ID BC035203; SV 1; linear; mRNA; STD; MUS; 4933 BP.
XX
AC BC035203;
XX
DT 24-SEP-2002 (Rel. 73, Created)
DT 24-SEP-2008 (Rel. 97, Last updated, Version 12)
XX
DE Mus musculus phosphatidylinositol 3-kinase catalytic delta polypeptide,
DE mRNA (cDNA clone MGC:28528 IMAGE:4192906), complete cds.
XX
KW MGC.
XX
OS Mus musculus (house mouse)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
XX
RN [1]
RP 1-4933
RX DOI; 10.1073/pnas.242603899.
RX PUBMED; 12477932.
RG Mammalian Gene Collection Program Team
RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D.,
RA Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F.,
RA Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H.,
RA Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K.,
RA Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F.,
RA Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S.,
RA Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J.,
RA Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J.,
RA Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M.,
RA Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G.,
RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C.,
RA Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I.,
RA Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.;
RT "Generation and initial analysis of more than 15,000 full-length human and
RT mouse cDNA sequences";
RL Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002).
XX
RN [2]
RC NIH-MGC Project URL: http://mgc.nci.nih.gov
RP 1-4933
RG NIH MGC Project
RA ;
RT ;
RL Submitted (31-JUL-2002) to the INSDC.
RL National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda,
RL MD 20892-2590, USA
XX
DR MD5; 1cfc5e3a1fb51f571dc2bab82a0672c7.
DR Ensembl-Gn; ENSMUSG00000039936; mus_musculus.
DR Ensembl-Gn; MGP_129S1SvImJ_G0029144; mus_musculus_129s1svimj.
DR Ensembl-Gn; MGP_AJ_G0029109; mus_musculus_aj.
DR Ensembl-Gn; MGP_AKRJ_G0029057; mus_musculus_akrj.
DR Ensembl-Gn; MGP_BALBcJ_G0029125; mus_musculus_balbcj.
DR Ensembl-Gn; MGP_C3HHeJ_G0028846; mus_musculus_c3hhej.
DR Ensembl-Gn; MGP_C57BL6NJ_G0029574; mus_musculus_c57bl6nj.
DR Ensembl-Gn; MGP_CASTEiJ_G0028259; mus_musculus_casteij.
DR Ensembl-Gn; MGP_CBAJ_G0028808; mus_musculus_cbaj.
DR Ensembl-Gn; MGP_DBA2J_G0028957; mus_musculus_dba2j.
DR Ensembl-Gn; MGP_FVBNJ_G0028921; mus_musculus_fvbnj.
DR Ensembl-Gn; MGP_LPJ_G0029047; mus_musculus_lpj.
DR Ensembl-Gn; MGP_NODShiLtJ_G0028948; mus_musculus_nodshiltj.
DR Ensembl-Gn; MGP_NZOHlLtJ_G0029606; mus_musculus_nzohlltj.
DR Ensembl-Gn; MGP_PWKPhJ_G0027979; mus_musculus_pwkphj.
DR Ensembl-Gn; MGP_WSBEiJ_G0028339; mus_musculus_wsbeij.
DR Ensembl-Tr; ENSMUST00000038859; mus_musculus.
DR Ensembl-Tr; MGP_129S1SvImJ_T0069360; mus_musculus_129s1svimj.
DR Ensembl-Tr; MGP_AJ_T0069424; mus_musculus_aj.
DR Ensembl-Tr; MGP_AKRJ_T0069331; mus_musculus_akrj.
DR Ensembl-Tr; MGP_BALBcJ_T0069344; mus_musculus_balbcj.
DR Ensembl-Tr; MGP_C3HHeJ_T0069001; mus_musculus_c3hhej.
DR Ensembl-Tr; MGP_C57BL6NJ_T0069836; mus_musculus_c57bl6nj.
DR Ensembl-Tr; MGP_CASTEiJ_T0069481; mus_musculus_casteij.
DR Ensembl-Tr; MGP_CBAJ_T0068947; mus_musculus_cbaj.
DR Ensembl-Tr; MGP_DBA2J_T0069085; mus_musculus_dba2j.
DR Ensembl-Tr; MGP_FVBNJ_T0068986; mus_musculus_fvbnj.
DR Ensembl-Tr; MGP_LPJ_T0069160; mus_musculus_lpj.
DR Ensembl-Tr; MGP_NODShiLtJ_T0069005; mus_musculus_nodshiltj.
DR Ensembl-Tr; MGP_NZOHlLtJ_T0070022; mus_musculus_nzohlltj.
DR Ensembl-Tr; MGP_PWKPhJ_T0068963; mus_musculus_pwkphj.
DR Ensembl-Tr; MGP_WSBEiJ_T0068167; mus_musculus_wsbeij.
XX
CC Contact: MGC help desk
CC Email: cgapbs-r@mail.nih.gov
CC Tissue Procurement: Jeffrey E. Green, M.D.
CC cDNA Library Preparation: Life Technologies, Inc.
CC cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
CC DNA Sequencing by: Baylor College of Medicine Human Genome
CC Sequencing Center
CC Center code: BCM-HGSC
CC Web site: http://www.hgsc.bcm.tmc.edu/cdna/
CC Contact: amg@bcm.tmc.edu
CC Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
CC Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
CC A.N., Gibbs, R.A.
CC Clone distribution: MGC clone distribution information can be found
CC through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
CC Series: IRAK Plate: 37 Row: f Column: 12
CC This clone was selected for full length sequencing because it
CC passed the following selection criteria: matched mRNA gi: 6679318.
CC Differences found between this sequence and the mouse C57BL/6J
CC genome (build 36) are described in misc_difference features below.
XX
FH Key Location/Qualifiers
FH
FT source 1..4933
FT /organism="Mus musculus"
FT /lab_host="DH10B"
FT /strain="FVB/N"
FT /mol_type="mRNA"
FT /clone_lib="NCI_CGAP_SG2"
FT /clone="MGC:28528 IMAGE:4192906"
FT /tissue_type="Salivary gland, 10 week old female mouse"
FT /note="Vector: pCMV-SPORT6"
FT /db_xref="taxon:10090"
FT gene 1..4933
FT /gene="Pik3cd"
FT /note="synonym: p110delta"
FT misc_difference 126
FT /gene="Pik3cd"
FT /note="'G' in cDNA is 'C' in the mouse genome."
FT CDS 296..3433
FT /codon_start=1
FT /gene="Pik3cd"
FT /product="phosphatidylinositol 3-kinase catalytic delta
FT polypeptide"
FT /db_xref="GOA:Q8CI98"
FT /db_xref="InterPro:IPR000341"
FT /db_xref="InterPro:IPR000403"
FT /db_xref="InterPro:IPR001263"
FT /db_xref="InterPro:IPR002420"
FT /db_xref="InterPro:IPR003113"
FT /db_xref="InterPro:IPR008290"
FT /db_xref="InterPro:IPR011009"
FT /db_xref="InterPro:IPR015433"
FT /db_xref="InterPro:IPR016024"
FT /db_xref="InterPro:IPR018936"
FT /db_xref="InterPro:IPR029071"
FT /db_xref="InterPro:IPR035892"
FT /db_xref="InterPro:IPR036940"
FT /db_xref="InterPro:IPR037703"
FT /db_xref="MGI:MGI:1098211"
FT /db_xref="UniProtKB/TrEMBL:Q8CI98"
FT /protein_id="AAH35203.2"
FT /translation="MPPGVDCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTI
FT KQVLWHRAQYEPLFHMLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAR
FT EGDRVKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWL
FT QYSFPLQLEPSARGWRAGLLRVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALR
FT KKATVFRQPLVEQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSS
FT ILAMRDEQSNPAPQVQKPRAKPPPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMK
FT LVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVE
FT KAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGT
FT VRGNPNTESAAALVIYLPEVAPHPVYFPALEKILELGRHGERGRITEEEQLQLREILER
FT RGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPV
FT LSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLG
FT RALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKA
FT LNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCSVEQCTFM
FT DSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMT
FT PYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDR
FT AIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRER
FT VPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPE
FT LSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ"
FT misc_difference 598
FT /gene="Pik3cd"
FT /note="'G' in cDNA is 'C' in the mouse genome; no amino
FT acid change."
FT misc_difference 640
FT /gene="Pik3cd"
FT /note="'T' in cDNA is 'C' in the mouse genome; no amino
FT acid change."
FT misc_difference 1969
FT /gene="Pik3cd"
FT /note="'T' in cDNA is 'C' in the mouse genome; no amino
FT acid change."
FT misc_difference 2962
FT /gene="Pik3cd"
FT /note="'G' in cDNA is 'T' in the mouse genome; no amino
FT acid change."
FT misc_difference 3169
FT /gene="Pik3cd"
FT /note="'A' in cDNA is 'C' in the mouse genome; no amino
FT acid change."
FT misc_difference 3190
FT /gene="Pik3cd"
FT /note="'C' in cDNA is 'T' in the mouse genome; no amino
FT acid change."
FT misc_difference 3268
FT /gene="Pik3cd"
FT /note="'T' in cDNA is 'C' in the mouse genome; no amino
FT acid change."
FT misc_difference 3509
FT /gene="Pik3cd"
FT /note="'G' in cDNA is 'C' in the mouse genome."
FT misc_difference 3851
FT /gene="Pik3cd"
FT /note="'T' in cDNA is 'C' in the mouse genome."
FT misc_difference 4417
FT /gene="Pik3cd"
FT /note="'A' in cDNA is 'G' in the mouse genome."
FT misc_difference 4427
FT /gene="Pik3cd"
FT /note="'G' in cDNA is 'A' in the mouse genome."
FT misc_difference 4533
FT /gene="Pik3cd"
FT /note="'T' in cDNA is 'G' in the mouse genome."
FT misc_difference 4645
FT /gene="Pik3cd"
FT /note="'G' in cDNA is 'A' in the mouse genome."
FT misc_difference 4649
FT /gene="Pik3cd"
FT /note="'T' in cDNA is 'C' in the mouse genome."
FT misc_difference 4776..4784
FT /gene="Pik3cd"
FT /note="9 bases in cDNA are not found in the mouse genome."
FT misc_difference 4915..4933
FT /gene="Pik3cd"
FT /note="polyA tail: 19 bases do not align to the mouse
FT genome."
XX
SQ Sequence 4933 BP; 1110 A; 1405 C; 1398 G; 1020 T; 0 other;
cctgttatct gtagaaagga aacaaagtgg gaagtggagt gtgcggactg tcagtaggcg 60
ggctgtcccg ctgcgcgccc cgcctctggc tcactcgcgc ctagccttgg ggctgccagc 120
tccgcggacc cagctgctgg accgacatct aaggagctga gagccaggca gaagtgggat 180
gaagcccgct gatgccaaag tacctttaat ctcccaggca gaggggcctt ggctggtggt 240
ccttcttggc ccataccaaa caggaaaaca gacctcagag aagtaacaca acaggatgcc 300
ccctggggtg gactgcccca tggagttctg gaccaaagag gagagccaga gcgtggttgt 360
tgacttcttg ctgcccacag gggtctactt gaacttcccc gtgtcccgca atgccaacct 420
cagcaccatc aagcaggtgc tgtggcaccg tgcacagtat gagccactct tccacatgct 480
cagtgacccc gaggcctatg tgttcacctg tgtgaaccag acggcggagc agcaggagtt 540
ggaggatgag cagcggaggc tgtgcgacat ccagcccttc ctgcccgtgc tgcgcctggt 600
ggcccgagag ggggaccgcg tgaagaagct cattaactct cagatcagcc tcctcattgg 660
caaaggtctc catgagtttg attccctgcg ggacccggaa gtaaacgact tccgcactaa 720
gatgcgccag ttttgtgaag aggctgctgc tcaccgccag cagctgggct gggtggaatg 780
gctgcagtac agcttccccc tgcagctgga gccctcagca aggggttggc gggccggctt 840
attgcgtgtc agcaaccgag ccctgctggt caacgtgaag ttcgagggca gtgaggagag 900
cttcaccttc caggtatcca ccaaggacat gcccctggca ctgatggcct gtgccctccg 960
aaaaaaggcc acagtgttcc ggcagcctct ggtggagcag cctgaggaat atgccctgca 1020
ggtgaacggg aggcacgaat acctctacgg caactacccg ctctgccact ttcagtacat 1080
ctgcagctgc ctacacagcg ggctgacccc tcatctgacc atggtccact cctcctccat 1140
ccttgctatg cgggatgagc agagcaatcc tgccccccaa gtacagaaac cacgtgccaa 1200
acctcccccg atccctgcca agaagccctc ctctgtgtcc ctgtggtccc tggaacagcc 1260
attctccatt gagctgatcg agggccgaaa agtgaatgct gacgagcgga tgaagctggt 1320
tgttcaggcc gggctcttcc atggcaatga gatgctgtgc aagactgtgt caagctcgga 1380
ggtgaatgta tgctcagagc ccgtgtggaa gcagcgactg gagttcgata tcagcgtctg 1440
tgacctcccg cgcatggctc gactctgttt tgctctctat gccgtcgtgg agaaggctaa 1500
gaaggcacgc tccacaaaga agaagtctaa gaaggcggac tgccccatcg cttgggccaa 1560
cctcatgcta ttcgactaca aagatcagct caagacgggg gagcgctgcc tctacatgtg 1620
gccctctgtc ccagatgaga agggagagct gctgaatcct gcgggtacag tgcgcgggaa 1680
ccccaacacg gagagtgccg ctgccctggt catctacctg cctgaggtgg ccccccaccc 1740
tgtgtacttc cccgctctgg agaagatcct ggagctgggg cgtcacgggg agcgtgggcg 1800
catcacggag gaggagcagc tgcagctgcg ggagatcctg gaacggcggg gatccgggga 1860
actgtacgaa catgagaagg acctggtgtg gaagatgcgc cacgaagtcc aggagcattt 1920
cccagaggcg ctggcccgcc tgctgctggt caccaagtgg aataaacatg aggatgtggc 1980
ccagatgctc tatttgctgt gctcctggcc cgagctgcct gtgctgagcg ccctggaact 2040
tctggacttt agctttcccg actgctacgt gggctccttc gccatcaagt cccttcggaa 2100
gctgacggac gatgagctct tccagtacct tctgcagctg gtgcaagtgc tcaaatatga 2160
gtcctacctg gactgcgagc tgaccaaatt cttgctgggc cgagccctgg ctaaccgcaa 2220
gatcggacac ttcctgttct ggcacctccg ctctgagatg cacgtaccat cagtggctct 2280
gcggtttggt ctcatcatgg aagcctactg cagaggcagc acccaccaca tgaaggtgct 2340
gatgaagcag ggggaagcac tgagcaagct taaggcactg aatgactttg tgaaggtgag 2400
ttcccagaag accaccaagc cccaaaccaa ggagatgatg catatgtgca tgcgccagga 2460
gacctacatg gaggccctgt cccacctgca gtctccactc gaccccagca ccctgctgga 2520
ggaagtctgc agtgtggagc agtgcacctt catggactcc aaaatgaagc ccctgtggat 2580
catgtacagc agcgaggagg cgggcagtgc tggcaacgtg ggcatcatct ttaagaacgg 2640
ggatgacctc cgccaggaca tgctgactct gcagatgatc cagctcatgg acgtcctgtg 2700
gaagcaggag ggcctggacc tgaggatgac gccctacggc tgcctcccca ccggggaccg 2760
cacaggtctc atcgaggtgg tcctccactc ggacaccatc gccaacatcc agctgaacaa 2820
aagcaacatg gcggccacag ctgccttcaa caaggacgcc ctgctcaact ggctcaagtc 2880
caagaaccct ggggaggccc tggatcgggc cattgaggaa ttcaccctct cctgtgctgg 2940
ctactgtgtg gccacatatg tgctgggcat cggtgaccgg cacagcgaca acatcatgat 3000
cagagagagt gggcagctct tccacattga ttttggccac tttctgggga acttcaagac 3060
caagtttgga atcaaccgag agcgcgtccc cttcattctc acctacgact ttgtccacgt 3120
gatccagcag gggaagacta acaacagtga gaagtttgaa aggttccgag gctactgtga 3180
acgagcctac accatcctgc ggcgccacgg gctgcttttc ctccatctct tcgccctgat 3240
gcgggccgca ggtctgcctg agcttagttg ctccaaagat atccagtatc tcaaggactc 3300
tctggcactg gggaagacgg aggaagaggc gctaaagcac ttccgggtga agttcaacga 3360
agctctccga gaaagctgga aaaccaaagt caactggctg gcgcacaatg tgtccaagga 3420
taaccgacag taggaggcgc cccctggtgg tcatacggcg gttccctcct ggctttcagc 3480
cctagaggta aaaggacagt cctggagagc aggcatgtcc agtggtcacc aaagggaccc 3540
cagagcctga actgtccctc atggggaaga accacaccac tgcttcttgt ttacactggt 3600
aatttattta tgactcgaaa tgtttaagga acagaatagc cataaatgga agtgcatttc 3660
tgtgcagggg aggggtgatg tcctcatgat gtcatccccg gtcagcactg taacagcacc 3720
ttgaggatcg aacccctagt cttccaacct gtgggtcttg gcccagcaag gacagttctt 3780
ggggccttct tcccaggctc ccagcaggct gcctggaaca agcctggcgg tcacctggtg 3840
cctccatcct tagctcacct ccggccaccg ttgtgtggcc tacccaacca agcctccggc 3900
agctcttgag gaagccagga gcttccctct agactcaggc acacttgctc ggcactgctg 3960
aagcgacctc ttgggtttgg gtacgggaac gccctcacct ctcatttgcg ggtaagaaca 4020
cgatatgtag actctgtccc ttaccccgat ggctggggta agggacctgg cctccactac 4080
agttagtgta ttccaggcct tgaagcactc agaccggtgc cccatttagc tccgtgtggt 4140
cacgaatcaa gacgaagggc cagccagaat tgaagtcctc ttcgaagttc gtgtgagggg 4200
cacacaaggc agctttatgg acggacagga ctgatctctt ccagagctga aatcgcagaa 4260
ggcagctggg gagctaggct cgaaaagtgt gagcaaggac gagaacggaa ttcagtgtag 4320
tctgggcagt cagaggaact cgagaaacgc agtctcggcc tcctcccagg gatccaaacg 4380
ccagccaccc gcccggcttt tagagagccc agctcaaggg tcgcacgtgc ttatcgtccc 4440
accccaagca catctccatg tatcagctgc cacctcagga cctggatctc ccggtagcat 4500
tctgagactt tgagaaccat caccgctgtc tctccagcag cccagaacat ggctcaagga 4560
gccccttcat gttgatgagc ccagggtcca gcagtgagcg gtggtgcctc cgcagcaccc 4620
gctgaacccc tagtctgccc caccgacttt gaaataggaa acgtgtctgt gtgtgtgtat 4680
gtatgtatgc catgttattt attgaaaaga gtctaggtgc tctctggtgt ggctgcagat 4740
tctgcacagg ctcggccttt ctgggttggg tgtgtggcct gtgtacttgg ctggaagacg 4800
ggttttttgt taagtttttt cctctcattg atgggggctg agaccagttt gtgcaacctt 4860
gacacaacag gtaaagacag gtgaaaagaa ataaaaacgt ttttatgttc ttaaaaaaaa 4920
aaaaaaaaaa aaa 4933
//
