Dbfetch

ID   AB043785; SV 1; linear; genomic DNA; STD; MUS; 20993 BP.
XX
AC   AB043785;
XX
DT   17-OCT-2000 (Rel. 65, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 2)
XX
DE   Mus musculus AT3 gene for antithrombin, complete cds.
XX
KW   .
XX
OS   Mus musculus (house mouse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
XX
RN   [1]
RP   1-20993
RA   Kojima T.;
RT   ;
RL   Submitted (24-MAY-2000) to the INSDC.
RL   Tetsuhito Kojima, Nagoya University School of Health Sciencies, Department
RL   of Medical Technology; 1-1-20 Daiko-Minami, Higashi-ku, Nagoya, Aichi
RL   461-8673, Japan (E-mail:kojima@met.nagoya-u.ac.jp, Tel:81-52-719-3153,
RL   Fax:81-52-719-3153)
XX
RN   [2]
RX   DOI; 10.1172/JCI10489.
RX   PUBMED; 11018075.
RA   Ishiguro K., Kojima T., Kadomatsu K., Nakayama Y., Takagi A., Suzuki M.,
RA   Takeda N., Ito M., Yamamoto K., Matsushita T., Kusugami K., Muramatsu T.,
RA   Saito H.;
RT   "Complete antithrombin deficiency in mice results in embryonic lethality";
RL   J. Clin. Invest. 106(7):873-878(2000).
XX
DR   MD5; fa77f5f715f3f4fe9e99c770559cfe38.
DR   Ensembl-Gn; ENSMUSG00000026715; mus_musculus.
DR   Ensembl-Tr; ENSMUST00000064725; mus_musculus.
DR   EuropePMC; PMC517819; 11018075.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..20993
FT                   /organism="Mus musculus"
FT                   /strain="129/SVJ"
FT                   /mol_type="genomic DNA"
FT                   /sex="male"
FT                   /tissue_type="spleen"
FT                   /db_xref="taxon:10090"
FT   CDS             join(2901..2941,4740..5109,8836..9051,10761..10898,
FT                   12828..13218,15537..15601,17856..18032)
FT                   /codon_start=1
FT                   /transl_table=1
FT                   /gene="AT3"
FT                   /product="antithrombin"
FT                   /db_xref="GOA:Q543J5"
FT                   /db_xref="InterPro:IPR000215"
FT                   /db_xref="InterPro:IPR015555"
FT                   /db_xref="InterPro:IPR023795"
FT                   /db_xref="InterPro:IPR023796"
FT                   /db_xref="InterPro:IPR033829"
FT                   /db_xref="MGI:MGI:88095"
FT                   /db_xref="UniProtKB/TrEMBL:Q543J5"
FT                   /protein_id="BAB16827.1"
FT                   /translation="MYSPGAGSGAAGERKLCLLSLLLIGALGCAICHGNPVDDICIAKP
FT                   RDIPVNPLCIYRSPGKKATEEDGSEQKVPEATNRRVWELSKANSRFATNFYQHLADSKN
FT                   DNDNIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDTISEKTSDQIHFFFAKLNCRL
FT                   YRKANKSSDLVSANRLFGDKSLTFNESYQDVSEVVYGAKLQPLDFKENPEQSRVTINNW
FT                   VANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKEPFYKVDGQSCP
FT                   VPMMYQEGKFKYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEQELTPELLQEW
FT                   LDELSETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPEKSQLPGIVAGGRDDLYVSD
FT                   AFHKAFLEVNEEGSEAAASTSVVITGRSLNPNRVTFKANRPFLVLIREVALNTIIFMGR
FT                   VANPCVN"
FT   exon            <2901..2941
FT                   /gene="AT3"
FT                   /product="antithrombin"
FT                   /number=1
FT   exon            4740..5109
FT                   /gene="AT3"
FT                   /product="antithrombin"
FT                   /number=2
FT   exon            8836..9051
FT                   /gene="AT3"
FT                   /product="antithrombin"
FT                   /number=3A
FT   exon            10761..10898
FT                   /gene="AT3"
FT                   /product="antithrombin"
FT                   /number=3B
FT   exon            12828..13218
FT                   /gene="AT3"
FT                   /product="antithrombin"
FT                   /number=4
FT   exon            15537..15601
FT                   /gene="AT3"
FT                   /product="antithrombin"
FT                   /number=5
FT   exon            17856..>18032
FT                   /gene="AT3"
FT                   /product="antithrombin"
FT                   /number=6
FT   regulatory      18082..18087
FT                   /gene="AT3"
FT                   /regulatory_class="polyA_signal_sequence"
XX
SQ   Sequence 20993 BP; 5669 A; 4970 C; 4730 G; 5624 T; 0 other;
     gatccagctg tggggtattt tctcaattag tgatcaaagg ggaaaggccc cttgtgggtg        60
     gaaccatctc tgggctggca gtcttaggtt ctataagaaa gcaggctgag caagctaggg       120
     gaagcaagcc agtaaagaac atccctccat ggcctctgca tcagctcctg ctttctgacc       180
     tgcttgagtt ccagtcctga cctccttggt gatgagatgt aagctgaaca aaccatttcc       240
     tccccaactg cttcttggtc aagatgtttg tgcaggaata gaaaccctga ctaagacacc       300
     caaagtgaag gtaggagggc ctgcttcccc atggctttag cagcatgtgt ggtctagcac       360
     aaatctctca actctttcct ttctcttttg aagacaagat agccacaaat tcattgtgca       420
     gcctaggcag gcctcccaac cctcaaatcc tcagttttcg gagtatacta ctctctctct       480
     ctctctctct ctctctcccc ctctctctct cagacacaca cacacagagg gaggtagaga       540
     gtgaaagaga gagacaccat gaaaactgac taaattagca tgtgaaaata tgatgaaaac       600
     tagtaatata gagagatgtc taataatgtt ttgtatgcta cttacaaact tttaaaatgt       660
     catttcataa aaaggggaaa actaactttg caggtgaagc tttgctcgca gcaggttcaa       720
     acaagtaatg aaggccagat tttctcaaat taactggcct atgcactcaa aaatgccaag       780
     cctgctagac agagcaagct ggaagctcag gaagataact gggaggtaat ccttagtggc       840
     cacataaagg tgaggagaga accatgtcag cagagttgtc ctctgaccct cacacatgct       900
     ggtgccaggg ttacccgtaa tcacacgcat gtatcataca cacacacaca catccttaag       960
     tgtttgcttg tttgttgtgt atgctctcac aaacatgcta cagtgcagat ggaggtcaga      1020
     ggacatctgt gggagtcaga tttcttcttc taccacgtgt gtcccaggga ccaaactcag      1080
     gtcatcgggt tggtagcaga tgcctttacc cactgaggcg ttgtgctgtc cctatcccca      1140
     ctttttgtat gttggttaca tacatggctg ctctctaacc catgcagatg cctgcagctc      1200
     agaacatatc cctctattgg ctaaacaggt gatgtttgtc tttagtcaag agtaatgatg      1260
     ggcctttgag caacaaattc tggcatccat ccttgaattg tcccgctcag tcaggcaaga      1320
     cctttgctgt gacttcagac ctaatgagtt cctgtctaga tagtgaagca ttccccacaa      1380
     ttcctcacac agaatgctga acacagagca atcctagtga ggaaaaccga gataaaggag      1440
     cctcctatct ccacttagct tgaatttact taacccctgc ccccagaact actaaaaata      1500
     ttaataataa tatgtacaga cataatttgg cttgttcgct ctttaagaca tatttcgagc      1560
     caggagttgg tggtgaatgc ctataatctc agcagtctgg agcagaggca ggcagatctc      1620
     ttgagttcag tgccagcctg atctacagag tgagttccag gacagccagg gctgcacaga      1680
     gaaaccctgt ctcaaaaaga ccttaaaaaa aaaaaaagag gtgttttggg ttgtgcagag      1740
     tcgccaccat gagaaaggcc ctcctgaact gaactgaact gaactgtatg gacaagaagt      1800
     tcttattgaa gtgaaatggt ggcagacatg tccaagggat gaatggcgaa tgatgagtgt      1860
     ggagagcaga agcaacactg agcaacagag caaccttgca atggtggtcg ccaaggaaac      1920
     agcatcatca ggcagaagcc ttggagagag tctaaacaac ggccctgcac cttcagcagg      1980
     agtgcaccca ccccaccccc aacacacaca cagggcctgt ctgactgtgg gtgtagaact      2040
     gggtcatgga cattttcata agaaactctt ttgtttgttt ggtttggttt ggtttagttt      2100
     tttgtttttt gagacagggt ttctctgtag acccctggct gtcctggaac tcactctgta      2160
     gaccagggtg gcctcgaact cagaaatccg cctgcctctg ccttccgaat ggtgggatta      2220
     aaggcgtgtg ccaccatgcc cagcaagaaa cttatttcta aataaacttc tgtgatactc      2280
     caatattaaa aaaagaaaaa aataggagag gaaaggaaac gatttcggta gttgctgctc      2340
     ttgcgcacag taggcgaagc agatgcagag gctcacactt gtaatgccag cccttgggag      2400
     gtagagacag gagagcagat gtccaaggtc agccttagat acataacaaa cctgaggcta      2460
     gcccgtcaga ggcaggcagg gagcagaaca agcaggtgtt ccccgtcatc ggcctccgcg      2520
     tctgcactct cctgacttga ggcaccaggg cttttcccca cagagccctc ttgagtcggg      2580
     aaccccctca gtggatctga gtcctccatg tgcccccctt ttcctttcaa agaagagaga      2640
     agaatggagg gctgcgggca agaagagggg gacacacctt ccctaggcct gagtgaactt      2700
     taccttgtct actaattaaa caacacggag ttctgtgctt tgcttaaccc tgggaaccgg      2760
     tcatcagcct ttgacctcag ccctcctctc ctgaccagct ccctccccca cctggcctct      2820
     ggacctctca gatttagggg aaagaaccag ttttcggagt gatcgtctca gtcagcacca      2880
     tctctgtagg agcatcggcc atgtattccc ctggggcagg aagtggggct gctggtgaga      2940
     ggtaagcggt gggcttccct ctgtcagctc tggctgggtt ttctgacctc tgaaggactc      3000
     tcaaggatga cctctgacat ttttgagacg accaggccct caccctagta gttagtcaaa      3060
     gaccttttgg aagccatcac ttcacctaag ccacacctga ggttcttagc tcctttagaa      3120
     gccaagggtg cttcccttgg gaagagatgg gtaagccaga gcgcacttcc agggcagcct      3180
     cctaatctgc tcctcttcct actcaactgc cccccacctg ccactgtgac ctccgactac      3240
     ctcccaaagc ctccttcccc tttctccctt cttggtgtag gttgttgctg taggttgcta      3300
     aaaatgaaga ggtagcctga ccattatggt tcctgtttat acccagcaga gcttaggacc      3360
     cctcctgctt ctattcacat ttccagatgt gcccaagaac aaaatgggaa agacaagaca      3420
     acagcgaggc tctctctccc cttcctcact cctctctccc ccctccctct tccctcttgt      3480
     cactctacct gttgatatca gaccacacaa aaattccaag catccctttg ggttggccct      3540
     taccccccag ttagaccatc tcccactgag cagcctacct gcctgacttt ttcttccaga      3600
     agggactgga aaggcgcaat gcttagatac agactccctc tccttaccca ggtaccccag      3660
     agcacctgga gggagagcat ttacttcttg gttattactt tattgagtat ccacattctc      3720
     ttgccaatct cactacttca tgtttttaac tgaggtataa tgtagcccag gctgccctcg      3780
     tgcctgttac cttagcctcc caaatgctga gattaaggtt gtaaccctca ccatacctgg      3840
     ctactagctc agttttttag aacgagatac caagctgggc atgatagtga atgcctataa      3900
     tcccagcact tgggagctgg aggaaggaaa gtcagaagtt taaggtcatc ctcagctaca      3960
     tagtaagaat ggggcagcct gggctatccc tgacaccctc aaagtgagat tacctttact      4020
     tttagtgacc cttgttagaa gctattaaaa catttcagga gacagaaaat aatgagggca      4080
     gaactaagga gggggcagta gaggtcagag ggtaaggaag gagaattcat tgaatctggg      4140
     atctgactca accaggaggg ggaggggaag gagctgggtg acttctaggt ttctggactg      4200
     gtgtcaggat ccactgggtt gaaggataga agagcaggtg tgtgggggag gtgacagctc      4260
     agcatgtcac atctcactat ggaagtcgct ggccttccag accgaactgt ccggccaata      4320
     gtaagtctgg ctgtctgcgt gcaggctgga gctgcagatc tggggccttc tgtactcagc      4380
     tgctccttcg ttgagttcac attctcttac ccattttcgc caaagccagt ccttcaagat      4440
     tcaggctaaa gtctgtcctt gtctggggtt ttctgacccc ttcaggtggc tcccttcaca      4500
     ctctcgactc tctctactgg gctcatgtgg gcgttccgtt catcaaaggc agcgttgcgt      4560
     tcttttttag cctagcatgg acacacacac aactgtgtcc aggcaaggag cctaggactg      4620
     gttttgtcct agatggacaa ggatgcttag ctcaaacgtc aaggccggaa tcctacactt      4680
     tcaggaataa gactgtggtg gtcagtgggg atggggagtc atggttctgt cccttgtagg      4740
     aagctttgtc tcctctctct gctcctcatc ggtgccttgg gctgtgctat ctgtcacggg      4800
     aaccctgtgg acgacatctg catagcgaag ccccgagaca tccccgtgaa tcccttgtgc      4860
     atttaccgct cccctgggaa gaaggccacc gaggaggatg gctcagagca gaaggttcca      4920
     gaagccacca accggcgggt ctgggaactg tccaaggcca attcgcgatt tgccactaac      4980
     ttctaccagc acctggcaga ctccaagaat gacaacgaca acattttcct gtcacccttg      5040
     agcatctcca ctgcttttgc tatgaccaag ctgggtgcct gtaacgacac tctcaagcag      5100
     ctgatggagg tacagtgtaa agccctcttc ctctttcctt gcgggggggg ggggggggcg      5160
     ggggggggag cgtctcttgg atctccttat gtcgcacatc cgcttgtcta ggggatctca      5220
     ctgtgggtta tgattttctt tgaatcagta tttcatgtgt taggatattt tttctttttt      5280
     ttttttaatg attttttttt atgtgcacag gtattttgcc tgcatgtgtg tctgttggat      5340
     cctctggaag tggggttaga gacagttgtg agctgccatg tgggtgctgg gaattgaacc      5400
     ctagtcctct ggaaaggcac ccagtgatct taattgctca gccatctctc cagtccagga      5460
     ttctttctct ttctttcttt ctttctttct ttctttcttt ctttctttct ttctttcttt      5520
     ctttctttct ttctttcttt ctttctttct ttctctctct ctctctctct ctctctctct      5580
     ctctctctct ctctctctcc cttccttcct tccttctttc cttccttcct tcctttctct      5640
     ctctctctct ctctttcttt ctctctttct taaatactct agtttttgag agttttgagg      5700
     attttttttc tgtgtagccc agggtgaccc caaagttact catatgtagc tctagttggt      5760
     cttgaacttg tgatgattgc ctggcctcag cttcatgaat agaagaatta caaatgttag      5820
     ctatcatgtg gttaactagg caaggagtta ttacctggat gtcttcctca taaatgtttc      5880
     ctattctctc ccatataaaa tgttttttac ttgttattat ttgaggggag cacacacgcg      5940
     catccatgta cacggagtca gaggacaact ttcaggagcc agttccttcc tccttcctta      6000
     ttgatggagg tccctcattt ctgcacactg catggtccag gctgccctgc aagcttccag      6060
     gagacctcta ttccgtattg ctataggggt gttgggatta tagatgcaag actatatagt      6120
     ggcttttttg tgggttccag ggaccaagca cagattgtca agcttgataa gcaatgcttt      6180
     tatctgctaa cttatcttgc tagctcacat tgtgtgctat tcataaacag gagaaggctg      6240
     ggattaccac tcccttttca gtcatatttt ctctctctct ccccctcctc ttcctcatat      6300
     ttcttcttct tcttcttctt cttcttcttc ttcttcttct tcttcttctt cttcttcttc      6360
     ttcttcttcc tcttcctctt cctcttcctc ttcctcttcc tcttcttctt cctcttcttc      6420
     ttcctcttct tcttcctctc ctcctccccc tcctcctcct cctcttcctc ttcctcctcc      6480
     tccttctctc tctttctgtc attcattttt aagacaatgt ctcacaatgc ttcactcatg      6540
     ttgttcttga acttggggtc ctcttgtctc tacttctcaa gtgctgggat tgcaggtgtg      6600
     tactatgtcc agttatttgt atattcattc atttgaccat ttgtatgttg gttttttttt      6660
     ttaaatctag cactatctct atgctggggc catatgctgg gtgaatatcc tattccctgc      6720
     cctggtaggg aaagacaatt tgccatctag tgaactgaag cagattggct cttggggttg      6780
     attctagggc tctatatctc tatataatga gacctggatc ccaggaagct gagaagccac      6840
     aaagaaacag actgtttgga gctatgggca gtaatgatca cttcagtact gccacccgtt      6900
     tttgtcaggt cagggaagag gttggccctg gtatcactct aaaccgtggc tggaaacacg      6960
     agatccttac tctgcccttg gctttcttca ggtgggatct cactgtggaa acaaagataa      7020
     gcgacaggga ggcagaagcc cctgcagcat gtcatacagt gtcctcagaa cccaagacac      7080
     agatgtctgg agttagaaag gtttcctttc ctctcctcaa gaggtcagtt ccactgaaca      7140
     ccactcatgt gttcagacgc aggcatgcgg ctctgtattc tgcatctgct gtccccagca      7200
     caacacacaa gagactgtcc ttgccgcatt ctgtgttcct gttgctcttg tgaatgaatg      7260
     gtggatggca gcacattaga actcccctga ggcattcgta cacacaggca tcagtctcaa      7320
     gcatctcctt atagtctgtt gctgttccct gaatgtgagc ttaaacatga ccttccctat      7380
     aaaaatcaac aagagctgga gatgtggctc agtggtagag cacttggcca gtaatatgca      7440
     gaactcgggg gttactctct attggtgcaa aataaaacca gaaagaaaaa cccaccagag      7500
     gcagaaaaac attgctaatc cacacacgtc ctctgagtcc cttctacata tcttacaatt      7560
     tatgatgtca aatatagaaa aatgggtatg attttctttc tctagagcaa agagaaactt      7620
     atagagcttt tagtcacaga taaaaggaga cctgtgagaa ggccaattgg taaagtgctt      7680
     caccttgcat gtaccaagtc ctgagtttga gctctagaac ctatatacac aggcatggtg      7740
     cacatttgtt agctccaggg aggtagagat aggcagatag accccttgcc aggcagccat      7800
     cttaccctag tcagctagct ctagaccagt gagagcccct gacttacaaa gtgggaagtt      7860
     gggtctggag agacagctca gagattaaaa gagctcccct ctcttccaga ggacccagat      7920
     tagatgccca tcatccacgt ctggcagctt ataactacct gcaaccccag ctccacaaag      7980
     tccagtgccg tcttctggcc ccttgaggca ctcacatcta cgaggcactc tttcaccacc      8040
     ccaaaataaa tacagttttt ttaaaaagga aaagaagaag gtgggtggta cctgagtaac      8100
     aatattcgag ctcgtcctct gacctctctg aacatgtgca tacatgccca cgtggtcatg      8160
     ggcacacaca caagcacaga gtgcttatca ggacaccagg aaaacttaag aaaataaaac      8220
     caaaaggcct tttccacctg aggagtgagc actgagagct gcaggaagca gcctcaccat      8280
     tttgtgctgg tgatgaagaa ggtggttgtg tgggtctatg gcagcttcta aggctctgac      8340
     tggcatgtgt gtggttccta agccctttct aagcctgaga ctctgattct gggttcattc      8400
     attcccttct gacacaatct tttcttctct cagcccttct acaacctgta ttccagaggc      8460
     ccccagaatg ccgacccacg caaatgctgt gagaacgttt cgaggaggtg cactaccttg      8520
     gttcctttag gtatctgtaa ttaccaagag gacgtctccc ttcacagtga gaaagcaccc      8580
     tgcattggtc tacagccctt taaagaccca gtggcgttcc tgtctcttgt tctttcccaa      8640
     ttatgtttcc tgtcttttgt tctttttttc ttgcatattt gtttttagaa catgagctga      8700
     gtgtctatgc tgtgccaggt actgtgctgg agtgagctaa cagctgagat ggcccttgga      8760
     ccagcactgt attctgcacc catggtaact gactgtccaa ctacaccacc accattttct      8820
     ttttgtcatc tataggtttt taaatttgat accatctccg agaagacatc cgaccagatc      8880
     cacttcttct ttgccaaact gaactgccga ctctatcgaa aagccaacaa gtcctctgac      8940
     ttggtatcag ccaaccgcct ttttggagac aaatccctca ccttcaacga gagctatcaa      9000
     gacgttagtg aggttgtcta tggagccaag ctccagccct tggacttcaa ggtgagttgt      9060
     aggtgacaga gtccctgcca ctcgcactaa gaagggagag gaacaggatc cagaggaaca      9120
     cgaccctact tgccaatggc tggtggaggt tgaggacaaa tcagaagcca cagcacacac      9180
     ccttggttaa ggcttcacag agccacggtc ctcaagcgtt cagatataga ggctactctt      9240
     aagacgctgt acaagggatt actttttcat ttcatctacc aagttcagat atgtcacagt      9300
     caaataaaat tggtgcatga tgcatgttcc atgctccctc ggagattcag gaagcacacg      9360
     agcctagtaa gtgttttgag gaagtaatac agcaaagaaa ttccttgatt tctgttgtag      9420
     gaaaatcctc taaaaggaag catttcattg gggggcttaa ttacaacctc agagcgttag      9480
     tcatttcctt tatggcagga agcatggcgg caggaagcat ggcggcagac aggcaggcat      9540
     gggcttcaga atttactttc taattcatag gcagacagag aaattgagag atgctaggac      9600
     tggcaaagcc cattcccagt tatgcatcta atcctcttaa ttcttttcag aaatccttaa      9660
     tcaaaggggg actaagcggg cacatttatg agcctctggg gctgttttca ttcaaatctc      9720
     cacagcatct ttctgtcagc attttctttt cttttctttc taccccatcc cccatgtcca      9780
     agcccccaga cagggtttta ctatgtatcc ctgactgact tggaactcaa ctctgtagac      9840
     catactggcc tccgactctc agagatatgc cttccgagta ctggaattag aggtgtgagc      9900
     caccgctagc tggtcagcgt tgtctacatt tctttgacta cagggcgctt ggcccctccc      9960
     atcttcttaa ccttatttcc tcccacagac tggagatgat gcttctctga gtttagggtt     10020
     tccagagtca gagtaggtac catccttacc ttccatccgc cagcctgtct gcccctttca     10080
     tctgccctgt gtctcctcct ctttcttctg ctgcttataa catttattga tgggctgggc     10140
     tctgagtgtg agccctgtcg tgacaaagga ttaagtgcat ggaaaaacaa aacagccggg     10200
     tgtggtggca cacgccttta atcccagcac ttgggaggca gaggcaggaa gatttctgag     10260
     ttcgaggcca gcctggtcta caaagtgagt tccaggacag ccagggctat acagagaaac     10320
     cctgtcttga aaaaccaaaa aaaaaaaaaa aaaaaaaaaa gaaagaaaaa aggaaaaaca     10380
     aaacaaaaca aaacaaaaca cagtgactgt atcgggcgac tgagggctcc tcggtgtggg     10440
     ttaaagcaat ggcttccctt ttttgtttgt tttgtttgtt tgtttgtttt tcaagacagg     10500
     gtttctctgt gtacccctgg ctgtcctgga actcactctg tagaccaggg tggcctcgaa     10560
     ctcagaaatc ctcctgcctc tgcctcccga gtgctgggat taaaggcgtg cgccaccact     10620
     gcctggcaaa gtgatggctt cttaaccaat catgggaaaa gaacgagcaa atggcgggca     10680
     acggaaatgc tgtattgaga acttgacagt cagagctaac gagtcgaata ggtgggtaga     10740
     ttattttctg ttttccttag gagaatccgg agcaatccag agtgaccatc aacaactggg     10800
     tagctaataa gactgaaggc cgcatcaaag atgtcatccc acagggcgcc attaacgagc     10860
     tcacggccct ggtgctggtt aacaccattt acttcaaggt acgtcagctg gtcctggagg     10920
     gatgacaggg acttcttctc actattactc tattaagcac gtgtagtcaa atccctcctg     10980
     aaatggtcca tgcacggtct aggcaaccat ataaatttgc tgaaagccca gaggtccaga     11040
     ggcttagtag tgtccccagg ctggggcaga ctatgtgaac gtactaactg aggattcttc     11100
     aagatgtgac aaattttcac acttgtgtga caatttctgc cattcaatta atattttctt     11160
     ttttaaattt caagactggg tattatgtag ccctggctga cctggaactt gctaagtagg     11220
     cctggccttg tgttcacaga gagattcacc tgcctctgtc tcccgagtgc tgggattaga     11280
     ggcaggtccg ttaatgtatt taaaatcaga aaataaatga ttttactgac aaccgtcagc     11340
     gatagagttc cccactgcca agagcaattt ctacttaaca tgtcccctag gggttcggaa     11400
     gctcctgtgc tgggctaccc agaataagaa ggggcctggg acagtaccat gttatggctt     11460
     gtttcctcac agcccagggt tctgagaact gcttcagtct gatttcaatt gaaacagagc     11520
     agggggagga tattggaaca aatgctatca gcactctgga ggactgtccc tgcagagcag     11580
     taactgtgat gtgttgttta tcctcagaca tgcgctgttt gcattcctcc tttctccatg     11640
     tggcctggag acttagccag ccatggctat tgtcagtcac tgcctcttgg agcctccctt     11700
     tccccagaac agagtagact gcatttccac agtgtgttgt ttgttacccc ttacagttta     11760
     agcggcaact tgctatttat taatattcta gatcatcata ccactgagag tgagaccatg     11820
     ggctgtttgt gccatatgat ttctttgttt taaagattgg ctcctcattt ctaagtgtat     11880
     gaagtcatgt gaattattgg ggagttactg ggaactttcc tatggcctat ttctgtatgt     11940
     ataaaatggt aatgaggatt cacctacttt ataggcttac caaaagggtt cgagtaggta     12000
     acacaggtga catacttagg tgttatacat gcttagagca cacagttaac attgtaaagt     12060
     cattggctct ttctagtacc taacttgtgg gtgagaaacc acctctcaga agggttaact     12120
     gacttatctc aaagagccag agaaccataa ggaatgaggt aggaagccag ccaggagcca     12180
     ttcccctcct ggcaggactt ccagacaaat cgcagggatt gctgtctgag tctggcctct     12240
     aactcagcag ggacaaagca cagagttctg aagatcggct ctggcaaaga ggctgataga     12300
     gagcagacaa gaggcaggat gaacttgcaa aggagagtgt aggttattct aagggttaga     12360
     ctctcctgac ttaaaacaac aacaacaaca acaacaacaa caacaatacc aacaacacaa     12420
     tatcaggctg gcaagatggc tcagctggta aaggtgctgt caccatacct ggcaacctga     12480
     gtcccatcgt ggagcccaca tggtaggagg aaagaaccgt ttcctgaatg ctgataaatt     12540
     gtcctttgat gtccacatac ccatagtggc acactcctcc tctcaaatgt taaaaaaaaa     12600
     aggtaatatt gatggaaata caaaaaaaac ccacagaatg agacacacat aaataactgt     12660
     accactcaga tatagacatt agccttttaa tgcatatcta cttttttcta ataactacat     12720
     ttatatgttg atgcaatcag ataatatggt tatgtcccat atcaataagt atcctggtag     12780
     gatatttttg ttcttgcttt atgattctcc cacttgacat ctttcagggc ctgtggaagt     12840
     caaagttcag ccctgagaac acaaggaagg aaccgttcta taaggtcgat gggcagtcat     12900
     gcccagtgcc tatgatgtac caggaaggca aattcaaata ccggcgcgtg gcagagggca     12960
     cccaggtgct agagctgccc ttcaaggggg atgacatcac catggtgctc atcctgccca     13020
     agcctgagaa gagcctggcc aaggtggagc aggagctcac cccagagctg ctgcaggagt     13080
     ggctggatga gctgtcagag acgatgcttg tggtccacat gccccgcttc cgcaccgagg     13140
     atggcttcag tctgaaggag cagctgcaag acatgggcct cattgatctc ttcagccctg     13200
     aaaagtccca actcccaggt tggtatagga gagatgtgct tgcctccttt ccactccaag     13260
     gtggtttaac caaaagtgag agaatccagg aaagtccagg gaagagtgcc aagtcagggc     13320
     accaggattc tgatcgtggc tctgtgctaa gctcagggtg atcccttgcc cttccaaacc     13380
     tccctgtgaa agagagtttg ctcttgtttc caggagtcca acaagtatgt ctgtcacccc     13440
     cgggatctgt atctaacagg ggagatcaaa ccaggtgggg aagaattcgg aaaagcattg     13500
     gaattcaaag aaacagacat taaaagcaat gcatattgag acctataatt ccagtactgg     13560
     ggggtagggt agaacacaga gtgttccagg acagcctggg ctatagaaca agatcttgtc     13620
     ccaaaagtaa ataaaataga gcctagagag acatctcagc agttaagagc ctgtagtatt     13680
     atcattgcag aagactcagg gtcagcttcc agactccacg gtagacagct catgacccca     13740
     caggcacctg cactcatgtg cgcgcacaca cacacacaca cacacacaca cacacacaaa     13800
     cagacacaca aacagacaca caaacagaca cacaaacaga cacagacaca cgtacacaga     13860
     cacacacaca cacagacaca cacacacaca gacacacaaa cagacacaca cacagacaca     13920
     caaacagaca cacacacaca cacacacaca cacacacagc cacatacaca cagccacaca     13980
     tacacagcca cacacagaca cagccataca cacacagaca cacacagaca cacacacaca     14040
     gacacacaca cagagagaca cacacacaca caatcttgaa taagataaaa atgtgatagt     14100
     aaattaaaat taaaaacaaa ccttagctgg gcatggaggc gcatgccttt aatgccagca     14160
     ctcgggaggc aaaggcaggc agatttctga attcgaggcc agcctggtct acagagtgag     14220
     ttccagaaca gccagggcta cacagagaaa ccctgtctca aaacaaacaa acaaacaaac     14280
     aaacaaacaa acaaaacaaa aacccccaaa caacaaaaca aaaaacccaa acaaacaaaa     14340
     caaaacaaca acaacaaacc ccagcacttg agaggcagag gcaggaagat ctctgagttc     14400
     gatgggggtc agcttgattt tttttttttg ggggggaggt tcaagacagg gtttctctgt     14460
     gtagccttga ctatccatga aacttactct ctaaatcaag ctgaccttat gccgggcgtg     14520
     gtggtgcata cctataatcc cagcacctgt gaggcagagg caggcagatt tctgagttca     14580
     aggtcagcct ggtctacaaa gtgagttcta ggacagccag agctatatag agaaaccctg     14640
     tctcgaaaaa caaaacaaac aaacaaacaa aaaacaaaaa aaaaaaaaag aaaagaaaaa     14700
     aacaaaataa gtaagtaaat aaatagttaa ttttaaaaaa ttagccttaa aataccttct     14760
     taccttttta tttatttttc cattgagaca gggtcttatg cagcccaggt tagcctggta     14820
     cccactgtgt agctaagttt ggctttgccc tgattgtgct gtctccaccc tgagagctgt     14880
     ttaattcctt ttatcatgta aacatggtgt accactacgc ctagcaagat cttttactta     14940
     ttaatacatg tatttatttg ttgttatgta tggtatgtgg agaggaatgt gtaagtgtgt     15000
     gcatgggggt cagaggacaa ctttaggggt tcaaagccac atggagccct gggattaaac     15060
     tcaagttgtc agggttagtg gcacattccc ttacccgatg agcaatctca ttggcccgca     15120
     gagctgggtt cagtggcaca caattgtaat ctcagccctc caggctgggg caggatgaca     15180
     gtttaaggcc agctcaggct acacaaagat cctatctaaa aattacttag acttaggtaa     15240
     ttagattttt ctttattggg ctatctttag ctttgagagc caaacctctt aaaaacgtta     15300
     ccatactgga aagacatatt tttgctagat atagtaaagt ttttgagagc agagtcccac     15360
     ccttccacct tctcaaaaaa gttgacatca gattaagttc acaagatcca ggtcaaagaa     15420
     gccaaaatga atcagttttt aagaggtatc cattgagggg gtgaggggta ttattaggga     15480
     ggttcagcag cctgcttctc aagacacagc cccccctccc cttcttgttc ttccagggat     15540
     cgttgctgga ggcagggacg acctctatgt ctccgacgca ttccacaaag catttcttga     15600
     ggtgagttca gttccctcca cccgctgcct ttttttttgc attttatcaa tctgtgttcc     15660
     tggagtttct tgctgctctt ctggtggaga cagctggtct attagcagca gaggattgtg     15720
     gcagaggcat ctcggcaggg tccctctaaa tcatgtacat atggagaagc ttgtagcctc     15780
     cgccatgagg tctgcctcag gatggcactt caaaggagcc ctcaagcttt gactgtttgg     15840
     ccttctctcc tgctagagag acatagaggg tagcccaagg aaaaggagcc aaaggagccg     15900
     gcaaaggcca tggagaggga attctgagat gtttcaggaa tgtgaaaagc atggagtaag     15960
     actgaaaccg attctggaca gaatggggag ggacacgtgc gtaagtgaag aaggtgaaga     16020
     acaaatgaac ataagacagg gggttgctaa tgagtatggc tcaccttagc gtcaagggcg     16080
     ttctagatct agaacaatct tgtaatatat agcatttcag gaaactcagt taggtgggca     16140
     catgttgatc ttcttgggag attaactaca cacagtggta tgctgagact gagaagtccc     16200
     agggaggaaa tgggtagagc actgatgagc ctgtcttccc ccaactaagg tgcacataga     16260
     attgtatgtt agccaagtag tgacaggttg tagaaattct cgttcttagg tactgaagtg     16320
     tggaccgtaa aggtggggat ccttaaccct ggaggctgaa ggatggaatc taggaatttt     16380
     tttctttttt ctttttggtt tttttcgaga cagggtttct ctgtagagcc ctggctgtcc     16440
     tggaactcac tttgtagacc aggctggcct caaattcaga aatctgcctg cctctgcctc     16500
     ctgagtgctg ggattaaaag cgtgcaccac cgctgcccgg cgaatttttt ttctttttgt     16560
     tgatttgtgt tttgagaaaa gttttcttcc tgtagccctg gccatcttga aacttgttga     16620
     gaatctgttt cttaacacag atccttggga gatttttata agtaggttcg aggtccagtg     16680
     gtgtaggctg ttcttcgtgg aagctaagac tgtgagcaga agggccaacg atagacaaag     16740
     ctaacaggac ttgggtttgc aaagaaaggc tgcaattaga gagaaatatc cagagtatgg     16800
     tgccagagaa ctaattctag gatccaagca agcttagtgg caacttaagg aagcagaagg     16860
     tgagggacag gaggtgagaa cttgctgaat tgcaacttca catcacttaa atttagtccc     16920
     agaatgagca tgaaatagat gtgggacacc aaagggaagg aaaaaaaaaa aaaaaaaaaa     16980
     accccacatt aaccagcccc tcaaaacaca gagattgcaa gtactttatt aatagttagg     17040
     gacaggaggc caaggcagga gaatttccac aagttccagg ccagccttgt ctatatagaa     17100
     cattaaaggc tagcaaggtg tacacacaca cacacagagg ccagcctggt ctatacagaa     17160
     cattaaaggc tagcaaggtg tacacatgta cacacacaca cacacacaca cacacacaca     17220
     cacacacaca cactgggaat caggatctta aatggcaagc tagcctcggt actagaatgc     17280
     acagcaagat cctacccccg acaggtcagt atgtcaacag ttgtcatttt ctgaaggcat     17340
     cccttcagat gtgccattgt tcaaatgctg agtttttttt tttttttttt ttttttggtt     17400
     attactccaa aaaacccacc tcacttaact ggagaactat cttttcataa gccacaggtt     17460
     cttggtggct tttggggggt ggtagtgata gctgggattt ctttatgctt tgagagtgaa     17520
     tctatttaaa gtgcagatct tcaagtttga gtctgagttt tctcttcgca gttggtttaa     17580
     aacaatgcac tgttgcattc gacaatgttt aaccatgcta ccagaatgtg acttctagct     17640
     cagggattac acttgtggca ttcttgcaag gctttggatg agcccagtgc attgtacaca     17700
     ctggaggtta agaacagtag gtttctggag ggaaccattt gcgtccaggt gttagttact     17760
     agaaaccagc agtgtgagcg ctgggtctgg gtgtgattta tgtgcctagg gtggactgga     17820
     gggtagctaa tatttgtttc ctatgtgacc tgcaggtaaa tgaggaaggc agtgaagcag     17880
     cagcgagtac ttctgtcgtg attactggcc ggtcactgaa ccccaatagg gtgaccttca     17940
     aggccaacag gcccttcctg gttcttataa gggaagttgc actgaacact attatattca     18000
     tggggagagt ggctaatcct tgtgtgaact aaaataatct ttgcaccttt tcctactttg     18060
     gtgtttgtga atagaagtaa aaataaatac gactgccacc tcacgagaat ggacttttcc     18120
     acttgaagac gagagactgg agtacagatg ctacaccact tttgggcaag tgaaggggga     18180
     gcagccagcc acggtggcac aaacctatat cctagtgctt ttgaaggtag aagcagggcg     18240
     gtcaggagtt aaggccagtt gaggctgggc tgcagagtga aagaccatgt ctcaagatgg     18300
     tctttctcct ccccaaagta gaaaagaaaa ccataaaaac aagaggtaaa tatattacta     18360
     tttcatctta gaggatagca ggcatcttga aagggtagag ggaccttaaa ttctcattat     18420
     tgcccccata ctacaaacta aaaaacaaac ccgaatcaat ctcccataaa gacagagatt     18480
     caaataagag tattaaacgt tttatttctc aaaccactca catgcataat gttcttatac     18540
     acagtgtcaa aataaagaga aatgcatttt tatacaaaca atttcaagta tacattaata     18600
     gacttctcag attactagcc aagtcgctaa gatttcattc acattgttct taaagctgtt     18660
     caacgagaaa gcttttgcta actgctttaa atatgtttat ataaacccac atcttaactc     18720
     ttctttgaat ctccccctcc cttgaccccc gtgccctccc cccctccccg acacaatagg     18780
     gctccagggg ctctaggaga catgctgccc ctccaagaac gattggcttg tccagggaaa     18840
     gacagaatct acaggaggag agtcagggtc ccctgtcaca cagggggaac caagcccagt     18900
     acttagatgt gacacaattc tggataatat tttagtgcca ttgtttccgc ttgatttttt     18960
     tattccaaaa aaaaaaaaaa gaaagaaaaa gaaaagaaaa aggaacttac cacaaaacac     19020
     gattttttaa agatataatt tggcagctaa aaaaataatt cagtgaaaat aaaatttccc     19080
     ccagaaaaaa attccaaaat cagggtaggt attttgaact cttatttagt ggttcttttg     19140
     ccctttggca gggagcactt ggggacagct ttaaaaacgc gtcattttgt gttcacatta     19200
     agatatctga tcctggagca gcagctgcct agcctatgta aggccctggg ctcaatcccc     19260
     agcactatgg ggtaaaggac aaagaaatgt ggttaaaccc aacaaggtct ggcaacagtt     19320
     ttccctcagc ttccctcctg agtgatctgg cttcagccac actccttagg aattaaagtg     19380
     catacttctt gtttttgttt ttttgttttt tgtttttttc agtaaagggg aagggagggt     19440
     tcacatgtga tgattgaaga aggcttgggg ggggggagaa catcctactc ctatatatag     19500
     gtatttatag ttaaggtcac aacagaaaac agtcttagga gacaagatgc acacagccag     19560
     ccccgccttc tcagaggtat gggagcgcta ccctgcggta ttttctgtat tttctgaggc     19620
     atctttacta ttaacggcat aactgttgca gatgtaagac acacatctca agtgttagac     19680
     tcttttcata gggagaaaac agactgggag ttaacaataa tctaccccat tcccacccag     19740
     gaccaatgtt ttagaaagtg attgtctctt tcggtataga ctctccttga ggaactagtg     19800
     ggaactagtc agatacctgc tgctttcaaa cgctattgcg gcagcttcag aaactggagg     19860
     aggctgcagt ttgattccca ctgtcactca atagcagctg aagtgaaatc tttttgtgat     19920
     ttcgtaatgt gacaactata acccaaatct aattgtttcc ctctgttttg cggaggtttc     19980
     ttgggatgaa cccccgacgt tctcaaagag aagttcctgc tacattagaa gctgtgtgaa     20040
     gaagaaatgg gctcaagaga agaagaggga tcttgtcctg ggttctggcc tctgagtcca     20100
     gtgtgatcct atttttcaca gtgaccagtg ggaaggcaca gtgccaggga caggtagccg     20160
     ggagacagct gtcacccgtt aaataagcac cagagaaaag agttggatat cgttccttcc     20220
     ttcagaatag gtccatctga agggaatcaa aggtctgctg cattgctgtt cctctcttgc     20280
     cctcacctcc tctgcctttc acaggcagtg ccagagtagc ccatcctaaa caacaggcac     20340
     caggaaatgt aagcgctctg ccaacgcact ttccctcact agggagaccg agaaccctca     20400
     gtgcagagcg ctgctgctaa gatgtcttaa aggaaaagga agtgactgag tcctgagtaa     20460
     tcgatccatt agaacataaa acagtgagga ggccaaagct gtgagcagac cagcaggtga     20520
     aaacggaccc tgggagcaca gagcgcactt ccttggccta tagatggcac ttgttttcct     20580
     caaggaccag gggatggagc tagggggtca cactgggatc agaccagcac ttgcttagct     20640
     gttgcagaaa gatttggatc tggaatgaca gttcagtggc agagtgctta ctcagcatgc     20700
     tgcagattct tgggctcaac acccagtact aaaaggacaa agagctatgg ggcaaaggaa     20760
     ggggagtgag tgagtgagtg agtgagcaag acaacacatt agggcagaag atgatctgac     20820
     tttacatttg tggtagaaat tttttactct tgctcaaaat atcaaatgct gacgtttacc     20880
     ttttcccacc actccccacc tttgtgtttt gtccagtgtg gtataatttg cataaactgc     20940
     ataaagtttc acagtactcc accatgttct ccagcacgaa catcccttct aga            20993
//