genomic
CC   sequences available as of 09/15/2004.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3692
FT                   /organism="Homo sapiens"
FT                   /lab_host="DH10B"
FT                   /mol_type="mRNA"
FT                   /clone_lib="Lupski_sympathetic_trunk"
FT                   /clone="MGC:60023 IMAGE:6198614"
FT                   /tissue_type="Peripheral Nervous System, sympathetic trunk"
FT                   /note="Vector: pCMV-SPORT6"
FT                   /db_xref="taxon:9606"
FT   gene            1..3692
FT                   /gene="TNFRSF1B"
FT                   /note="synonyms: p75TNFR, TNF-R75, p75, TBPII, CD120b,
FT                   TNF-R-II, TNFBR, TNFR80"
FT   CDS             88..1473
FT                   /codon_start=1
FT                   /gene="TNFRSF1B"
FT                   /product="tumor necrosis factor receptor superfamily,
FT                   member 1B"
FT                   /db_xref="GOA:P20333"
FT                   /db_xref="H-InvDB:HIT000053849.15"
FT                   /db_xref="HGNC:HGNC:11917"
FT                   /db_xref="InterPro:IPR001368"
FT                   /db_xref="InterPro:IPR020411"
FT                   /db_xref="PDB:1CA9"
FT                   /db_xref="PDB:3ALQ"
FT                   /db_xref="UniProtKB/Swiss-Prot:P20333"
FT                   /protein_id="AAH52977.1"
FT                   /translation="MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREY
FT                   YDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQ
FT                   VETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKP
FT                   CAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVST
FT                   RSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNC
FT                   VIMTQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDR
FT                   RAPTRNQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSS
FT                   QASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGM
FT                   KPS"
FT   misc_difference 1646
FT                   /gene="TNFRSF1B"
FT                   /note="'G' in cDNA is 'A' in the human genome. The
FT                   chimpanzee genome agrees with the human genomic sequence
FT                   and not the cDNA."
FT   misc_difference 1688
FT                   /gene="TNFRSF1B"
FT                   /note="'T' in cDNA is 'C' in the human genome."
FT   misc_difference 2378
FT                   /gene="TNFRSF1B"
FT                   /note="1 base in cDNA is not found in the human genome. The
FT                   chimpanzee genome agrees with the cDNA sequence, suggesting
FT                   that this difference is unlikely to be due to an artifact."
FT   misc_difference 2784..2785
FT                   /gene="TNFRSF1B"
FT                   /note="in the human genome : CC. The chimpanzee genome
FT                   agrees with the human genomic sequence and not the cDNA."
FT   misc_difference 3415
FT                   /gene="TNFRSF1B"
FT                   /note="1 base in cDNA is not found in the human genome. The
FT                   chimpanzee genome agrees with the cDNA sequence, suggesting
FT                   that this difference is unlikely to be due to an artifact."
FT   misc_difference 3676..3692
FT                   /gene="TNFRSF1B"
FT                   /note="polyA tail: 17 bases do not align to the human
FT                   genome."
XX
SQ   Sequence 3692 BP; 791 A; 1098 C; 1085 G; 718 T; 0 other;
     gagcgcagcg gagcctggag agaaggcgct gggctgcgag ggcgcgaggg cgcgagggca        60
     gggggcaacc ggaccccgcc cgcacccatg gcgcccgtcg ccgtctgggc cgcgctggcc       120
     gtcggactgg agctctgggc tgcggcgcac gccttgcccg cccaggtggc atttacaccc       180
     tacgccccgg agcccgggag cacatgccgg ctcagagaat actatgacca gacagctcag       240
     atgtgctgca gcaaatgctc gccgggccaa catgcaaaag tcttctgtac caagacctcg       300
     gacaccgtgt gtgactcctg tgaggacagc acatacaccc agctctggaa ctgggttccc       360
     gagtgcttga gctgtggctc ccgctgtagc tctgaccagg tggaaactca agcctgcact       420
     cgggaacaga accgcatctg cacctgcagg cccggctggt actgcgcgct gagcaagcag       480
     gaggggtgcc ggctgtgcgc gccgctgcgc aagtgccgcc cgggcttcgg cgtggccaga       540
     ccaggaactg aaacatcaga cgtggtgtgc aagccctgtg ccccggggac gttctccaac       600
     acgacttcat ccacggatat ttgcaggccc caccagatct gtaacgtggt ggccatccct       660
     gggaatgcaa gcatggatgc agtctgcacg tccacgtccc ccacccggag tatggcccca       720
     ggggcagtac acttacccca gccagtgtcc acacgatccc aacacacgca gccaactcca       780
     gaacccagca ctgctccaag cacctccttc ctgctcccaa tgggccccag ccccccagct       840
     gaagggagca ctggcgactt cgctcttcca gttggactga ttgtgggtgt gacagccttg       900
     ggtctactaa taataggagt ggtgaactgt gtcatcatga cccaggtgaa aaagaagccc       960
     ttgtgcctgc agagagaagc caaggtgcct cacttgcctg ccgataaggc ccggggtaca      1020
     cagggccccg agcagcagca cctgctgatc acagcgccga gctccagcag cagctccctg      1080
     gagagctcgg ccagtgcgtt ggacagaagg gcgcccactc ggaaccagcc acaggcacca      1140
     ggcgtggagg ccagtggggc cggggaggcc cgggccagca ccgggagctc agattcttcc      1200
     cctggtggcc atgggaccca ggtcaatgtc acctgcatcg tgaacgtctg tagcagctct      1260
     gaccacagct cacagtgctc ctcccaagcc agctccacaa tgggagacac agattccagc      1320
     ccctcggagt ccccgaagga cgagcaggtc cccttctcca aggaggaatg tgcctttcgg      1380
     tcacagctgg agacgccaga gaccctgctg gggagcaccg aagagaagcc cctgcccctt      1440
     ggagtgcctg atgctgggat gaagcccagt taaccaggcc ggtgtgggct gtgtcgtagc      1500
     caaggtgggc tgagccctgg caggatgacc ctgcgaaggg gccctggtcc ttccaggccc      1560
     ccaccactag gactctgagg ctctttctgg gccaagttcc tctagtgccc tccacagccg      1620
     cagcctccct ctgacctgca ggccaggagc agaggcagcg agttgtggaa agcctctgct      1680
     gccatggtgt gtccctctcg gaaggctggc tgggcatgga cgttcggggc atgctggggc      1740
     aagtccctga ctctctgtga cctgccccgc ccagctgcac ctgccagcct ggcttctgga      1800
     gcccttgggt tttttgtttg tttgtttgtt tgtttgtttg tttctccccc tgggctctgc      1860
     cccagctctg gcttccagaa aaccccagca tccttttctg cagaggggct ttctggagag      1920
     gagggatgct gcctgagtca cccatgaaga caggacagtg cttcagcctg aggctgagac      1980
     tgcgggatgg tcctggggct ctgtgcaggg aggaggtggc agccctgtag ggaacggggt      2040
     ccttcaagtt agctcaggag gcttggaaag catcacctca ggccaggtgc agtggctcac      2100
     gcctatgatc ccagcacttt gggaggctga ggcgggtgga tcacctgagg ttaggagttc      2160
     gagaccagcc tggccaacat ggtaaaaccc catctctact aaaaatacag aaattagccg      2220
     ggcgtggtgg cgggcaccta tagtcccagc tactcagaag cctgaggctg ggaaatcgtt      2280
     tgaacccggg aagcggaggt tgcagggagc cgagatcacg ccactgcact ccagcctggg      2340
     cgacagagcg agagtctgtc tcaaaagaaa aaaaaaaagc accgcctcca aatgccaact      2400
     tgtccttttg taccatggtg tgaaagtcag atgcccagag ggcccaggca ggccaccata      2460
     ttcagtgctg tggcctgggc aagataacgc acttctaact agaaatctgc caatttttta      2520
     aaaaagtaag taccactcag gccaacaagc caacgacaaa gccaaactct gccagccaca      2580
     tccaaccccc cacctgccat ttgcaccctc cgccttcact ccggtgtgcc tgcagccccg      2640
     cgcctccttc cttgctgtcc taggccacac catctccttt cagggaattt caggaactag      2700
     agatgactga gtcctcgtag ccatctctct actcctacct cagcctagac cctcctcctc      2760
     ccccagaggg gtgggttcct ctttaccact ccccaccttc aattcctggg ccccaaacgg      2820
     gctgccctgc cactttggta catggccagt gtgatcccaa gtgccagtct tgtgtctgcg      2880
     tctgtgttgc gtgtcgtggg tgtgtgtagc caaggtcggt aagttgaatg gcctgccttg      2940
     aagccactga agctgggatt cctccccatt agagtcagcc ttccccctcc cagggccagg      3000
     gccctgcaga ggggaaacca gtgtagcctt gcccggattc tgggaggaag caggttgagg      3060
     ggctcctgga aaggctcagt ctcaggagca tggggataaa ggagaaggca tgaaattgtc      3120
     tagcagagca ggggcagggt gataaattgt tgataaattc cactggactt gagcttggca      3180
     gctgaactat tggagggtgg gagagcccag ccattaccat ggagacaaga agggttttcc      3240
     accctggaat caagatgtca gactggctgg ctgcagtgac gtgcacctgt actcaggagg      3300
     ctgaggggag gatcactgga gcccaggagt ttgaggctgc agcgagctat gatcgcgcca      3360
     ctacactcca gcctgagcaa cagagtgaga ccctgtctct taaagaaaaa aaaaagtcag      3420
     actgctggga ctggccaggt ttctgcccac attggaccca catgaggaca tgatggagcg      3480
     cacctgcccc ctggtggaca gtcctgggag aacctcaggc ttccttggca tcacagggca      3540
     gagccgggaa gcgatgaatt tggagactct gtggggcctt ggttcccttg tgtgtgtgtg      3600
     ttgatcccaa gacaatgaaa gtttgcactg tatgctggac ggcattcctg cttatcaata      3660
     aacctgtttg ttttaaaaaa aaaaaaaaaa aa                                    3692
//


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