Dbfetch
LOCUS NM_206631 8828 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster small conductance calcium-activated potassium channel (SK), transcript variant M, mRNA. ACCESSION NM_206631 VERSION NM_206631.4 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 8828) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 8828) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 8828) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 8828) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 8828) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 8828) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 8828) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 8828) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 8828) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 8828) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 8828) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 8828) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 8828) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 8828) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 8828) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 8828) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 8828) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 8828) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 8828) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 8828) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 8828) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 8828) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 8828) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_206631.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..8828 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..8828 /gene="SK" /locus_tag="Dmel_CG10706" /gene_synonym="BcDNA:GM01744; CG10706; CG12733; CG4179; Dmel\CG10706; dSK; Sk" /note="small conductance calcium-activated potassium channel" /map="4F5-4F9" /db_xref="FLYBASE:FBgn0029761" /db_xref="GeneID:31456" CDS 604..3387 /gene="SK" /locus_tag="Dmel_CG10706" /gene_synonym="BcDNA:GM01744; CG10706; CG12733; CG4179; Dmel\CG10706; dSK; Sk" /note="CG10706 gene product from transcript CG10706-RM; CG10706-PM; SK-PM" /codon_start=1 /product="small conductance calcium-activated potassium channel, isoform M" /protein_id="NP_996354.2" /db_xref="FLYBASE:FBpp0291165" /db_xref="GeneID:31456" /db_xref="FLYBASE:FBgn0029761" /translation="MSIQKLNDTTNSGYVSSEETDSLLVSSSNPSKGGGRTALLRQVK SNSTNGPTTGASTSSSGSVSGGGGGSGSGGGSASGSAAGASKPTLMRQDRTSTYLTSP QQSQHARMGSEESMRGGASGAAGHDEDVEQGLVRSSIVPDIEVHEEDQEQHSQQLNAT TMATMTNNQQQQQPTISIMNLSLKPGDSHSHSSSPGSHPNLGTSSYQNLASSIPPSVP SRCRACRNCSRRASTTPTTLIDRSASRDSVKSAFQQGNLSGSMAICISNSALPQQQQL QQQYHLQQQQQQHYQLQQHHLHQQQLQQSQQQVPPVLITSSPTNGSRIIRQSSQPESS STAICCGPHSACVGHAHSHSHTVPNVSLKQLRESSGDGIAGIAADSLRINGGMRPFKQ LRKPASTLSIPGSMKTPSIANREQISSGCNEEAAEALVGIHSDYPRYEMYMEERALTG GNTSRKPSTNSAKHKPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSS AGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRI SQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICR VMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTL RQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALL VAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGR VRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQNTVYEIISDMSSRQDAIEE RLTNLEDKMQSIQEHMESLPDLLSRCLTQHQERIEQRRNFLHPDTAAVAPIQAPTPQS MFNAAPMLFPHSS" ORIGIN 1 tcagtatcgc acaaacaaca ctaacggaaa catcaacgtg aaagcgagac ggacgccctc 61 cgtcccgtta tatgctgtgt ctgtctttaa tatatatata gttaaacaaa ataaaaatat 121 caaataaaaa acaagtgcaa gcaaagagaa aagcgcccaa tgcggccaat ggaaatgcca 181 aagaaaatgc agcagctaca aattcgacaa caaatgcaaa tgcgacagca acagcagaag 241 aagcagcagc agcaacaaca tcaactgcaa tttctcaaca cataagtcca ccgaattttc 301 cgtctttgtc gcgcgcgctc acacatatac aagcacacac atccatacac ggagacacat 361 gcatgtgcat aaatggcaat atggacgaac agcagcagca tttgcgttgt ataccaacac 421 agtgacacgc gcgtgccaaa tattgccgat tttatcacac gaacaacaac aacagcaaca 481 acaacaccag cgggaccagc tattaactaa aggagccatt acaacaacaa taacaagatc 541 cagcaaagca acaacaacaa cgaaagcaac gaacattgct ggaaggcgtc gcaaaatatc 601 aaaatgtcaa ttcagaagct taacgacacc acaaactcgg gctacgtgag ttccgaggag 661 acggactcgc tgctggtgag cagctcgaat ccgtcgaagg gcggcggtcg gacggctctg 721 ctccgccagg tgaagagtaa ctcgacaaat gggccaacga cgggggcgtc cacatcgtcc 781 tcgggatcgg tatcgggcgg cggtggtgga tccggttccg gtggcggatc agcatcgggc 841 tcagcagctg gggcttccaa gccaacgcta atgcgtcagg atcgaacatc cacctacctg 901 acaagtccgc agcagtcgca gcacgcgaga atgggttccg aggagagcat gcgaggtgga 961 gccagcggag ctgccggaca cgacgaggat gtggaacagg gcctggtccg tagcagcata 1021 gtgcctgata tcgaagtaca cgaagaggac caagagcaac acagccagca gttaaatgca 1081 acgacgatgg caacgatgac caataaccaa cagcaacagc aaccgaccat atcaattatg 1141 aatttaagcc tcaagccagg cgatagccat agccatagct ccagtccggg tagtcatccc 1201 aatttgggca cctcatcata tcagaatctg gcatcgagca taccgcccag cgtaccgagt 1261 cgctgcaggg cgtgccgcaa ttgcagtcga cgtgcttcca ccacgcccac cacgctgatc 1321 gatcgctccg cctcccgcga cagtgtgaaa agtgccttcc agcagggcaa tcttagcggc 1381 tccatggcca tttgcatatc gaactcggcc ctgccgcagc agcagcagtt gcagcaacag 1441 tatcacctgc aacagcaaca gcagcagcac tatcagttgc agcaacacca tctgcatcag 1501 cagcaactgc agcagtcgca gcagcaggtg ccgccggtgc taatcacatc atcgccaacg 1561 aatggatcac ggataatacg gcaaagttca cagccggaat cgagcagcac ggccatttgt 1621 tgtggtcccc attccgcttg cgttggccac gcccactcgc actcgcacac ggtaccgaat 1681 gtttcgctga agcagctgcg cgagagttcc ggcgatggaa tcgcgggcat tgcagccgac 1741 tctctgcgga tcaacggtgg catgcggccc ttcaagcagc tccgcaaacc ggcgtcgaca 1801 ctctcaattc ctggctcgat gaaaacacct tccattgcga accgggaaca gatctcatct 1861 ggatgcaacg aagaagcggc cgaggcacta gtgggtatcc actcagacta ccctaggtat 1921 gaaatgtata tggaagaacg tgctcttact ggcggcaata cgtccaggaa gccatcaaca 1981 aactcggcca aacacaaacc caatgtgggc tatcgcctgg gaaagaggaa agccctcttc 2041 gagaagcgca aacggatcag cgattacgcc ctggtcatgg gcatgttcgg gatcatcgtg 2101 atggttatcg aaaacgaact gagcagtgcc ggtgtctaca caaaggcatc gttctactcg 2161 acagcgttaa aaaccttaat atctgtttcg actgtgattc ttttaggact tatagtagct 2221 taccatgctt tggaagtgca gttattcatg atagataact gcgctgacga ttggaggatc 2281 gcaatgacat ggcaacgaat tagtcaaata gggttagaac tttttatatg cgctatacat 2341 ccaattcctg gcgaatacta tttccagtgg acgacgaaat tggccaataa gaataaaaca 2401 attggcaccg aaatggtgcc atatgacgta gctttatcat tacctatgtt ccttcgatta 2461 tatttaatct gccgcgtaat gctgctgcat tcaaagctat tcacagatgc atcatcacgg 2521 agcattggcg ctctcaatag gattaatttt aacacaagat tcgttttaaa aactctaatg 2581 acaatatgtc cgggaacggt tctattggtc ttcatggtct cgctgtggat catcgcatcg 2641 tggacgctgc gtcagtgcga aagatttcat gatgaagaac acgcgaatct tttgaatgca 2701 atgtggctga tagcgataac atttttgagt gttggtttcg gtgatattgt tccgaatacg 2761 tactgtggac gtggtatcgc tgtcagtaca ggaataatgg gcgccggctg tacggctcta 2821 ctggtggccg tagtctctcg gaaactggag ctgacccgtg ctgagaagca tgtgcacaac 2881 ttcatgatgg acacgcagtt gacgaaacgg ctgaaaaatg ctgcggcgaa tgttctgcgt 2941 gaaacttggc tcatttacaa acatacaaga ctagtaaaac gggttaatcc cggccgtgta 3001 agaacccacc aaagaaagtt ccttctagct atatatgcgt tgcgaaaagt taaaatggat 3061 cagcgcaaac taatggataa tgcaaacaca ataactgaca tggctaagac acaaaacacg 3121 gtctacgaga taatatcgga catgtctagc cgtcaggatg ccatcgaaga gcgtttaacc 3181 aacctagagg acaaaatgca gagcatacaa gagcacatgg aaagccttcc agacctattg 3241 tctcgatgtc tgacccagca ccaggagcgg atcgagcagc ggcggaactt tttacatcct 3301 gacacagctg cagttgcccc cattcaagcg ccaacgcccc aatcgatgtt caatgcagcg 3361 cccatgctgt ttccacattc tagctgaata tcagaaagag agcgctccaa ctccgtgatt 3421 aacatcgaga tgctaacaat aaggccggat cgattctggc caacctcatt cgcaccccaa 3481 aaaccaacat caacatttac atcaacatca atgtctacgt caaagtgtaa acccgaattc 3541 gaagtggccg agacagcgct gaggcaacgc gtgctatcgc cgtcgttatc ggagtttcaa 3601 tcgaaatcgc aatcgagacc atcgtcacaa acgcaagagc acattttgca aagggagatc 3661 ataccgatgg taccgatcat accgatcata ccagtgatac cggaggacgc cgaatcgttg 3721 ggaaacacca atacgaacag caacagttcg cccgatcagc agaatgtgcc catgactata 3781 agtacagtac cgccatcgag ttcagcgccc gcattcacag cgaccggaag cggaggttcg 3841 gtgaccggaa ctagcggtgg cattgtgaaa tcgataacga tgaacgaacc gattacgacg 3901 gggagcggca agccgattgc ctcgaataag tttactagga aaagagaacg tgtatgcaat 3961 aatagtagtt aatagtagta gtcatagtta tagtaataat agaggtaaaa gtaatattag 4021 taattctaca agtcgaattt cgaactcggc cttttgtaaa taagcctctt cgagatgaga 4081 aaaaagtcaa atgttagcat atacatatta atatacagaa tacacacact atgtatccta 4141 tatctgtata cggatatata taggcctccc cacaaaacat ccaaaaagaa agcaaaaaaa 4201 caataagcga aaaccgaaca gaatatatgt atacatatat atgtcattgt gtaacttttt 4261 ttttttgtct aagttttagg ctaaacgtat ttgtaatatt tcaccttggg ccaaggcagc 4321 ctgtacatgc atactaaaat acttaacata atatagcatg taggggggag tgtatgtgtg 4381 tgtatgtgca tgggagtgtg cgaatgcgag tgtacaggac cagattggta aggaagttag 4441 gtcatatgta ggacatagat cgtagggcac cagcatgtag aatccacgta tataaacgct 4501 cagaaatagc aacagaaata gcaatagcaa accttaaaga tctggcacca aaagtccata 4561 acagtaaatt cgtatatccc ttaaagaact gcaaccccca gcacttccgc ttccggtgca 4621 gcgccaacca actgcaaaac atccacgaac atggcaaatt ctcgtgtccg tctgtctcga 4681 atttgtgtgc atatataaat tgtatccgaa ggatgtgtgt ctgacctgac tgtgtgtgcg 4741 aggcaagtga aagcataagc atacgaggaa cccattaaag cccccaacaa ttatacacaa 4801 aacgacgcat aacaacaaaa aaaaaaaaag aactacaaga actaaatccc aaaagaagaa 4861 caatgaaaaa ctatactaac tgtaaagtgc atgttgcgag atttagaaaa cagcaaaacc 4921 agaaaaccaa aaactaagag ataatgaaac aaatgaaacc ccaataaccg agaataaacg 4981 aaaaataaac acacaagatg taagttctta cttaatatct acataccata ctatgtagat 5041 ctggctttaa ctaaactaac gaaaccaatt taaaggaaac aagtttgttg ttgtcttctt 5101 tttctacaca tatattaaaa tatatatagt atatatacat acatatatat attttcgttg 5161 ttgctgtttt tcgcccattc ttttctacca agaattatga actcaattaa gaacctgaat 5221 agcttttgaa tgaagttaaa gacgaagatt acagtagcgt agactaaact gagtaaacaa 5281 atgagaagaa aagaagtcgc aaaacgaact atttagtata gtctacatac taaagtgaac 5341 aattttaatt ggaatttttt gtaacatatt aaagtaaatc ccattaatat acaagctagc 5401 tggcaaatgt gtaacaacaa cggaacaaac aacaagctcc agatagaaaa taatattacc 5461 gaaccgaagt gtacggaagc gagttgatag agcagtgtat agtgtagaca taatagcaga 5521 agtggccgag ctacgtaaag attttctaaa gattctaaaa ggaacattat atatactata 5581 tatatatata tacatatact tactataaag tattaactga gagcatcgaa gttatttaaa 5641 gtaaaaatca aagcaagaaa acaaacaatt aggtaatgtg caaccttcta acgctttgtt 5701 aggttcccaa gtttccaaat tgaagacaaa tgagatatac aactgaattc cccgaatagt 5761 gccccccacc atccagctcc ccaaaattcc acccatcatc gcacaaactc cccatttccc 5821 ccgtcagtga gacagactct gcatattata ctgaaccagg gccagaaagg atcaaaatat 5881 ctgtaaactg tagattatat agccatagga tgcagtccac tttaagccaa ctaagagtat 5941 cggagtttta acacaatgat ttaccacatc tccaagcccc tggcctaagt tttgatttat 6001 gaaaacgaaa ctacccgcta ccaaaaaaag tttcccaact gtctgatagg tcttaactta 6061 tatgtatttg tacaactaaa ggcccagaca agaaatgaaa tgaaaaagga gaacaaggaa 6121 caagtaacaa accaactaaa tgaaccctta aacaaatgtg tgtataccta tttataatat 6181 tgaatattta aattgaaatg aacgttcaag actgctgtca aaatagcttt atcacaataa 6241 ttaacaaaga tctacacaag acgataacac accagacaca acagaacaga acaaaacaga 6301 acagaaccga tcagaacaat actaaggata tcataatcga ttatcgaatc gaaacagttt 6361 atcgaaccgg aaacacacag caacacacag attcagatac gcggtatgga atgcggccag 6421 ctttaacgtt atgtattcat gcatatttgg gtttcaattc tacaacaact taaaacgaat 6481 acgcagaata acaccgttat tgatcgatat acaattaacg atatatggag tcgaatcaaa 6541 tcgaatcgaa tcgaatcgaa ttgaatcgaa ttgaattgaa ttgagtaatt ggtgcaagat 6601 caaattcccg tttgaactgg tttcctaagc ccaaccaaat accttttaac acgagataaa 6661 aaccaaaaac tttgatatga gggaccgaat ttccaaagac aggtctttat tatacaaaat 6721 accgaagcag aagcaaacca actaacaatg aattcctaag taacaacatt taacagtaac 6781 aatttataat acgcaagatt ttaagccgcc ttagagctgg gttccaaaaa aaaaaaaaac 6841 aaaaaaaaaa ctaaggcaca cattgaagga tcgtattgca ccatgtcctt ggttgacttt 6901 cgtagcattt taggttcgag ttccatgtcc agctttgtgt tacattgtcc atttgtgttt 6961 ttttttttaa actagactca catcgaatcg aattgaatcg ataaatgttg tatactttct 7021 tttcctcagc gaatcgtaga gctcaagggg tacttcgaga atcatgcttc aacaaccgta 7081 actcttctag ccaaaccagg tccaatagaa catacatatg tatgtacata cgtgtgtatg 7141 tatagcccag tcaatgccaa tgctaatgaa gaactggatt cgtgttttcg aaaacgtttc 7201 gaaccggatt gtgacgaagc agccattttg gtgtatttac acgatagaat ctagaaatgg 7261 gtccttctcc caaaaatatc ccccacaccc caaatccctc ctctcgtgcg cccaactaga 7321 tcggggtatg caaaatatat atggttacat atacaatatc tagatataca acacacatac 7381 atatactcgt atatacatgt acagacggtc aatgaggtgt atacccaaca gcccaaaagc 7441 cagaaacaaa aaaaaaaacc caaaagaaaa taataaaaaa aaaaacaaaa caaaaaaaaa 7501 cacactaata agatcatatt tgactttata tgtattatag taatgtattc agtagctaaa 7561 tcgaaagccg aagcaaagac caatttatta acaacaaact aataaggaaa acccaactgg 7621 aaaacaatta ttatgttaaa ctaaacaata aaaacataag aggaaggcga aacaattttt 7681 tatggagaaa aaaagatgtg aaaacaaaag agaagtaatg aaagtaaact agaatgcgtt 7741 gcatgaatta aacgaagtgg agaaaaacta atagaaagca aaacttgaat aaagctaaac 7801 aaatgtcaac taaaaccaaa ctttaactaa acctacacta atgctaaaac taaaactaaa 7861 ataacattaa attaaaccaa ctaaaagaag gacgatttaa tttctaaaag aaataaagta 7921 agaaactaaa ctgaaaaaaa aaaaacaaca gcaaaaattc agtgactaat gaaatagttt 7981 attttgaatt tactgtattg tatatttaaa tttaacaagg gaaacaaccc ccccaaacaa 8041 agtatattgt tatatcttat cgaggaaccg tgttttgcaa aagctttaat ataatattta 8101 gggtgcctac atttgctaaa ttagtatttt acgatttaaa aaccaaggaa caaaccaaaa 8161 aaaatataag aaaaaaaatg aagagaaaat aaatacaaat actaaaacca acacctacat 8221 acacgaaata gtgaaaagct tgattaaaac gaacccaaaa agttaggagc ctcgatttcc 8281 aaaacgaaat acactgaata tagagaaacc gaaatcgata ccaaaacaaa ttaagaacag 8341 ctaaagcaaa tattgtattt gtatttgaga tatgaatttt aagaatgttt attagactta 8401 cgatttgtta ttttgtatac atatatatat atatatatat atatatatat atatattata 8461 tgtattatgt atgtagtata aactgatctg atctgaagac gattgtaatt gttttttttt 8521 tttgctcatt aagcatttac ctcataagaa ttcccactat ttatagcaaa tttaccatat 8581 tacataaatc aattgctgta ctgttataat gtacgatccc caagaaagcg aaaagcaaca 8641 agaagagcca ttaaatgaaa gagatcaatg gaagtcgagg ggagatagga aaactcataa 8701 aattgtaaat tattaattaa taaagaaacc aaagagaata attgaaattt taacaataat 8761 aaagggcttt gtatgaaaga aaaacaaaca aaaactgaat aaaaatgaaa taaaaataaa 8821 agaaaatc //