Dbfetch

ID   AF093245; SV 1; linear; genomic DNA; STD; MUS; 6320 BP.
XX
AC   AF093245;
XX
DT   11-MAY-1999 (Rel. 59, Created)
DT   15-APR-2005 (Rel. 83, Last updated, Version 3)
XX
DE   Mus musculus beta-defensin 3 (Bd3) gene, complete cds.
XX
KW   .
XX
OS   Mus musculus (house mouse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
XX
RN   [1]
RP   1-6320
RX   PUBMED; 10377137.
RA   Bals R., Wang X., Meegalla R.L., Wattler S., Weiner D.J., Nehls M.C.,
RA   Wilson J.M.;
RT   "Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in
RT   the epithelia of multiple organs";
RL   Infect Immun 67(7):3542-3547(1999).
XX
RN   [2]
RP   1-6320
RA   Bals R., Nehls M.C., Wattler S., Meegalla R., Wilson J.M.;
RT   ;
RL   Submitted (20-SEP-1998) to the INSDC.
RL   Institute for Human Gene Therapy, 3601 Spruce Street, Philadelphia, PA
RL   19104, USA
XX
DR   MD5; 280b9518aca9560405fafdce38a93e27.
DR   Ensembl-Gn; ENSMUSG00000039775; mus_musculus.
DR   Ensembl-Gn; MGP_129S1SvImJ_G0033419; mus_musculus_129s1svimj.
DR   Ensembl-Gn; MGP_AJ_G0033400; mus_musculus_aj.
DR   Ensembl-Gn; MGP_AKRJ_G0033330; mus_musculus_akrj.
DR   Ensembl-Gn; MGP_BALBcJ_G0033400; mus_musculus_balbcj.
DR   Ensembl-Gn; MGP_C3HHeJ_G0033112; mus_musculus_c3hhej.
DR   Ensembl-Gn; MGP_C57BL6NJ_G0033914; mus_musculus_c57bl6nj.
DR   Ensembl-Gn; MGP_CASTEiJ_G0032435; mus_musculus_casteij.
DR   Ensembl-Gn; MGP_CBAJ_G0033086; mus_musculus_cbaj.
DR   Ensembl-Gn; MGP_DBA2J_G0033240; mus_musculus_dba2j.
DR   Ensembl-Gn; MGP_FVBNJ_G0033188; mus_musculus_fvbnj.
DR   Ensembl-Gn; MGP_LPJ_G0033333; mus_musculus_lpj.
DR   Ensembl-Gn; MGP_NODShiLtJ_G0033225; mus_musculus_nodshiltj.
DR   Ensembl-Gn; MGP_NZOHlLtJ_G0033931; mus_musculus_nzohlltj.
DR   Ensembl-Gn; MGP_PWKPhJ_G0032148; mus_musculus_pwkphj.
DR   Ensembl-Gn; MGP_WSBEiJ_G0032552; mus_musculus_wsbeij.
DR   Ensembl-Tr; ENSMUST00000033852; mus_musculus.
DR   Ensembl-Tr; MGP_129S1SvImJ_T0088303; mus_musculus_129s1svimj.
DR   Ensembl-Tr; MGP_AJ_T0088389; mus_musculus_aj.
DR   Ensembl-Tr; MGP_AKRJ_T0088320; mus_musculus_akrj.
DR   Ensembl-Tr; MGP_BALBcJ_T0088338; mus_musculus_balbcj.
DR   Ensembl-Tr; MGP_C3HHeJ_T0087901; mus_musculus_c3hhej.
DR   Ensembl-Tr; MGP_C57BL6NJ_T0088854; mus_musculus_c57bl6nj.
DR   Ensembl-Tr; MGP_CASTEiJ_T0088431; mus_musculus_casteij.
DR   Ensembl-Tr; MGP_CBAJ_T0087848; mus_musculus_cbaj.
DR   Ensembl-Tr; MGP_DBA2J_T0088047; mus_musculus_dba2j.
DR   Ensembl-Tr; MGP_FVBNJ_T0087884; mus_musculus_fvbnj.
DR   Ensembl-Tr; MGP_LPJ_T0088076; mus_musculus_lpj.
DR   Ensembl-Tr; MGP_NODShiLtJ_T0087923; mus_musculus_nodshiltj.
DR   Ensembl-Tr; MGP_NZOHlLtJ_T0089144; mus_musculus_nzohlltj.
DR   Ensembl-Tr; MGP_PWKPhJ_T0087842; mus_musculus_pwkphj.
DR   Ensembl-Tr; MGP_WSBEiJ_T0086941; mus_musculus_wsbeij.
DR   EuropePMC; PMC116542; 10377137.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..6320
FT                   /organism="Mus musculus"
FT                   /chromosome="8"
FT                   /map="A4"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:10090"
FT   mRNA            join(<3412..3469,5141..>5274)
FT                   /gene="Bd3"
FT                   /product="beta-defensin 3"
FT   CDS             join(3412..3469,5141..5274)
FT                   /codon_start=1
FT                   /gene="Bd3"
FT                   /product="beta-defensin 3"
FT                   /note="antimicrobial peptide"
FT                   /db_xref="GOA:Q9WTL0"
FT                   /db_xref="InterPro:IPR001855"
FT                   /db_xref="MGI:MGI:1351612"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q9WTL0"
FT                   /protein_id="AAD29573.1"
FT                   /translation="MRIHYLLFAFLLVLLSPPAAFSKKINNPVSCLRKGGRCWNRCIGN
FT                   TRQIGSCGVPFLKCCKRK"
XX
SQ   Sequence 6320 BP; 1773 A; 1353 C; 1252 G; 1942 T; 0 other;
     agctgtgatg tcttccttag gcgacaggat cctcctgcat catttgctat ggaaaccttc        60
     acacacccct tgtgttaaac tacataacct gtgagttatt atctgcatta cctatgtcat       120
     ggactggata aaagatacaa actctgaccc atctctctct tcttgctttt tccctttttc       180
     aataaagacc tctcaaattg tgaactgtgc acgttggcat gatttattca ggaataaacc       240
     attttcaact aacaggggat gtacacatag cagtatacca caggagctgg ggaagccccc       300
     cccccacaac atacacactt ggcagggcgc cactggaact ggggggttca aaagtgcaat       360
     gtaccactcg agctgggggt atacacactt ggcagtgcac cactggagtt gaggggtgca       420
     cagagagcac tacaaccctg gaggtgtggg tgaacacata caaagcatag ctggggcctg       480
     gggaaacatg cacacacact cactcacact ctctctctca cacacatact cattcacata       540
     cacacacaca cacacacaca cacacacaca cacacacaca cacgcacaca cacatacaca       600
     cacacattca tacaccagtg taccaatgga cctatcccct gccttacctg gcttgactga       660
     gatcctaatt gtcctcaaga agacaagtga taaaattttg gtttgcctga gactcctctg       720
     gaagatggtg gaatattctg caagtaggcc tattagaagt gagctaggtt tggacaaggc       780
     acagcaatgg gtattggcag accagacccc tcccttctgc ttcctggtta ccagaaggtg       840
     aatgacttta cccaccacaa gctcatcgcc atttatgtcc tgccttcagt cagaccacaa       900
     agtagtggtg cccactgacc atggattgaa tctctaaggc ttgaaccaaa ataacttctc       960
     tttcatcaag gttgatttgt caaaagtatt tggccacaat gatagataat gaacacattt      1020
     gctttttact gtggaaagtg aggaaattat gcaaatggag aggggtggtg tattaattca      1080
     tgctgagtat ttacagacaa ttattccaca ttaagttttg tctgctcttc ctctgcctgg      1140
     aaaaatatct tagtgttggg atgagtaagc atgatttttc aatagacatc tgaatcacac      1200
     agggaagcaa agtcccaaag aggcatgaga ctgtatgtgg aaatcctcta atctcagaca      1260
     gaacttgttt ataacatgcc actgtatcct aacctagccc tgtcattccc taatccagca      1320
     gaaacttcct cattggatca agccattatt acagatcaac caccagctaa ttttaagaaa      1380
     ccctcaaaat gtagagcagg caaatgatga ccagagaaag gtataggtaa ggagaataga      1440
     gggatgtttg tgttttaaaa aacacaggag aattatgtct ggtttctact ggtctattgt      1500
     atgttagtat tactgaagct aatgagaggg gattggaact actcttagta gagtaaaatt      1560
     atgcaatttg aagtgatgga tatggtaact aacctgagtt gatcattccc taccctatct      1620
     atgtactgag atagtacaca gaaacccaca aatatgtaca tttactgtat cttgttttaa      1680
     tttaaaactt cttctttatg ccagtttatg ggattttcag agggaaaact aggaaagggg      1740
     ataacatttg aaatgtaaat aaagaaagta tctaataaaa aatatttgtc caccaattca      1800
     aaaaaggtgg cttttcacag cacatcagtg ggagtggggc attctagtgt gggtccaaac      1860
     tcttcattct tcagcctcaa atctgtttgc tgagaactcc atacaagagc ctttgtcaaa      1920
     gctgttcata cattattgat ttctgctcat atggttatta caacttcctg taaggaagaa      1980
     ggaatcctga gtaagataaa ttattttctc ttacaaaatc cttatttctc agttctcaga      2040
     atgagttaag ccatgataca tgtcaatggt tttctaggat aaagatgtaa agcttggtta      2100
     cagaatttcc aagagtcttc actcagagat gagccacaca gcacccctca gacagttcac      2160
     agcaagtgca gtagggagat ggttcaagag acttgaatct cactgtcatg gattgttttt      2220
     tttttttttt ttggttttct tccttttatt attaatatat tatttgctct ttgtaattct      2280
     catatatgac ttatcttgat catatcaaac atacccatat ctcctcttcc agtttccctg      2340
     tgttcctaaa ttcacgtgat gttctttatt tttaaataaa atcttgctta attaatttta      2400
     ctttaattga atccctgata atttgatcca ttttattgat gagtttatct ttttttatta      2460
     tatatttttt attacgtatt ttcctcaatt acatttccaa tgctatccaa aaagtccccc      2520
     ataccctccc cccccccact accctaccca cccattccca ctttttggcc ctggctttcc      2580
     cctgtactgg ggcatataaa gtttgcgtgt ccaatgggcc actgtcatgg attctaagga      2640
     tagaattcaa gaatcaactt gacccctcac cactgatact cacatcatct tagaaagaga      2700
     agaaccacag acccaaaggc tagtatgtcc cacaaagttc attacaaagt ggttagaacc      2760
     agctactccc tgctttcttc taggtgggaa tggggcacca tgttcaggta tcacattacc      2820
     aactcattgc attctctgag acaggaagca gcacacccat ctgactccac tgtagtaaat      2880
     gaactccact gttgagcagt aacttgggga aatctatgaa atgaggccca tgttctgacc      2940
     taaaaagctt ggagaacctt gacttggctc acattctgtt gcctccagca gctgagtgtg      3000
     cctaagctca aatggattta tgtgaaatta ctccccactg aggcctaagc ctgttgacag      3060
     actctaagat gaccaagtca aatgtctgag ttatagacaa gtaagctcca attgtaacca      3120
     gtaagaatgt cccaggacag cctgggtcca gctaagatgt aaggcaggaa gctgttcttg      3180
     ttgagcagtg caggaggaaa tcatctgggg atcctcacat ttgcataagg aacactgagt      3240
     gtgctctcaa agggtcactc cttgacaaga gaggtaaggt gctcttgttt cataattgta      3300
     attttgacgt tctattcagt gtcgaaatct acccaggagg cagcacctgg cactatataa      3360
     ggcactgagc tcaagtccct ctgcatctct gcccctcacc aggcttcagt catgaggatc      3420
     cattaccttc tctttgcatt tctcctggtg ctgctgtctc cacctgcagg tgagtcaggg      3480
     gagtagggtc atcccacact gatatgagag acaacaccct acatcaggtg tgtgtgtgtg      3540
     tgtgtgtgtg tgtgtgtgtg tgtgcgccta tgtatctctg tgtttgtctc ggagtctccc      3600
     tctctatgta tctttctgtt tctctgtgtt tgcatctctc tctgtgtctt tgtgtttctg      3660
     tgtctctatg tttgtgtctg tctgtctgtc tgtctatctc tctctctttc tgtgtgtgtg      3720
     catgtgtata cctttatgtc ccttaatctt cgtgtgttgg tttgtttccc tctcattgta      3780
     tgtgtgtgtg ttcctctgcg catgcatctg tctttctgtc tctatgtgta tatgtctgtc      3840
     tttctgtgta taagtccata tctatgtttc tgtctgtgtc tttttctcct ttttacatat      3900
     accctcctta cttttgcatt tttctttctt tcttctaagc attttaaaaa atgtgtattg      3960
     ttgactacta acacaaacca aggactcttt ctttttccct tgaaggagcc taaggtagac      4020
     aatgctcctc tcatctgcag caattgactt ccatttccta actcctgatg ctaagcttaa      4080
     gattatcaaa tgagtgtctt ataggtagct taaaaataat aacatgaaga atgtttgatt      4140
     cttacatgaa cagaaaggta ttaatttaga aatctttaca tataaggagt agagtctctg      4200
     cttactctag agaactcctc agaataacca gccttgcctg tgtttgagaa ctttctgctc      4260
     cccttagccc catggaatac ccctgagcac acagtgtcta cagggttaat gaggttcata      4320
     gcacagggga ggctattaaa tcctgtctcc caaacttttg cttaagtgta tttagtggaa      4380
     aagatttatt ttctgtaaat tatgtgtata tgtattgatt tgtgtatggc gatatgccaa      4440
     gtagtacagt acccaaagtg gttagaaaag ggcatctaat ctctcagaga tgcggttgtt      4500
     tgcaggtaca tatgggctgc ctgatatggt actaggaact tatctcaggt gttctgcagg      4560
     agctgtatgc actcctacag gctgagccat ctttccaggc tccaagctgt gtttcatact      4620
     tgcctttaga caaacagaat aatggggtta gacaactcat gtgagggagc taaaacaagc      4680
     aatgagttgg agaggaattg atgaacacat cttaggccaa cctgtggcct ctatatgtgt      4740
     gtgcacacat gcacattcat gtgcacagtc acactcagtg tctgtttcac atgctagaag      4800
     taggggcttg tgtatggaga agcaaaggca gggctgctaa gaagtagcta gggagtcaca      4860
     caaaatcttt cctgagctac tgcatgctgg ctttgaatac tccaatcagt caggggttga      4920
     gcagatcctt caacatttgg gtcctaggaa taccagcacc tcctctacac tgcaactgtg      4980
     cctgtctcga acaagaattg gattcagccc tgctaaaaca gacattactg tttgggcaga      5040
     acaatctgct gggatctact tatcataaga acacattggt atgtatttct gacctaccac      5100
     tttcaatttt aatgtatggt ttttcttact tatctttcag cttttagcaa aaaaatcaac      5160
     aatccagtaa gttgtttgag gaaaggaggc agatgctgga atcggtgcat tggcaacact      5220
     cgtcagattg gcagttgtgg agttcctttc ctcaaatgct gcaagagaaa atagagaaga      5280
     ccaagatccc gttaaacaaa gaaaacacca gaatttgctc ctccatgaag atggacaaat      5340
     cttaaaccaa attaatattc cttgattaaa tgcaaacaag tgctccctag cagctgtgtg      5400
     agcccacagt ttgttttctc atgggctgaa ttctaaaata cgtgtagatg tcaatcagtg      5460
     acacaagcag ggctctctta tgtttctgga ctttatggat atctgttcca gtctctgata      5520
     tgctaactga tttcctgtag acagcacaca cagccatcct acctgccttc ttcatccctt      5580
     tgcctcctta acctctgctt catccatcca atctgaaaga aaggcaaaga tggagactcc      5640
     agctactctt tagcttgtgc ctcttagtca tttatgcctt gtgtgtttgt ggctaagact      5700
     ttaatatact ctttggctat gaaagctctt gagtgtgggt tccagagtct cttgttcatt      5760
     tatgtactga ccaatgatgg gatatatcgc atcatgctat tttaaattga atggccaagt      5820
     tgagtcagtg ggaggctttg ttacatgtag atataagaca aaaggacctt atggacaaaa      5880
     aggccttatt aaaagcaata agaaagaaga gcagggttaa gaaaaaaaag gttatggtta      5940
     gtaaagcaaa agttcagagt ctgtcctagt cctgaccttc ccactggggc ttttacagta      6000
     tgatggtctc cccatctggc ttggacgggg cttttcagtt aatgtgcata caatttatat      6060
     tcatgagaat aattcaactc cagcacaata ctttagattt tcagaattct ctatctgaaa      6120
     gaagaaatga aactccagag aaaagataac tcacctggat agacacaact gataaaaaga      6180
     gtttttgtca aatggttgac atgtaataaa agaatgttgg ctgaagatac ataccataat      6240
     acagtatatc tttaaattta aagtcggagt ctgaagccag ggcactgtcc ataagtgtgt      6300
     gctgtgcaag cttacagatc                                                  6320
//