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EBI DbfetchLOCUS AC_000022 16300 bp DNA circular ROD 28-AUG-2012 DEFINITION Rattus norvegicus strain Wistar mitochondrion, complete genome. ACCESSION AC_000022 VERSION AC_000022.2 GI:110189662 DBLINK Project: 12455 BioProject: PRJNA12455 KEYWORDS RefSeq. SOURCE mitochondrion Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. REFERENCE 1 (bases 1 to 16300) AUTHORS Gadaleta,G., Pepe,G., De Candia,G., Quagliariello,C., Sbisa,E. and Saccone,C. TITLE The complete nucleotide sequence of the Rattus norvegicus mitochondrial genome: cryptic signals revealed by comparative analysis between vertebrates JOURNAL J. Mol. Evol. 28 (6), 497-516 (1989) PUBMED 2504926 REFERENCE 2 (bases 1 to 16300) AUTHORS Grosskopf,R. and Feldmann,H. TITLE Analysis of a DNA segment from rat liver mitochondria containing the genes for the cytochrome oxidase subunits i, ii, iii, atpase subunit 6, and several tRNA genes JOURNAL Curr. Genet. 4, 151-158 (1981) REFERENCE 3 (bases 1 to 16300) AUTHORS Grosskopf,R. and Feldmann,H. TITLE tRNA genes in rat liver mitochondrial DNA JOURNAL Curr. Genet. 4, 191-196 (1981) REFERENCE 4 (bases 1 to 16300) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (17-JUN-2008) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 5 (bases 1 to 16300) AUTHORS Saccone,C. TITLE Direct Submission JOURNAL Submitted (23-JAN-1995) Dipartimento di Biochimica e Biologia Molacolare, Via Amendola 165/A, 70126 Bari, Italy REFERENCE 6 (bases 1 to 16300) AUTHORS Saccone,C. TITLE Direct Submission JOURNAL Submitted (23-MAR-1989) Dipartimento di Biochimica e Biologia Molacolare, Via Amendola 165/A, 70126 Bari, Italy COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X14848. On Jul 6, 2006 this sequence version replaced gi:58615676. Sequence Note: NC_001665.2 represents the reference sequence for the rat mitochondrial genome. In July 2006 the underlying sequence was updated to represent the Brown Norway strain based on the recommendation of the Rat Genome Sequencing Consortium that BN/SsNHsdMCW should be the reference sequence. In conjunction with this update, an alternate accession AC_000022.2 was updated to continue to represent the the Wistar strain sequence that was previously considered to be the reference standard. for seqs get included see V00681, K00434, J01436, X07479, X07482. COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..16300 /organism="Rattus norvegicus" /organelle="mitochondrion" /mol_type="genomic DNA" /strain="Wistar" /db_xref="taxon:10116" /clone="pSF2124." tRNA 1..67 /product="tRNA-Phe" rRNA 69..1025 /product="s-rRNA" /note="12S ribosomal RNA" STS 901..1616 /standard_name="PMC316374P5" /db_xref="UniSTS:272966" tRNA 1026..1094 /product="tRNA-Val" rRNA 1095..2653 /product="l-rRNA" /note="16S ribosomal RNA" STS 2340..2525 /standard_name="RH136367" /db_xref="UniSTS:210357" tRNA 2654..2728 /product="tRNA-Leu" /codon_recognized="UUR" gene 2729..3685 /gene="ND1" /db_xref="GeneID:7066247" CDS 2729..3685 /gene="ND1" /codon_start=1 /transl_table=2 /product="NADH dehydrogenase subunit 1" /protein_id="AP_004892.1" /db_xref="GI:110189663" /db_xref="GOA:P03889" /db_xref="InterPro:IPR001694" /db_xref="UniProtKB/Swiss-Prot:P03889" /db_xref="GeneID:7066247" /translation="MYFINILTLLIPILIAMGLLTLVERKILGYMQLRKGPNNEGPYG KLQPFADAMKLFMKEPMRPLTTSMSLFIIAPTLSLTLALSLWIPLPMPHPLINLNLGM PFILATSSLSVYSILWSGWASNSKYSLFGALRAVAQTISYEVTMALYLLSVLLMSGSF SLQMLITTQEHIWLLIPAWPMAMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAG PFALFFMAEYTNIILMNALTSIVFLGPLYHINYPELYSTSFMTETLLLSTTFLWIRAS YPRFRYDQLMHLLWKNFLPLTLAFCMWYISLPIFLAGIPPYT" tRNA 3684..3752 /product="tRNA-Ile" tRNA complement(3750..3820) /product="tRNA-Gln" tRNA 3824..3891 /product="tRNA-Met" gene 3892..4929 /gene="ND2" /db_xref="GeneID:7066248" CDS 3892..4929 /gene="ND2" /codon_start=1 /transl_table=2 /product="NADH dehydrogenase subunit 2" /protein_id="AP_004893.1" /db_xref="GI:110189664" /db_xref="GOA:P11662" /db_xref="InterPro:IPR000652" /db_xref="InterPro:IPR001750" /db_xref="InterPro:IPR003917" /db_xref="InterPro:IPR010933" /db_xref="UniProtKB/Swiss-Prot:P11662" /db_xref="GeneID:7066248" /translation="MNPITLTIIYLTTFKGRLITTLSTNLPPMWVGLEMSLLAIIPLL ANKKSPRSTEAATKYFLTQATASMIILLVIILNYKQSGMWTLQQQTNNMLLNMMLISL AMKLGLAPFHYWLPEVTQGIPLHIGLILLTWQKIAPLSILYQFYQLLNPTITTILAIS SVFVGAWGGLNQTQTRKIMAYSSIAHMGWMTAILPYNPNLTLLNLTIYILLTVPMFNY IMTNSATTINTLSLAWNKTPMILTMASIILLSLGGLPPLTGFLPKWAIISELLKNNCS TLSTLMAIMALLSLFFYTRLIYSMSLTTFPTNNNSKMISHHQNPKHNFILPTLTVLST LTLPLSSQLIT" tRNA 4928..4993 /product="tRNA-Trp" tRNA complement(4995..5063) /product="tRNA-Ala" tRNA complement(5066..5139) /product="tRNA-Asn" rep_origin 5140..5170 /note="origin of light strand replication" tRNA complement(5171..5238) /product="tRNA-Cys" tRNA complement(5242..5307) /product="tRNA-Tyr" gene 5309..6853 /gene="COX1" /db_xref="GeneID:7066249" CDS 5309..6853 /gene="COX1" /codon_start=1 /transl_table=2 /product="cytochrome c oxidase subunit I" /protein_id="AP_004894.1" /db_xref="GI:110189665" /db_xref="GOA:P05503" /db_xref="InterPro:IPR000883" /db_xref="UniProtKB/Swiss-Prot:P05503" /db_xref="GeneID:7066249" /translation="MFVNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQP GALLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSF WLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGVSVDLTIFSLHLAGVSSILG AINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTT FFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMGMVWT MMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKW SPAMLWALGFIFLFTVGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAG FVHWFPLFSGYTLNDTWAKAHFAIMFVGVNMTFFPQHFLGLAGMPRRYSDYPDAYTTW NTVSSMGSFISLTAVLVMIFMIWEAFASKREVLSISYSSTNLEWLHGCPPPYHTFEEP SYVKVK" tRNA complement(6850..6919) /product="tRNA-Ser" /codon_recognized="UCN" tRNA 6922..6989 /product="tRNA-Asp" gene 6991..7674 /gene="COX2" /db_xref="GeneID:7066250" CDS 6991..7674 /gene="COX2" /codon_start=1 /transl_table=2 /product="cytochrome c oxidase subunit II" /protein_id="AP_004895.1" /db_xref="GI:110189666" /db_xref="GOA:P00406" /db_xref="InterPro:IPR001505" /db_xref="InterPro:IPR002429" /db_xref="InterPro:IPR008972" /db_xref="UniProtKB/Swiss-Prot:P00406" /db_xref="GeneID:7066250" /translation="MAYPFQLGLQDATSPIMEELTNFHDHTLMIVFLISSLVLYIISL MLTTKLTHTSTMDAQEVETIWTILPAVILILIALPSLRILYMMDEINNPVLTVKTMGH QWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVL HSWAIPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKY FENWSASMI" tRNA 7678..7741 /product="tRNA-Lys" gene 7743..7946 /gene="ATP8" /db_xref="GeneID:7066251" CDS 7743..7946 /gene="ATP8" /codon_start=1 /transl_table=2 /product="ATP synthase F0 subunit 8" /protein_id="AP_004896.1" /db_xref="GI:110189667" /db_xref="GOA:P11608" /db_xref="InterPro:IPR001421" /db_xref="UniProtKB/Swiss-Prot:P11608" /db_xref="GeneID:7066251" /translation="MPQLDTSTWFITIISSMATLFILFQLKISSQTFPAPPSPKTMAT EKTNNPWESKWTKIYLPLSLPPQ" gene 7904..8584 /gene="ATP6" /db_xref="GeneID:7066252" CDS 7904..8584 /gene="ATP6" /codon_start=1 /transl_table=2 /product="ATP synthase F0 subunit 6" /protein_id="AP_004897.1" /db_xref="GI:110189668" /db_xref="GOA:P05504" /db_xref="InterPro:IPR000568" /db_xref="UniProtKB/Swiss-Prot:P05504" /db_xref="GeneID:7066252" /translation="MNENLFASFITPTMMGLPIVVTIIMFPSILFPSSERLISNRLHS FQHWLIKLIIKQMMLIHTPKGRTWALMIVSLIMFIGSTNLLGLLPHTFTPTTQLSMDL SMAIPLWAGAVILGFRHKLKNSLAHFSPQGTPISLIPMLIIIETISLFIQPMALAVRL TANITAGHLLMHLIGGATLVLMDISPPTATITFIILLLLTVLEFAVALIQAYVFTLLV SLYLHDNT" gene 8584..9367 /gene="COX3" /db_xref="GeneID:7066253" CDS 8584..9367 /gene="COX3" /note="TAA stop codon is completed by the addition of 3' A residues to the mRNA" /codon_start=1 /transl_except=(pos:9367,aa:TERM) /transl_table=2 /product="cytochrome c oxidase subunit III" /protein_id="AP_004898.1" /db_xref="GI:110189669" /db_xref="GOA:P05505" /db_xref="UniProtKB/Swiss-Prot:P05505" /db_xref="GeneID:7066253" /translation="MTHQTHAYHMVNPSPWPLTGALSALLLTSGLVMWFHYNSTILLS LGLLTNILTMYQWWRDIIREGTYQGHHTPIVQKGLRYGMILFIVSEVFFFAGFFWAFY HSSLVPTHDLGGCWPPTGITPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMN QALLITILLGLYFTILQASEYFETSFSISDGIYGSTFFMATGFHGLHVIIGSTFLIVC LLRQLKFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS" tRNA 9368..9435 /product="tRNA-Gly" gene 9436..9783 /gene="ND3" /db_xref="GeneID:7066254" CDS 9436..9783 /gene="ND3" /codon_start=1 /transl_table=2 /product="NADH dehydrogenase subunit 3" /protein_id="AP_004899.1" /db_xref="GI:110189670" /db_xref="GOA:P05506" /db_xref="InterPro:IPR000440" /db_xref="UniProtKB/Swiss-Prot:P05506" /db_xref="GeneID:7066254" /translation="MNLPIIITINITLSFILISIAFWLPQMNLYSEKANPYECGFDPT SSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQTTNTTTMMATAFILVTILSLGL AYEWTQKGLEWTE" tRNA 9785..9852 /product="tRNA-Arg" gene 9855..10151 /gene="ND4L" /db_xref="GeneID:7066255" CDS 9855..10151 /gene="ND4L" /codon_start=1 /transl_table=2 /product="NADH dehydrogenase subunit 4L" /protein_id="AP_004900.1" /db_xref="GI:110189671" /db_xref="GOA:P05507" /db_xref="UniProtKB/Swiss-Prot:P05507" /db_xref="GeneID:7066255" /translation="MTSAFLNLTMAFTLSLLGTFMFRSHLMSTLLCLEGMMLSLFVMT STSTLNSNSMISMTIPITILVFAACEAAVGLALLVKISNTYGTDYVQNLNLLQC" gene 10145..11522 /gene="ND4" /db_xref="GeneID:7066256" CDS 10145..11522 /gene="ND4" /note="TAA stop codon is completed by the addition of 3' A residues to the mRNA" /codon_start=1 /transl_except=(pos:11522,aa:TERM) /transl_table=2 /product="NADH dehydrogenase subunit 4" /protein_id="AP_004901.1" /db_xref="GI:110189672" /db_xref="GOA:P05508" /db_xref="InterPro:IPR000260" /db_xref="InterPro:IPR001750" /db_xref="InterPro:IPR003918" /db_xref="InterPro:IPR010227" /db_xref="UniProtKB/Swiss-Prot:P05508" /db_xref="GeneID:7066256" /translation="MLKIIFPSIMLLPLTWLSANKKIWTNVTSYSFLVSLLSLSLLWQ NDENYLNFSVMFSSDPLSTPLIILTTWLLPLMMLASQNHMKKENMMHQKLYISMLISL QILLIMTFSATELILFYILFEATLIPTLIIITRWGNQTERLNAGIYFLFYTLIGSIPL LIALISIQNSMGTLNFLILSLTTHPLPSTWSNTILWLACMMAFMIKMPLYGVHLWLPK AHVEAPIAGSMILAAILLKLGGYGMMRVSIILDPLTKSLAYPFIILSLWGMIMTSSIC LRQTDLKSLIAYSSVSHMALVITAIMIQTPWSFMGATMLMIAHGLTSSLLFCLANTNY ERIHSRTMIMARGLQMIFPLMATWWLLASLANLALPPLINLMGELFIVMATFSWSNPS IILMATNIVITGMYSMYMIITTQRGKLTSHMNNLQPSHTRELTLMALHIIPLMLLTIN PKLITGLTM" tRNA 11523..11590 /product="tRNA-His" tRNA 11591..11650 /product="tRNA-Ser" /codon_recognized="AGY" tRNA 11650..11720 /product="tRNA-Leu" /codon_recognized="CUN" gene 11721..13553 /gene="ND5" /db_xref="GeneID:7066257" CDS 11721..13553 /gene="ND5" /codon_start=1 /transl_table=2 /product="NADH dehydrogenase subunit 5" /protein_id="AP_004902.1" /db_xref="GI:110189673" /db_xref="GOA:P11661" /db_xref="InterPro:IPR001516" /db_xref="InterPro:IPR001750" /db_xref="InterPro:IPR003916" /db_xref="InterPro:IPR003945" /db_xref="InterPro:IPR010934" /db_xref="UniProtKB/Swiss-Prot:P11661" /db_xref="GeneID:7066257" /translation="MNMMTILILMILDLLTTPITFSMTILTKLMYFRHMLITSIKFSF LLSLLPLLLFFHHNTEYMITNWHWLTINSIKLTMSFKIDYFSILFLSVSLFVTWSIMQ FSSWYMHSDPHINRFIKYLMMFLNNMLILTSANNLFQLFIGWEGVGIMSFLLIGWWYG LADANTAALQAILYNRVGDIGFILAMTWFCLNMNSWELQQIFLTNTNNNLVPLTGLLI AATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLMIRFHPLTSNNSTIMTA MLCLGAITTLFTAICALTQNDIKKIVAFSTSSQLGLMMVTLGINQPYLAFLHICTHAF FKAMLFMCSGSIIHILNDEQDIRKMGNMMKAMPFTSSCLIIGSLALTGMPFLTGFYSK DLIIEAINTCNTNAWALMITLIATSMTAVYSMRIIYFVTMTKPRYSPLITINENNPNL INPIKRLALGSILAGFLISLNIPPTNIQILTMPWHLKMTALLITILGFAIALELNNLT LNLSMSKPTKLSSFSTSLGYYPPIMPRIIPQKTLNSSYKLSLNLLDLIWSEKTIPKST SITQTQLSKMMSNQKGLIKLYFLSFLITISLIFILHTLNPEWFQ" gene complement(13531..14049) /gene="ND6" /db_xref="GeneID:7066258" CDS complement(13531..14049) /gene="ND6" /codon_start=1 /transl_table=2 /product="NADH dehydrogenase subunit 6" /protein_id="AP_004903.1" /db_xref="GI:110189674" /db_xref="GOA:P03926" /db_xref="InterPro:IPR001457" /db_xref="UniProtKB/Swiss-Prot:P03926" /db_xref="GeneID:7066258" /translation="MTNYMFILSLLFLTGCLGLALKPSPIYGGFGLIVSGCIGCLMVL GFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWGSNWFIFSFFVLGLFMELVV FYLFSLNNKVELVDFDSLGDWLMYEIDDVGVMLEGGIGVAAIYSCATWMMVVAGWSLF AGIFIIIEITRD" tRNA complement(14050..14118) /product="tRNA-Glu" gene 14124..15266 /gene="CYTB" /db_xref="GeneID:7066259" CDS 14124..15266 /gene="CYTB" /codon_start=1 /transl_table=2 /product="cytochrome b" /protein_id="AP_004904.1" /db_xref="GI:110189675" /db_xref="GOA:P00159" /db_xref="UniProtKB/Swiss-Prot:P00159" /db_xref="GeneID:7066259" /translation="MTNIRKSHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQ ILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLQANGASMFFICLFLHVGRGL YYGSYTFLETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTL VEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKI PFHPYYTIKDLLGVFMLLLFLMTLVLFFPDLLGDPDNYTPANPLNTPPHIKPEWYFLF AYAILRSIPNKLGGVVALILSILILAFLPFLHTSKQRSLTFRPITQILYWILVANLLV LTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIVEDKMLKWN" tRNA 15268..15334 /product="tRNA-Thr" tRNA complement(15336..15403) /product="tRNA-Pro" D-loop 15404..16300 STS 15765..16119 /standard_name="PMC139749P2" /db_xref="UniSTS:270889" ORIGIN 1 gttaatgtag cttataataa agcaaagcac tgaaaatgct tagatggatt caaaaatccc 61 ataaacacaa aggtttggtc ctggccttat aattaattgg aggtaagatt acacatgcaa 121 acatccataa accggtgtaa aatcccttaa agatttgcct aaaacttaag gagagggcat 181 caagcacata atatagctca agacgccttg cctagccaca cccccacggg actcagcagt 241 gataaatatt aagcaatgaa cgaaagtttg actaagctag tacctctcag ggttggtaaa 301 tttcgtgcca gccaccgcgg tcatacgatt aacccaaact aattattttc ggcgtaaaac 361 gtgccaacta taaatctcat aatagaatta aaatccaact tatatgtgaa aattcattgt 421 taggacctaa gcccaataac gaaagtaatt ctaatcattt atataatgca cgatagctaa 481 gacccaaact gggattagat accccactat gcttagccct aaaccttaat aattaaacct 541 acaaaattat ttgccagaga actactagct acagcttaaa actcaaagga cttggcggta 601 ctttatatcc atctagagga gcctgttcta taatcgataa accccgttct accttacccc 661 ttctcgctaa ttcagcctat ataccgccat cttcagcaaa ccctaaaaag gcactaaagt 721 aagcacaaga acaaacataa aaacgttagg tcaaggtgta gccaatgaag cggaaagaaa 781 tgggctacat tttcttttcc cagagaacat tacgaaacct ttatgaaact aaaggacaaa 841 ggaggattta gtagtaaatt aagaatagag agcttaattg aatagagcaa tgaagtacgc 901 acacaccgcc cgtcaccctc ctcaaattag attgacattc acatatacat aatttcacta 961 acaaatttat gagaggagat aagtcgtaac aaggtaagca tactggaaag tgtgcttgga 1021 ataatcacag tgtagcttaa tcacaaagca tctggcctac acccagaaga attcataaaa 1081 aatgaacact ttgaactaac cctagcccta caaccaacca acataactaa acccccacat 1141 aaactaaaac atttaactca aaaagtattg gagaaagaaa tttacttacc aagagctata 1201 gagaaagtac cgcaagggaa atgatgaaag actaatttaa agtaaaaaca agacaaagat 1261 taaacctgta ccttttgcat aatgaattaa ctagaaaatc cttaacaaaa agaatttaag 1321 ctaagaaccc cgaaaccaaa cgagctacct aaaaacaatt tcatgaatca acccgtctat 1381 gtagcaaaat agtgggaaga tttttaggta gaggtgaaaa gcctatcgag cttggtgata 1441 gctggttgcc caaaaaagaa tttcagttca aactttaagc ttccatcaga acaacaaatc 1501 aaaatgtaaa cttaaaatat agccaaaaga gggacagctc tttaggaaac ggaaaaaacc 1561 ttaaatagtg aataaacaac tacaatcact taaccattgt aggcttaaaa gcaagccatc 1621 aataaagaaa gcgtcaagcc acatcatctt acacacacac taattccaca aacctcaaaa 1681 attccaaaat tacaaattgg gctaaatcta tgatcctagt gaatactgtt aatatgtgaa 1741 caagaaccaa tccaccaagc acaagtgcta agacaaccgg ataaccattg ttaattattg 1801 aatcataggc ataacccaac aatagaatta cctatcccta actcgttagc ccaacacagg 1861 cgtgctttaa ggaaagttta aaaaagtaaa ggaactcggc aaacacgaac cccgcctgtt 1921 taccaaaaac atctcctcta gcataacaag tattagtggc atcgcctgcc cagtgactaa 1981 agttccacgg ccgcggtatc ccgaccgtgc aaaggtagga taatcacttg ttccttaatt 2041 agggactaga atgaatggct aaacgagggt ccaaccgtct cttacttgca atcagtgaaa 2101 ttgaccttcc agtgaagggg cggactcata ataaaagacg agaagaccct atggagcttt 2161 aatttactaa tttcaattta tataaaaaaa cctaatgggc gaaaacaaca aaattatgaa 2221 ctaccaaatt tcggttgggg tgacctcgga gaataaaaaa tcctccgaat gattataacc 2281 gagtcggtaa ccgtgtccga cccagtcaag taatactaat atcttattga cccaattatt 2341 gatcaacgga ccaagttacc ctagggtaac agcgcgacct atttaagagt tcatatcgac 2401 aattagggtt tacgacctcg atgttggatc aggacatccc aatggtgcag aagctattaa 2461 tggttcgttt gttcaacgat taaagtccta cgtgatctaa gtccggcaat ccaggtcggt 2521 ttctatctat ttacaatttc tcccagttac gaaaggacaa gagaaatgga gaccaaccaa 2581 tcctaggctt ccaaccaatt tagaaaaact taataaagta tatatgtaca ataaataacc 2641 ttagacccaa gttattaggg tggcagagcc aagtaattgc gtaagactta aaaccttgtt 2701 cccagaggtt caaatcctct ccctaatagt gtactttatt aatatcctaa cactcctaat 2761 cccaatctta attgccatag gccttctcac cctagtagaa cggaaaatcc taggctacat 2821 acaattacgc aaaggcccca acaacgaagg cccatatggt aaactacaac catttgcaga 2881 tgccataaaa ctattcataa aagaacccat acgccctcta accacctcaa tatcactatt 2941 tattatcgcc ccaaccctct cccttacact agctctaagc ctatgaattc ccttaccaat 3001 accccacccc cttatcaacc tcaacctagg cataccattt attctagcca catccagcct 3061 ttcggtctac tccattctat gatcgggatg agcctcaaat tcaaaatact ccctattcgg 3121 agccctacga gccgttgccc aaaccatctc ttacgaagtc acaatagcct tatacctctt 3181 atccgtcctc ctaataagcg gctccttctc cctacaaata cttatcacta cacaagaaca 3241 tatctgacta ttaatccccg cctgaccaat agccataata tgatacattt caaccctcgc 3301 agaaacaaat cgagctccct tcgacttaac agaaggagaa tcagaattag tctcaggctt 3361 taacgtcgaa tacgccgcag gaccattcgc cctattcttc atagccgagt acaccaacat 3421 tattctaata aacgccctaa catcaattgt attcctaggc cccttatatc atatcaatta 3481 ccctgaatta tactcaacca gcttcataac agaaacacta cttctatcca caactttcct 3541 atggattcga gcatcctacc cccgttttcg atatgaccaa ctaatgcacc tcctatgaaa 3601 aaatttcctc ccactaacac tagcattctg catatgatac atttccctgc caattttcct 3661 agcaggaatt ccaccctaca catagaaata tgtctgacaa aagagttact ttgatagagt 3721 aaataataga ggtttaaatc ctcttatttc taggacaata ggaattgaac ctacacctaa 3781 gaattcaaaa ttctccgtgc caccaataca ccctatccta catagtaagg tcagctaact 3841 aagctatcgg gcccataccc cgaaaatgtt ggttaaaccc ttcccgtact aataaatcca 3901 attaccctaa ccattattta cttaaccacc tttaaaggcc gcctaatcac gacacttagc 3961 accaacttac caccaatatg agtaggattg gaaataagcc ttttagctat catcccactt 4021 ctagccaaca aaaaaagccc acgatcaact gaagcagcaa caaaatattt tctaacccaa 4081 gctacagcct caataattat cctactagtc atcatcctca actacaaaca atcaggaata 4141 tgaacccttc aacaacaaac caataacata ctactcaaca taatactcat ttcactggcc 4201 ataaaacttg gactagcccc attccactac tgactacccg aagtcaccca aggaattccc 4261 ctacacattg gattaatctt actaacatga caaaaaattg ctccactatc aattctatac 4321 caattttatc aactcctaaa cccaactatc accaccattc tcgcaatttc atcagtcttt 4381 gttggcgcct gaggaggact taaccagacc caaacacgaa aaatcatagc atactcatca 4441 attgcccaca taggatgaat aacagcaatc cttccataca accctaactt aaccctccta 4501 aacttaacaa tttacatcct acttactgtt ccaatattca attacatcat aacaaactca 4561 gcaacaacaa tcaacacact ctcactcgca tgaaataaaa ctcccataat cctaaccata 4621 gcatccatca tcctcctatc actaggagga ctcccccctc tcacaggatt tttaccaaaa 4681 tgagcaatta tctccgagct tctaaaaaac aactgctcaa ccctatcaac actaatagct 4741 atcatagccc tattaagcct attcttctat actcgactaa tttactctat atccctcacc 4801 acattcccaa ccaacaacaa ctccaaaata atctcccacc accaaaaccc aaaacataat 4861 tttatcctcc caaccctcac agtattaagt accctaaccc taccgctttc ctcccaacta 4921 atcacataga agtttaggat atacagttca agagccttca aagcccttag aaaacaaaca 4981 agtttaactt ctgataagga ctgtaagact atatcttaca tctgttaaat gcaaatcaac 5041 tgctttaatt aagctaaatc ctcaactaga ttggaaggaa tcaaattcct acgaaaattt 5101 agttaacagc taaataccct acttactggc ttcaatctac ttctcccgcc tatcagaaaa 5161 gaggcgggag aagccttagt agaggagatt ctctacacct tcgaacttgc aattcgacat 5221 gataatcacc ttaaggcttt ttggtaaaaa gggggctcaa cccctgtctt tagatttaca 5281 gtctaatgct tactcagcca ttttacctat gttcgtaaac cgttgactct tttcaactaa 5341 ccacaaagat atcggaaccc tctacctatt atttggagcc tgagcaggaa tagtagggac 5401 agctttgagt attctaattc gagctgaact aggacagcca ggcgcactcc taggagatga 5461 ccaaatctat aatgtcatcg tcacagccca tgcattcgta ataattttct ttatagtaat 5521 acctataata attggaggct tcggaaactg acttgtacca ctaataattg gagcccctga 5581 tatagcattc ccacgaataa ataacataag cttttgactg cttcctccat catttctact 5641 ccttttagca tcctccatag tagaagctgg agctggaaca ggatgaacag tatatccccc 5701 cttagccgga aacctagccc atgctggggt atccgtagat ttaactattt tttccctcca 5761 cctagccggg gtgtcttcta tcttaggagc tatcaacttt atcaccacta tcattaatat 5821 aaaaccccct gctataaccc aatatcagac acctctcttt gtatgatccg tactaattac 5881 agccgtccta ctacttctct cactgccagt attagcagca ggtatcacta tactccttac 5941 agaccgaaat ctaaatacta ctttcttcga ccccgctgga ggtggagacc caattcttta 6001 tcaacaccta ttctgattct tcggccaccc agaagtgtac atcttaattc ttccagggtt 6061 tggaattatt tcacatgtag ttacctatta ctctggaaaa aaagaaccct tcggatatat 6121 aggtatggta tgaaccataa tatctattgg cttcctagga tttattgtat gagcacatca 6181 catattcaca gtaggcctag atgtagacac ccgagcctac tttacatctg ccactataat 6241 tatcgcaatt cctacaggcg taaaagtatt cagctgactc gctacactac atggaggaaa 6301 tatcaaatga tcccccgcca tattatgagc cttagggttt atcttcttat tcacagtagg 6361 gggcctaaca gggatcgtac tatctaactc atcccttgac attgtacttc atgatacata 6421 ctacgtagta gctcacttcc actatgtctt atctatagga gcagtattcg ccatcatagc 6481 tggcttcgtc cactgattcc cactattctc aggctatacc ctaaatgaca catgagcaaa 6541 agcccacttt gccattatat ttgtaggtgt aaacataaca ttttttcctc aacacttcct 6601 aggattagca gggatacctc gtcgttactc tgattatcca gatgcttata ccacatgaaa 6661 tacagtctcc tctataggct cattcatctc acttacggcc gtccttgtaa tgatcttcat 6721 gatttgagaa gccttcgcat caaaacgaga agtgctctca atttcctact cttcaactaa 6781 cctagaatga ctgcatggat gccccccacc ttaccacaca ttcgaagaac cttcctatgt 6841 aaaagttaaa taagaaagga aggaatcgac cccctacaac tggtttcaag ccaatttcat 6901 aaccattatg tctttctcaa tgagatatta gtaaaataat tacataacct tgtcaaggtt 6961 aagttataga cctaatccta tatatcttac atggcttacc catttcaact tggcttacaa 7021 gacgctacat cacctatcat agaagaactt acaaactttc atgaccacac cctaataatt 7081 gtattcctca tcagctccct agtactttat attatttcac taatactaac aacaaaacta 7141 acacacacaa gcacaataga cgcccaagaa gtagaaacaa tttgaacaat tctcccagct 7201 gtcattctta ttctaattgc ccttccctcc ctacgaattc tatacataat agacgagatt 7261 aataacccag ttctaacagt aaaaactata ggacaccaat gatactgaag ctatgaatat 7321 actgactatg aagacctatg ctttgactcc tacataatcc caaccaatga cctaaaacca 7381 ggtgaacttc gtctattaga agttgataat cgggtagtct taccaataga acttccaatt 7441 cgtatactaa tctcatccga agacgtcctg cactcatgag ccatcccttc actagggtta 7501 aaaaccgacg caatccccgg ccgcctaaac caagctacag tcacatcaaa ccgaccaggt 7561 ctattctatg gccaatgctc tgaaatttgc ggctcaaatc acagcttcat acccattgta 7621 ctagaaatag tgcctctaaa atatttcgaa aactgatcag cttctataat ttaaactcat 7681 tgcgaagctt agagcgttaa ccttttaagt taaagttaga gacaacaaat ctccacaatg 7741 acatgccaca actagacaca tccacatgat ttattacaat catctcctca atagccacac 7801 tatttatttt atttcaatta aaaatttctt cccaaacctt tcctgcacct ccctcaccca 7861 aaactatagc cacagaaaaa acgaataacc cttgagaatc aaaatgaacg aaaatctatt 7921 tgcctctttc attaccccca caataatagg tctaccaatt gttgtgacca ttattatgtt 7981 cccatcaatt ctattcccat catcagaacg cctaatcagc aaccgactac actcatttca 8041 acactgacta atcaaactta tcatcaaaca aataatgtta attcacacac caaaaggacg 8101 aacctgagcc ctaataattg tatccctaat tatatttatt ggctcaacca accttctagg 8161 gcttcttccc catacattta cccctaccac tcagctatct atagacctaa gcatagccat 8221 ccccctatga gcaggagccg taattctagg tttccgacac aaactaaaaa attctttagc 8281 ccacttctca ccgcaaggaa cccccatctc actaattccc atactaatca tcatcgaaac 8341 tatcagccta tttattcaac cgatagcact agcagtacga ctaacagcaa acattacagc 8401 aggccatcta ttaatgcatc taatcggagg agctacccta gtacttatag acatcagccc 8461 accaaccgct acaattacat ttattattct acttctactt acagtacttg aatttgccgt 8521 agccttaatt caagcctatg tattcaccct tctagtcagc ctgtacctac atgataacac 8581 ataatgaccc accaaaccca tgcataccat atagtaaacc caagcccatg accactaaca 8641 ggagccctat cagctcttct actcacatcc ggcttagtaa tatgattcca ttacaactcc 8701 acaattctcc tatcattagg cctcctgaca aacatcctaa ctatatatca atgatgacga 8761 gatatcatcc gtgaaggaac ataccaaggc caccacaccc ctattgtaca aaaaggcctc 8821 cgatacggaa taatcctgtt tattgtctcc gaagtattct tctttgccgg atttttctga 8881 gcattttatc attccagcct agttcctacc cacgacctag gcggttgctg acccccaaca 8941 ggaatcaccc ctttaaatcc cctagaagta ccccttctaa atacatcagt cctcttagca 9001 tcaggagtct caattacatg agcccatcac agcctaatag aaggcaaccg aaaccatata 9061 aaccaagccc tactaatcac cattctctta ggattatatt tcactatctt acaagcctca 9121 gagtatttcg aaacatcatt ttctatctca gacggaattt acggctcaac attcttcata 9181 gcaacgggat ttcatggcct ccacgtaatt attggctcaa ctttcctaat tgtctgtcta 9241 ctacgacaac taaaattcca cttcacatca aaacatcatt tcggatttga agccgcagca 9301 tgatactgac acttcgtaga tgtagtttga ctattcctat acgtttctat ctattgatga 9361 ggatcctact cccttagtat aaacaataca actgacttcc aatcagttaa ttctgaaaaa 9421 actcagaaga gagtaattaa cctacccatt atcatcacaa ttaacatcac cttatccttt 9481 atcctcattt caattgcatt ctgattgcct caaataaact tatactccga aaaagcaaac 9541 ccatatgaat gtggcttcga cccaacaagt tctgcacgcc ttcctttttc aataaaattt 9601 ttcttagtag ccattacatt tctactattc gacctagaaa tcgccttact acttcccctc 9661 ccatgagcga ttcaaacaac caataccact acaataatag caactgcctt tattttagtc 9721 actattttgt ctcttggcct agcctacgaa tgaacacaaa aaggactaga atgaacagaa 9781 taattggtaa ttagtttaaa taaaattaat gatttcgact cattagatta tgataataat 9841 cataattacc aacaatgaca tctgctttcc taaatttaac tatagccttt acattatctc 9901 tactaggtac ttttatattt cgctcccacc taatatccac tctcctctgc ctagaaggaa 9961 taatactatc actatttgtc ataacttcaa catccacatt aaactccaac tccataatct 10021 ccataaccat cccaattacc attctagttt ttgcagcctg cgaagcagca gtaggtttag 10081 ccttactagt aaaaatttca aatacttacg gaacagacta cgtacaaaac ctcaaccttc 10141 tacaatgtta aaaattattt tcccatctat catactcctc ccactaacat gactctcagc 10201 caacaaaaaa atctgaacca atgtcacctc ctacagcttt ctagtgagcc tattaagctt 10261 atcactccta tgacaaaatg acgaaaatta cctaaatttc tcagttatat tctcctccga 10321 tccattatcc accccactaa tcattctaac aacttgactc ctcccactaa taatgctcgc 10381 tagccaaaat cacataaaaa aagaaaatat aatgcatcaa aaactttaca tctcaatact 10441 tattagcctc caaattttac tcatcataac attctccgca acagaactaa ttttatttta 10501 tatcctgttc gaggccactc taatcccaac actaattatc attacacgat gaggcaacca 10561 aacagaacgc ttaaatgcag gaatttattt cctgttttat acactaattg gctccatccc 10621 actcttaatt gccctcattt caatccaaaa ctcaatagga acactcaact tcctaatcct 10681 ttccctcaca acacaccccc taccctcaac atgatccaac accattctat gactagcatg 10741 tataatagca tttataatca aaataccatt atacggagtc catctatgat taccaaaagc 10801 ccacgtagaa gctccaattg caggctctat aattttagca gcaattctcc taaagctagg 10861 gggttatggg ataatacgag tttccatcat tctagacccc ctaacaaaat ctttagccta 10921 cccattcatc atcctctcat tatgaggcat aattataact agctcaatct gcctacgcca 10981 aacagatcta aaatcattaa ttgcttactc atcagtaagc catatagccc tagtcatcac 11041 agccattata atccagacac catgaagctt catgggagcc acaatactaa taatcgccca 11101 cggcttaacc tcatcactct tattctgcct agcaaacacc aactacgaac gaattcacag 11161 ccgaactata attatagctc gaggattaca aataatcttt ccattgatag caacatgatg 11221 actattagca agcttagcca acctagcact accaccccta attaacctca taggcgagtt 11281 attcattgtt atagcaacat tttcctgatc gaacccctct atcatcctta tagcaactaa 11341 cattgtcatc acaggaatat actcaatata tatgattatc acaacccaac gaggaaaact 11401 aaccagccac ataaacaacc tccaaccttc ccacacacga gaattaacac tcatagctct 11461 acacattatt cccctcatac tattaacaat caaccctaaa ctcatcacag gcctaacaat 11521 atgtagatat agtttacaaa aaacattaga ctgtgaatct aacaacagga aatcaaattc 11581 cttatttacc aagaaagtat gcaagaactg ctaattcatg cacccatacc taaaacatat 11641 ggctttctta cttttatagg atagaagtaa tccattggtc ttaggaacca aaaaccttgg 11701 tgcaactcca aataaaagta ataaatataa taacaatcct aatcctcata attcttgatt 11761 tacttacaac accaatcaca ttttcaataa caatcttaac caaacttatg tacttccgtc 11821 atatgctcat tacatcaatt aaattctcat tcctccttag cctcttacct ttactactat 11881 tcttccacca caacacagaa tacataatta ctaactgaca ttgactaact attaattcta 11941 ttaaacttac tataagtttc aaaattgact atttctcaat cctattccta tcagtatccc 12001 tattcgtaac atgatcaatt atacaattct cttcatgata tatacactct gacccccaca 12061 ttaaccgatt cattaagtac ttaataatat tcctgaataa catactaatc ctaacctcag 12121 ctaacaatct attccaactc tttattggat gagaaggggt aggaattata tccttcttat 12181 taatcggatg atgatatggc cttgcagacg ccaacacagc ggccctccaa gcaatcctct 12241 acaaccgagt cggagacatt ggtttcatcc tagctataac ctgattctgc ctaaacataa 12301 actcctgaga actccaacaa attttcttaa ccaacaccaa caacaatcta gtccctctca 12361 caggactact aattgcagcc acaggaaaat ccgcccaatt cggacttcat ccatgactcc 12421 catcagctat agaaggccca actcccgtct ctgccctact acactcaagc acaatagttg 12481 tagcagggat cttcctaata atccgattcc accccctaac ctcaaacaat agtactatta 12541 taacagccat actatgtctt ggtgcaatca ccacattatt cacagcaatc tgtgctctca 12601 cccaaaacga catcaaaaaa atcgtagctt tctcaacatc cagccaacta ggccttataa 12661 tagtcacatt agggattaac caaccctacc ttgctttcct ccacatttgc acccatgcat 12721 tcttcaaagc catattattc atatgctccg gatcaatcat ccatatcctc aacgatgaac 12781 aagacattcg aaaaataggc aatataataa aagcaatacc attcacatca tcttgtctca 12841 ttatcggaag cctagccctt accggaatac ctttcctcac aggattctat tcaaaagatc 12901 tcatcatcga agccatcaac acgtgtaaca ccaacgcctg agccctaata atcactttaa 12961 tcgccacatc cataactgct gtgtacagca tacggatcat ctacttcgtc accatgacaa 13021 aaccacgata ctccccacta attactatta atgaaaacaa cccaaacctc attaatccaa 13081 tcaaacgcct agcattagga agcatcctag caggcttcct tatctcacta aatattcctc 13141 caactaacat tcaaattctc acaataccct gacatttaaa aataacagcc ctacttatta 13201 caatcctagg atttgccatt gccctagaac ttaacaattt aacactaaat ctatcaataa 13261 gcaaacccac caaactatca tcattctcaa cctccctagg ctactaccca ccaattatac 13321 cccgaattat tcctcaaaaa actctaaatt ctagctacaa attatcctta aacctactag 13381 acctaatctg atcagaaaag acaatcccaa aatcaacctc aatcacccaa acccaactat 13441 ctaaaataat atccaaccaa aaaggactaa tcaaactata tttcctatca tttctcatca 13501 ctatttcact aatttttatc ttacacacac ttaatcccga gtgatttcaa taataataaa 13561 aatccccgca aacaatgacc acccagccac cactatcatt caagtagcac aactataaat 13621 agccgcaacc ccaatccccc cctccaacat aaccccaaca tcatcaatct catacattaa 13681 tcaatcgcct agactatcaa aatcaactaa ctccacctta ttattcaaac taaacaagta 13741 gaacactacc aactccataa aaagccctaa aacaaaaaaa ctaaaaataa accaattaga 13801 ccctcaagtt tccggatatt cctcagtagc catagcagtt gtatacccaa atacaaccaa 13861 catcccaccc aaataaatta aaaatactat taaacctaaa aacgaacccc caaaccctaa 13921 aactattaag cacccaatac atccactaac aatcaatcca aacccaccat aaataggtga 13981 aggcttcaac gccaacccta gacaaccagt caaaaacagt aaacttaaaa taaacatata 14041 atttgtcatt atttctacac agcatttaac tgtgactaat gacatgaaaa atcatcgttg 14101 taattcaact atagaaacat ctaatgacaa acatccgaaa atctcacccc ctattcaaaa 14161 tcatcaacca ctcctttatc gacctaccgg ccccatctaa catctcatca tgatgaaact 14221 tcggttctct actaggagta tgcctcatag tacaaatcct cacaggctta ttcctagcaa 14281 tacactacac gtctgatacc ataacagcat tctcatcagt cacccacatc tgccgagacg 14341 taaactacgg ctgactaatc cgatacctac aagccaacgg cgcctcaata tttttcatct 14401 gcctattcct ccatgtggga cgaggactat actatggatc ctacactttc ctagaaacct 14461 gaaacattgg gatcatccta ctatttgcag tcatagcaac tgcattcatg ggctatgtac 14521 tcccatgagg acaaatatca ttctgaggag ctacagtaat tacaaaccta ttatcagcta 14581 tcccttacat tgggactacc ctagtcgaat gaatctgagg aggcttctca gtagacaaag 14641 caaccctaac acgcttcttc gcattccact tcatcctccc attcattatc gccgcccttg 14701 caattgtaca tcttcttttc ctccacgaaa caggatcaaa taaccccaca ggattaaact 14761 ccgacgcaga caaaatccca ttccatccat attatacaat taaagacctc ctaggtgtat 14821 ttatattact attattccta ataaccctag tactattctt cccagaccta ctaggagacc 14881 cagacaatta tacacccgct aaccccctca acaccccacc ccacatcaaa ccagaatgat 14941 actttctctt tgcctacgct attctacgct ccattcccaa caaactagga ggggtcgtag 15001 ccctaatctt atcaatccta atcttagcct tcctaccatt cctgcatacc tcaaaacaac 15061 gcagcttaac attccgccca atcacccaaa tcctttactg aatcctagta gccaacctcc 15121 tagtcttaac atgaatcgga ggccaaccag tagaacaccc atttatcatt attggtcaac 15181 tagcctccat cagttatttt tcaattatcc tcattctcat accaatctct ggaattgttg 15241 aagacaaaat gttaaaatga aattaatgtc ccgatagtat aaaaattact ctggtcttgt 15301 aaaccaaaaa tgaagagtca gtcttctcag gacaatcaag aagaaggaac tacctcccca 15361 ccatcaacac ccaaagctga tattctactt aaactacttc ttgtcagtac ataaaatgat 15421 atggacatta aaacatttat gtatatcgta cattaaatta ttttccccaa gcatataagc 15481 atgtaatata tatctaatga tttaggacat acatttaaac tcaactataa attcacaaca 15541 acatgtctat tctcaaatac attaagataa tgcttattag acatatctgt gttattagac 15601 atgcaccatt aagtcataaa cctttctctt ccatatgact atccctgtcc ccaattggtc 15661 tctatttcta ccatcctccg tgaaatcaac aacccgccca ctcgtccccc tcttctcgct 15721 ccgggcccat tcgtcctggg ggtgactata ctgaaacttt accaggcatc tggttcttac 15781 ttcagggcca tcaattggtt catcgtccat acgttcccct taaataagac atctcgatgg 15841 taacgggtct aatcagccca tgatcaacat aactgtggtg atatacattt ggtatttttt 15901 aattttcgga tgccttcctc aacatagccg tcaaggcatg aaggtcagca caaagtcctg 15961 tggaaccttt tagttaaggg tcatttatcc tcatagacaa agctcgaaag actattttat 16021 tcatgtttgt aagacataaa tatttataaa tactgaaaaa tctgtcaaca aaccccccca 16081 ccccctacac ctgaaacttc aatgccaaac cccaaaaaca ttaaagcaag aattaaataa 16141 aacaaaaagc tacttaattc ttaaaaggct tctccattct agtagaccac aaaattttaa 16201 cttaaatctt agcattggta aaatttcccg acacaaaatc tttcctccta actaaaccct 16261 ctttacttgc ctaccctcag aaaattccac atacaccaaa // |
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